Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Grace Ji-eun Shin"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Recent studies capitalizing on the newly complete nanometer-resolution Drosophila larval connectome have made significant advances in identifying the structural basis of motor patterning. However, the molecular mechanisms utilized by neurons to wire
Externí odkaz:
https://doaj.org/article/12d8ca47585445e6a422543f4277e2bc
Publikováno v:
Frontiers in Pain Research, Vol 3 (2022)
Chemotherapy-induced peripheral neuropathy (CIPN) is a highly prevalent and complex condition arising from chemotherapy cancer treatments. Currently, there are no treatment or prevention options in the clinic. CIPN accompanies pain-related sensory fu
Externí odkaz:
https://doaj.org/article/21eca5b843044ca4979eb8ad9f4597b1
Autor:
Anita Burgos, Ken Honjo, Tomoko Ohyama, Cheng Sam Qian, Grace Ji-eun Shin, Daryl M Gohl, Marion Silies, W Daniel Tracey, Marta Zlatic, Albert Cardona, Wesley B Grueber
Publikováno v:
eLife, Vol 7 (2018)
Rapid and efficient escape behaviors in response to noxious sensory stimuli are essential for protection and survival. Yet, how noxious stimuli are transformed to coordinated escape behaviors remains poorly understood. In Drosophila larvae, noxious s
Externí odkaz:
https://doaj.org/article/7c7d91a80d1d4f9684a3d7e21c07ce0a
Autor:
Atul Kumar, Delfina Larrea, Maria Elena Pero, Paola Infante, Marilisa Conenna, Grace Ji-eun Shin, Wesley B Grueber, Lucia Di Marcotullio, Estela Area-Gomez, Francesca Bartolini
Publikováno v:
bioRxiv
Acetylated microtubules play key roles in the regulation of mitochondria dynamics. It has however remained unknown if the machinery controlling mitochondria dynamics functionally interacts with the alpha-tubulin acetylation cycle. Mitofusin-2 (MFN2),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3575025411a6eb709120a31086167385
https://doi.org/10.1101/2023.03.15.532838
https://doi.org/10.1101/2023.03.15.532838
Axon and dendrite placement and connectivity is guided by a wide range of secreted and surface molecules in the developing nervous system. Nevertheless, the extraordinary complexity of connections in the brain requires that this repertoire be further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8abad1b22aea24e4e52b78c4e7511ba
https://doi.org/10.1101/2023.03.01.530539
https://doi.org/10.1101/2023.03.01.530539
Autor:
Grace Ji-eun Shin, Wesley B. Grueber
Publikováno v:
Journal of Cell Biology. 222
Disruptions in membrane trafficking are associated with neurodevelopmental disorders, but underlying pathological mechanisms remain largely unknown. In this issue, O’Brien et al. (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202112108) show how G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b39ff4c968a844394dc1b28538d5fd
https://doi.org/10.1083/jcb.202211072
https://doi.org/10.1083/jcb.202211072
Autor:
Grace Ji-Eun, Shin
Publikováno v:
Experimental Neurology. 359:114258
Paclitaxel is a common chemotherapeutic agent widely used to treat solid cancer. However, it frequently causes peripheral sensory neuropathy, resulting in sensory abnormalities and pain in patients receiving treatment for cancer. As one of the most w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d97e2586c7bdb06a8e7d238696c6331
https://doi.org/10.1016/j.expneurol.2022.114258
https://doi.org/10.1016/j.expneurol.2022.114258
Autor:
Wesley B. Grueber, Grace Ji-eun Shin, Atul Kumar, Samantha E Galindo, Anita Burgos, Maria Elena Pero, Tanguy Lucas, Francesca Bartolini, Luke A. Hammond
Publikováno v:
Proc Natl Acad Sci U S A
Chemotherapy-induced peripheral neuropathy (CIPN) is a major side effect from cancer treatment with no known method for prevention or cure in clinics. CIPN often affects unmyelinated nociceptive sensory terminals. Despite the high prevalence, molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa955a4e5ab0248b23df36db83402d4
https://europepmc.org/articles/PMC8053987/
https://europepmc.org/articles/PMC8053987/
Autor:
Giulia Fumagalli, Thomas H. Brannagan, Matthew Shorey, Melissa M. Rolls, Xiaoyi Qu, Wesley B. Grueber, Laura Monza, Kurenai Tanji, Grace Ji-eun Shin, Guido Cavaletti, Paola Alberti, Maria Elena Pero, Cristina Meregalli, Atul Kumar, Francesca Bartolini
Publikováno v:
Proc Natl Acad Sci U S A
The pathogenesis of chemotherapy-induced peripheral neuropathy (CIPN) is poorly understood. Here, we report that the CIPN-causing drug bortezomib (Bort) promotes delta 2 tubulin (D2) accumulation while affecting microtubule stability and dynamics in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::979672c9afe523584e0766be4b772afb
http://hdl.handle.net/10281/299750
http://hdl.handle.net/10281/299750
Publikováno v:
Genetics. 208:717-728
How the brain makes trillions of synaptic connections using a genome of only 20,000 genes is a major question in modern neuroscience. Alternative splicing is one mechanism that can increase the number of proteins produced by each gene, but its role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4d0fca55f8823217e51b5d670710ec5
https://doi.org/10.1534/genetics.117.300432
https://doi.org/10.1534/genetics.117.300432