Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Grace Muzanyi"'
Autor:
Mary A De Groote, Payam Nahid, Leah Jarlsberg, John L Johnson, Marc Weiner, Grace Muzanyi, Nebojsa Janjic, David G Sterling, Urs A Ochsner
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61002 (2013)
In an unbiased approach to biomarker discovery, we applied a highly multiplexed proteomic technology (SOMAscan, SomaLogic, Inc, Boulder, CO) to understand changes in proteins from paired serum samples at enrollment and after 8 weeks of TB treatment f
Externí odkaz:
https://doaj.org/article/8bef189a5f16488fada6ae29bf0d781b
Publikováno v:
African Health Sciences
Background: Tuberculosis (TB) sputum culture contaminants make it difficult to obtain pure TB isolates.We aimed to study and identify persistent TB sputum culture contaminants post the standard laboratory pre-culture sample decontamination techniques
Publikováno v:
African Health Sciences; Vol. 22 No. 2 (2022): Special Issue: Makerere@100; 51-6.
Background: Collaborative research between institutions may not yield results to transform communities. Many research collaborations come to the end of their life time without achieving their originally set goals and with a dearth of community transf
Autor:
April C, Pettit, Patrick Pj, Phillips, Ekaterina, Kurbatova, Andrew, Vernon, Payam, Nahid, Rodney, Dawson, Kelly E, Dooley, Ian, Sanne, Ziyaad, Waja, Lerato, Mohapi, Anthony T, Podany, Wadzanai, Samaneka, Rada M, Savic, John L, Johnson, Grace, Muzanyi, Umesh G, Lalloo, Kia, Bryant, Erin, Sizemore, Nigel, Scott, Susan E, Dorman, Richard E, Chaisson, Susan, Swindells
Publikováno v:
Clin Infect Dis
BACKGROUND: Tuberculosis (TB) Trials Consortium Study 31/AIDS Clinical Trials Group A5349, an international randomized open-label phase 3 noninferiority trial showed that a 4-month daily regimen substituting rifapentine for rifampin and moxifloxacin
Autor:
David Kaawa Mafigiri, Joanita Nassali, Grace Muzanyi, Gladys Nalugwa, Isaac Sekitoleko, John L. Johnson, Jane Lunkuse
Publikováno v:
African Health Sciences
Background: Low education levels and language barriers present challenges in obtaining informed consent for clinical research. Objective: To describe and correlate the association between the level of education and the participant’s preferred langu
Autor:
Anne E. Purfield, Nigel A. Scott, Samuel Pierre, Madeleine Lourens, Richard E. Chaisson, Melissa Engle, Payam Nahid, Erin Sizemore, Patrick P. J. Phillips, Ziyaad Waja, Kelly E. Dooley, Susan Swindells, Marc H Weiner, Ekaterina V. Kurbatova, Kim Narunsky, Radojka M. Savic, Susan E. Dorman, Sandy Nerette, Nhung Viet Nguyen, Wadzanai Samaneka, Ha T.T. Phan, James Hakim, Andrew Vernon, Thuong H. Pham, Grace Muzanyi, Stefan V. Goldberg, Justin Shenje, John L. Johnson, Neil A. Martinson, Kia E Bryant, Ian Sanne
Publikováno v:
The New England journal of medicine, vol 384, iss 18
BackgroundRifapentine-based regimens have potent antimycobacterial activity that may allow for a shorter course in patients with drug-susceptible pulmonary tuberculosis.MethodsIn an open-label, phase 3, randomized, controlled trial involving persons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3229ece147fe062e786e2a34a8ab15fd
https://escholarship.org/uc/item/30c34231
https://escholarship.org/uc/item/30c34231
Autor:
Moses Joloba, I. Sekitoleko, Charles M Bark, John L. Johnson, Sam Ogwang, Bonnie Thiel, Grace Muzanyi
Publikováno v:
The International Journal of Tuberculosis and Lung Disease. 22:306-308
The sputum smear-positive, culture-negative state poses a challenge for clinicians. Previous studies have shown that most samples with positive smears during the later stages of treatment are culture-negative. Earlier studies generally used solid cul
Autor:
William R. MacKenzie, Emily J. Hecker, Ruth N. Moro, Pei Jean I Feng, Radojka M. Savic, John L. Johnson, Marc H Weiner, Susan E. Dorman, Grace Muzanyi, Eric L. Nuermberger, Charles M. Heilig, Andrew Vernon, Stefan V. Goldberg, Kelly E. Dooley, Neil W. Schluger, Payam Nahid, Lorna Bozeman, Jason E. Stout
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 191:333-343
Rifapentine has potent activity in mouse models of tuberculosis chemotherapy but its optimal dose and exposure in humans are unknown.We conducted a randomized, partially blinded dose-ranging study to determine tolerability, safety, and antimicrobial
Publikováno v:
African Health Sciences
African Health Sciences; Vol 19, No 2 (2019); 2091-2099
African Health Sciences; Vol 19, No 2 (2019); 2091-2099
Objective: To explore simple inexpensive non-culture based predictors of recurrent pulmonary tuberculosis (PTB). Setting and study population: HIV-infected and uninfected adults with the first episode of smear positive, culture-confirmed pulmonary tu
Autor:
Stefan V. Goldberg, John L. Johnson, M. Elsa Villarino, Richard E. Chaisson, Grace Muzanyi, Fred M. Gordin, William J. Burman, Andrew Vernon, Jussi J. Saukkonen, Craig M. Hales, Chi Chiu Leung, Charles M. Heilig, Kwok Chiu Chang
Publikováno v:
Annals of the American Thoracic Society. 10:18-25
The lack of consistent associations between clinical outcomes and microbiological responses to therapy for some infectious diseases has raised questions about the adequacy of microbiological endpoints for tuberculosis treatment trials.To evaluate the