Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Grace Q Zhao"'
Autor:
Jing Ren, Alina Isakova, Drew Friedmann, Jiawei Zeng, Sophie M Grutzner, Albert Pun, Grace Q Zhao, Sai Saroja Kolluru, Ruiyu Wang, Rui Lin, Pengcheng Li, Anan Li, Jennifer L Raymond, Qingming Luo, Minmin Luo, Stephen R Quake, Liqun Luo
Publikováno v:
eLife, Vol 8 (2019)
Serotonin neurons of the dorsal and median raphe nuclei (DR, MR) collectively innervate the entire forebrain and midbrain, modulating diverse physiology and behavior. To gain a fundamental understanding of their molecular heterogeneity, we used plate
Externí odkaz:
https://doaj.org/article/eb730726e1314fd5a7371c54603afbe4
Autor:
TD Barbara Nguyen-Vu, Grace Q Zhao, Subhaneil Lahiri, Rhea R Kimpo, Hanmi Lee, Surya Ganguli, Carla J Shatz, Jennifer L Raymond
Publikováno v:
eLife, Vol 6 (2017)
Across many studies, animals with enhanced synaptic plasticity exhibit either enhanced or impaired learning, raising a conceptual puzzle: how enhanced plasticity can yield opposite learning outcomes? Here, we show that the recent history of experienc
Externí odkaz:
https://doaj.org/article/0e2fd4986302466e8fec0a76349b0c39
Publikováno v:
Cancer Research. 83:259-259
To accommodate the growing demands of sample throughput, reliability, and reduced hands-on time of targeted sequencing, automation is critical. The implementation of sample preparation automation is limited by several factors — complicated protocol
Publikováno v:
Journal of Clinical Oncology. 40:10542-10542
10542 Background: Cancer patient survival can be greatly improved by early detection. Cell-free DNA (cfDNA)-based cancer detection using targeted methylation sequencing (TMS) holds great promise. Here, we report the performance of the first cfDNA TMS
Autor:
Jianmin Wang, Shengrong Lin, Yingmin Wang, Heng Wang, Wanping Wang, Vanita Natu, Jayashree P. Joshi, Yun Bao, Grace Q. Zhao, Elena Arzumanyan, John A. Coller
Publikováno v:
Cancer Research. 81:LB059-LB059
Genomic and epigenetic changes are known to be the underlying mechanism of cancer development. Assessing the genomic (mutation) and epigenetic (methylation) changes has become increasingly important for cancer detection and treatment selection, espec
Autor:
Hongchao Xiong, Ke-Neng Chen, Xiaozheng Kang, Dequan Tian, Shengrong Lin, Guobing Xu, Grace Q. Zhao, Zhen Liang, Ting Xu, Yongbo Yang, Xiaofang You, Wanpu Yan, Liang Dai
Publikováno v:
Theranostics
Analysis of circulating tumor DNA (ctDNA) is emerging as a powerful tool for guiding targeted therapy and monitoring tumor evolution in patients with non-small cell lung cancer (NSCLC), especially when representative tissue biopsies are not available
Publikováno v:
Journal of Clinical Oncology. 39:3043-3043
3043 Background: Assessing the genomic and epigenomic changes on plasma cell-free DNA (cfDNA) using next-generation sequencing (NGS) has become increasingly important for cancer detection and treatment selection guidance. However, two major hurdles o
Publikováno v:
Cancer Research. 80:LB-290
Methylation analysis in cell-free DNA holds great potential for early cancer detection. In the plasma of early stage cancer patient, the tumor content is estimated to be less than 0.1%, often down to 0.01% or lower, therefore demands a highly sensiti
Publikováno v:
Journal of Clinical Oncology. 38:4092-4092
4092 Background: Methylation analysis in cell-free DNA holds great potential for early cancer detection. In the plasma of early stage cancer patient, the tumor content is estimated to be less than 0.1%, therefore demands a highly sensitive assay. Tar
Autor:
Malek Fahem, Min Li, Lin Wang, Shengrong Lin, Hongyan Wang, Grace Q. Zhao, Qiaomei Guo, Xiao Chen, Li Weng, Jiatao Lou, Wenjun Yu, Tobias Wittkop
Publikováno v:
Cancer Research. 78:938-938
Background: Detection of EGFR, KRAS and BRAF mutations can help guide cancer treatment for non-small cell lung cancer (NSCLC) patients. To identify an easy to use, accurate, multiplex molecular diagnostic assay, we evaluated the performance of a nove