Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Grace L. Chen"'
Autor:
Yuhe R. Yang, Julianna Han, Hailee R. Perrett, Sara T. Richey, Alesandra J. Rodriguez, Abigail M. Jackson, Rebecca A. Gillespie, Sarah O’Connell, Julie E. Raab, Lauren Y. Cominsky, Ankita Chopde, Masaru Kanekiyo, Katherine V. Houser, Grace L. Chen, Adrian B. McDermott, Sarah F. Andrews, Andrew B. Ward
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114171- (2024)
Summary: Influenza A virus subtype H2N2, which caused the 1957 influenza pandemic, remains a global threat. A recent phase 1 clinical trial investigating a ferritin nanoparticle vaccine displaying H2 hemagglutinin (HA) in H2-naive and H2-exposed adul
Externí odkaz:
https://doaj.org/article/a0c95ce71b2948fb906573474156e723
Autor:
Grace L. Chen, Jay G. Silverman, Anvita Dixit, Shahina Begum, Mohan Ghule, Madhusudana Battala, Nicole E. Johns, Anita Raj, Sarah Averbach
Publikováno v:
EClinicalMedicine, Vol 21, Iss , Pp - (2020)
Background: Intimate partner violence (IPV) has been shown to be associated differentially with contraceptive use based on type, with IPV more likely among pill users and less likely among condom users. Recent increases in IUD uptake allow considerat
Externí odkaz:
https://doaj.org/article/a583114fd54348df810a345c835bc212
Publikováno v:
School Psychology International. 44:154-171
Given the individual and systemic stress endured by children and families during the COVID-19 pandemic, research examining culturally responsive school experiences and supports to enhance resilience is critical. This study examined the relationship b
Autor:
Grace L Chen, Runa Mithani, Archana Kapoor, Sophia Lu, Laila El Asmar, Catherine A Panozzo, Christine A Shaw, Sonia K Stoszek, Allison August
Publikováno v:
Open Forum Infectious Diseases. 9
Background Respiratory syncytial virus (RSV) is a public health burden; no vaccine is currently available. An mRNA-based RSV vaccine (mRNA-1345) encoding the RSV prefusion stabilized F (preF) glycoprotein is under clinical investigation. Methods A ph
Autor:
Cristina Carter, Katherine V Houser, Galina V Yamshchikov, Abbie R Bellamy, Jeanine May, Mary E Enama, Uzma Sarwar, Brenda Larkin, Robert T Bailer, Richard Koup, Grace L Chen, Shital M Patel, Patricia Winokur, Robert Belshe, Cornelia L Dekker, Barney S Graham, Julie E Ledgerwood, VRC 703 study team
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222178 (2019)
BackgroundSeasonal influenza results in significant morbidity and mortality worldwide, but the currently licensed inactivated vaccines generally have low vaccine efficacies and could be improved. In this phase 1 clinical trial, we compared seasonal i
Externí odkaz:
https://doaj.org/article/773f84c8b2754fefbbb0e4d8279bce2c
Autor:
Sarah F. Andrews, Lauren Y. Cominsky, Geoffrey D. Shimberg, Rebecca A. Gillespie, Jason Gorman, Julie E. Raab, Joshua Brand, Adrian Creanga, Suprabhath R. Gajjala, Sandeep Narpala, Crystal S. F. Cheung, Darcy R. Harris, Tongqing Zhou, Ingelise Gordon, LaSonji Holman, Floreliz Mendoza, Katherine V. Houser, Grace L. Chen, John R. Mascola, Barney S. Graham, Peter D. Kwong, Alicia Widge, Lesia K. Dropulic, Julie E. Ledgerwood, Masaru Kanekiyo, Adrian B. McDermott
Publikováno v:
Science Translational Medicine. 15
