Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Grace M, Uptergrove"'
Autor:
Nicholas Szary, R. Scott Rector, Grace M. Uptergrove, Suzanne E. Ridenhour, Shivendra D. Shukla, John P. Thyfault, Lauren G. Koch, Steven L. Britton, Jamal A. Ibdah
Publikováno v:
Biomolecules, Vol 5, Iss 4, Pp 3295-3308 (2015)
Rats artificially selected over several generations for high intrinsic endurance/aerobic capacity resulting in high capacity runners (HCR) has been developed to study the links between high aerobic fitness and protection from metabolic diseases (Wisl
Externí odkaz:
https://doaj.org/article/a8794658ed1f46e2be282f0fb859ac9f
Autor:
Sarah J. Borengasser, R. Scott Rector, Grace M. Uptergrove, E. Matthew Morris, James W. Perfield, Frank W. Booth, Kevin L. Fritsche, Jamal A. Ibdah, John P. Thyfault
Publikováno v:
Journal of Nutrition and Metabolism, Vol 2012 (2012)
Background and Aims. This study examined if exercise and omega-3 fatty acid (n3PUFA) supplementation is an effective treatment for hepatic steatosis in obese, hyperphagic Otsuka Long-Evans Tokushima Fatty (OLETF) rats. Methods. Male OLETF rats were d
Externí odkaz:
https://doaj.org/article/f2385f7d1d2f4563b700f9c8e97644fc
Autor:
Catherine R. Mikus, M. H. Laughlin, John P. Thyfault, Sarah J. Borengasser, Grace M. Uptergrove, Angelina M. Taylor, Jessica L. Libla, R. Rector, Jamal A. Ibdah, E. Matthew Morris, Douglas J. Oberlin, Bruno T. Roseguini
Publikováno v:
Microcirculation. 19:729-738
Background Exercise (RUN) prevents declines in insulin-mediated vasodilation, an important component of insulin-mediated glucose disposal, in rats prone to obesity and insulin resistance. Objective Determine whether RUN (1) improves insulin-stimulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd37f8d20161f1b9cd378c10e87ea45d
https://doi.org/10.1111/j.1549-8719.2012.00210.x
https://doi.org/10.1111/j.1549-8719.2012.00210.x
Autor:
John P. Thyfault, E. Matthew Morris, Frank W. Booth, Grace M. Uptergrove, M. Harold Laughlin, Catherine R. Mikus, Matthew J. Laye, Scott P. Naples, R. Scott Rector, Sarah J. Borengasser, Jamal A. Ibdah
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 298:E1179-E1187
The temporal changes in skeletal muscle mitochondrial content and lipid metabolism that precede type 2 diabetes are largely unknown. Here we examined skeletal muscle mitochondrial fatty acid oxidation (MitoFAOX) and markers of mitochondrial gene expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::590199a77b2d7dd22bc0bfe53a1f8395
https://doi.org/10.1152/ajpendo.00703.2009
https://doi.org/10.1152/ajpendo.00703.2009
Autor:
John P. Thyfault, Masahiro Horiuchi, Paul J. Fadel, Catherine R. Mikus, Areum Kim, Grace M. Uptergrove, Shekhar H. Deo, Colin N. Young
Publikováno v:
Journal of Applied Physiology. 108:882-890
Nutrient intake is accompanied by increases in central sympathetic outflow, a response that has been mainly attributed to insulin. Insulin-mediated sympathoexcitation appears to be blunted in insulin-resistant conditions, suggesting that aside from p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::037cd28e3d42ff7dcca5b1117ab31b27
https://doi.org/10.1152/japplphysiol.01174.2009
https://doi.org/10.1152/japplphysiol.01174.2009
Autor:
Aspen L. Perretta, Grace M. Uptergrove, Jamal A. Ibdah, Shana O. Warner, R. Scott Rector, John P. Thyfault, Frank W. Booth, Scott P. Naples, Matthew J. Laye, M. Harold Laughlin
Publikováno v:
The Journal of Physiology. 587:3729-3739
Using the hyperphagic, obese, Otsuka Long–Evans Tokushima Fatty (OLETF) rat, we sought to determine if progression to type 2 diabetes alters visceral white adipose tissue (WAT) mitochondrial content and if these changes are modified through prevent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c4d4815e2bcfb46ed263d077a8b50e1
https://doi.org/10.1113/jphysiol.2009.172601
https://doi.org/10.1113/jphysiol.2009.172601
Autor:
Suzanne E. Ridenhour, Sarah J. Borengasser, S. L. Britton, Yongzhong Wei, Lauren G. Koch, E. Matthew Morris, Jamal A. Ibdah, Grace M. Uptergrove, John P. Thyfault, R. Scott Rector, Charles F. Burant, Matthew J. Laye, Nathan Qi
Publikováno v:
The Journal of Physiology. 587:1805-1816
Fatty liver has been linked to low aerobic fitness, but the mechanisms are unknown. We previously reported a novel model in which rats were artificially selected to be high capacity runners (HCR) and low capacity runners (LCR) that in a sedentary con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89b4b3076b8527d2d918524f005feb49
https://doi.org/10.1113/jphysiol.2009.169060
https://doi.org/10.1113/jphysiol.2009.169060
Autor:
R. Scott Rector, John P. Thyfault, Grace M. Uptergrove, Frank W. Booth, R. Tyler Morris, Matthew J. Laye, Jamal A. Ibdah, Manu V. Chakravarthy, Sarah J. Borengasser
Publikováno v:
The Journal of Physiology. 586:4241-4249
The purpose of this study was to delineate potential mechanisms initiating the onset of hepatic steatosis following the cessation of daily physical activity. Four-week-old, hyperphagic/obese Otsuka Long-Evans Tokushima Fatty rats were given access to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7118fce6bf340662b141d068bd1bc0d0
https://doi.org/10.1113/jphysiol.2008.156745
https://doi.org/10.1113/jphysiol.2008.156745
Autor:
Yongzhong Wei, Carlos M. Ferrario, John P. Thyfault, Suzanne E. Clark, Adam Whaley-Connell, E. Matthew Morris, Jamal A. Ibdah, Grace M. Uptergrove, James R. Sowers
Publikováno v:
Journal of Hepatology. 49:417-428
Background/Aims Non-alcoholic fatty liver disease (NAFLD) is a common health problem and includes a spectrum of hepatic steatosis, steatohepatitis and fibrosis. The renin–angiotensin system (RAS) plays a vital role in blood pressure regulation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a006d47fab21281dfe32b618d27401b
https://doi.org/10.1016/j.jhep.2008.03.018
https://doi.org/10.1016/j.jhep.2008.03.018
Autor:
Grace M. Uptergrove, James R. Sowers, Suzanne E. Clark, Carlos M. Ferrario, Yongzhong Wei, Kemin Chen, Javad Habibi, Craig S. Stump, Adam Whaley-Connell
Publikováno v:
Hypertension. 50:384-391
Reduced insulin sensitivity is characteristic of various pathological conditions such as type 2 diabetes mellitus and hypertension. Angiotensin II, acting through its angiotensin type 1 receptor, inhibits the actions of insulin in the vasculature whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23be8a69ecf9049367eeae002e10716e
https://doi.org/10.1161/hypertensionaha.107.089284
https://doi.org/10.1161/hypertensionaha.107.089284