Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Grace M. Wynn"'
Autor:
Alev Cagla Ozdemir, Grace M Wynn, Aimee Vester, M Neale Weitzmann, Gretchen N Neigh, Shanthi Srinivasan, M Katharine Rudd
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188763 (2017)
The G-protein beta subunit 3 (GNB3) gene has been implicated in obesity risk; however, the molecular mechanism of GNB3-related disease is unknown. GNB3 duplication is responsible for a syndromic form of childhood obesity, and an activating DNA sequen
Externí odkaz:
https://doaj.org/article/6377138046d049ce892d693e55016244
Autor:
Joshua A. Owens, Eric A. Ortlund, Grace M. Wynn, Jason D. Matthews, Brian S. Robinson, Kristal M. Maner-Smith, Rheinallt M. Jones, Liping Luo, Trevor Darby, Crystal Naudin, Alexandra A. Wolfarth, April R. Reedy
Publikováno v:
Gastroenterology. 159:639-651.e5
Background & Aims A Western-style diet, which is high in fat and sugar, can cause significant dyslipidemia and nonalcoholic fatty liver disease; the diet has an especially strong effect in women, regardless of total calorie intake. Dietary supplement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531611153b4e46442ed416a2dcc20762
https://doi.org/10.1053/j.gastro.2020.03.010
https://doi.org/10.1053/j.gastro.2020.03.010
Publikováno v:
Cell Host & Microbe. 15:351-362
Summary Peripheral blood myelomonocytic cells are important for cytomegalovirus dissemination to distal organs such as salivary glands where persistent replication and shedding dictates transmission patterns. We find that this process is markedly enh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046450e7501e25bfed001d78ae8c349a
https://doi.org/10.1016/j.chom.2014.02.002
https://doi.org/10.1016/j.chom.2014.02.002
Autor:
Shanthi Srinivasan, M. Neale Weitzmann, Alev Cagla Ozdemir, Grace M. Wynn, M. Katharine Rudd, Gretchen N. Neigh, Aimee Vester
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188763 (2017)
PLoS ONE
PLoS ONE
The G-protein beta subunit 3 (GNB3) gene has been implicated in obesity risk; however, the molecular mechanism of GNB3-related disease is unknown. GNB3 duplication is responsible for a syndromic form of childhood obesity, and an activating DNA sequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd72968a6bf4e86c40e1a348ea2d6de
http://europepmc.org/articles/PMC5716578?pdf=render
http://europepmc.org/articles/PMC5716578?pdf=render
Publikováno v:
Virology. 435:250-257
At a low MOI (≤0.01), cytomegalovirus-associated programmed cell death terminates productive infection via a pathway triggered by the mitochondrial serine protease HtrA2/Omi. This infected cell death is associated with late phase replication events
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b4c07256e8b594cdcc0a31488933f8e
https://doi.org/10.1016/j.virol.2012.08.042
https://doi.org/10.1016/j.virol.2012.08.042
Autor:
Jamie E. Mells, Wujuan Zhang, Brad T. Keller, Hao Wu, Saul J. Karpen, Grace M. Wynn, Kenneth D.R. Setchell, Astrid Kosters, Dean P. Jones, Paul A. Dawson, Tianlei Xu, Sophia Banton, Hong Yin, Angélica M. Amanso, Anuradha Rao
Publikováno v:
Science Translational Medicine. 8
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the Western world, and safe and effective therapies are needed. Bile acids (BAs) and their receptors [including the nuclear receptor for BAs, farnesoid X receptor (F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b5f1a0cae883826a12653fc6059166
https://doi.org/10.1126/scitranslmed.aaf4823
https://doi.org/10.1126/scitranslmed.aaf4823
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f345108fabc9d98e5bd77dec2ea75195
https://doi.org/10.1530/endoabs.41.oc12.5
https://doi.org/10.1530/endoabs.41.oc12.5
Autor:
Ian S. Goldlust, Jay W. Ellison, Rebecca Cozad, Madhuri Hegde, Jill A. Rosenfeld, Karen N. Conneely, Karen Hermetz, M. Katharine Rudd, Alev Cagla Ozdemir, Lisa M. Catalano, Laurie A. Demmer, Erik C. Thorland, Brad Angle, Jennifer G. Mulle, Blake C. Ballif, Richard Barfield, Alison Colley, Lisa G. Shaffer, Grace M. Wynn, Katherine H. Kim, Amy E Webb, Shikha Dharamrup
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 110(37)
Obesity is a highly heritable condition and a risk factor for other diseases, including type 2 diabetes, cardiovascular disease, hypertension, and cancer. Recently, genomic copy number variation (CNV) has been implicated in cases of early onset obesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e41465eb20c02d052c882cca0622749
https://pubmed.ncbi.nlm.nih.gov/23980137
https://pubmed.ncbi.nlm.nih.gov/23980137
Publikováno v:
Immunity. 37(1)
Summary Inflammatory monocytes are key early responders to infection that contribute to pathogen-host interactions in diverse ways. Here, we report that the murine cytomegalovirus-encoded CC chemokine, MCK2, enhanced CCR2-dependent recruitment of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dfe9cea3b123fe80c41cf9a8c1fe01a
https://pubmed.ncbi.nlm.nih.gov/22840843
https://pubmed.ncbi.nlm.nih.gov/22840843