Current yearly seasonal influenza vaccines primarily induce an antibody response directed against the immunodominant but continually diversifying hemagglutinin (HA) head region. These antibody responses provide protection against the vaccinating stra
Autor:
Lauren A. Chang, Emily Phung, Michelle C. Crank, Kaitlyn M. Morabito, Tonya Villafana, Filip Dubovsky, Judith Falloon, Mark T. Esser, Bob C. Lin, Grace L. Chen, Barney S. Graham, Tracy J. Ruckwardt
Publikováno v:
Science translational medicine. 14(676)
There is currently no licensed vaccine for respiratory syncytial virus (RSV). Here, we assess the effect of RSV fusion protein (F) conformation on B cell responses in a post hoc comparison of samples from the DS-Cav1 [prefusion (pre-F)] and MEDI7510
Autor:
Martin R Gaudinski, Emily E Coates, Katherine V Houser, Grace L Chen, Galina Yamshchikov, Jamie G Saunders, LaSonji A Holman, Ingelise Gordon, Sarah Plummer, Cynthia S Hendel, Michelle Conan-Cibotti, Margarita Gomez Lorenzo, Sandra Sitar, Kevin Carlton, Carolyn Laurencot, Robert T Bailer, Sandeep Narpala, Adrian B McDermott, Aryan M Namboodiri, Janardan P Pandey, Richard M Schwartz, Zonghui Hu, Richard A Koup, Edmund Capparelli, Barney S Graham, John R Mascola, Julie E Ledgerwood, VRC 606 Study Team
Publikováno v:
PLoS Medicine, Vol 15, Iss 1, p e1002493 (2018)
BACKGROUND:VRC01 is a human broadly neutralizing monoclonal antibody (bnMAb) against the CD4-binding site of the HIV-1 envelope glycoprotein (Env) that is currently being evaluated in a Phase IIb adult HIV-1 prevention efficacy trial. VRC01LS is a mo
Externí odkaz:
https://doaj.org/article/7064e5c4178543e0a29e54c0e8e750e5
Autor:
Peifeng Chen, Anita Arthur, Kaitlyn M. Morabito, Kristin Leach, Xiaolin Wang, Grace L. Chen, Attila Nagy, Lauren A. Chang, Jon Cooper, Amy L. Chamberlain, Janel Holland-Linn, Olga Vasilenko, Alicia T. Widge, Shufeng Bai, Judith A Stein, LaSonji A. Holman, Cristina Carter, Iris Pittman, Deepika Gollapudi, Lisa A. Kueltzo, Colleen Fridley, Michelle C. Crank, Amritha Menon, William Whalen, Mridul Ghosh, Cynthia S. Hendel, Martha Nason, Amy Liu, Althaf Hussain, Laura Novik, Pernell Williams, Maria Burgos Florez, Robert T. Bailer, Thuy Nguyen, Brenda Larkin, Tracy J. Ruckwardt, Pamela Costner, Lam Le, Zhong Zhao, Elizabeth Carey, Vera Ivleva, Jennifer Walters, John R. Mascola, Jennifer Cunningham, Olga Trofymenko, Ya-chen Chang, Somia P. Hickman, Martin R. Gaudinski, Richard M. Schwartz, Slobodanka D. Manceva, Kevin Carlton, Barney S. Graham, Rahul Ragunathan, Jason G. D. Gall, Ana M. Ortega-Villa, Colin Tran, Sarah H. Plummer, Abidemi Ola, Ro Shauna S Rothwell, Ingelise J. Gordon, Mingzhong Chen, Jamie G. Saunders, Aba Mensima Eshun, Bob C. Lin, Azad Kumar, Nina M. Berkowitz, Xun Liu, Cora Trelles Cartagena, Emily Phung, Galina Yamshchikov, Joe Horwitz, Sarah O’Connell, Florence Kaltovich, Floreliz Mendoza, LaShawn Requilman, Man Chen, Preeti Apte, Christopher Lee, Renunda Hicks
Publikováno v:
Lancet Respir Med
Multiple active vaccination approaches have proven ineffective in reducing the substantial morbidity and mortality caused by respiratory syncytial virus (RSV) in infants and older adults (aged ≥65 years). A vaccine conferring a substantial and sust
Publikováno v:
ACS Applied Polymer Materials. 3:3496-3503