Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Grace J Yuen"'
Autor:
Xiaojiang Tan, Beth Burgwyn Fuchs, Yan Wang, Weiping Chen, Grace J Yuen, Rosalyn B Chen, Elamparithi Jayamani, Cleo Anastassopoulou, Read Pukkila-Worley, Jeffrey J Coleman, Eleftherios Mylonakis
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94468 (2014)
Candida albicans is a ubiquitous fungus, which can cause very serious and sometimes life-threatening infections in susceptible patients. We used Caenorhabditis elegans as a model host to screen a library of C. albicans mutants for decreased virulence
Externí odkaz:
https://doaj.org/article/df867dbe221d406dadb9e8d2ec8e24c0
Autor:
Brent Cezairliyan, Nawaporn Vinayavekhin, Daniel Grenfell-Lee, Grace J Yuen, Alan Saghatelian, Frederick M Ausubel
Publikováno v:
PLoS Pathogens, Vol 9, Iss 1, p e1003101 (2013)
Pathogenic microbes employ a variety of methods to overcome host defenses, including the production and dispersal of molecules that are toxic to their hosts. Pseudomonas aeruginosa, a Gram-negative bacterium, is a pathogen of a diverse variety of hos
Externí odkaz:
https://doaj.org/article/ac2f0cc6876e4cc29f441e7ee3bf5b1c
Autor:
Grace J. Yuen, Frederick M. Ausubel
Publikováno v:
Virulence, Vol 9, Iss 1, Pp 683-699 (2018)
The innate immune response of the nematode Caenorhabditis elegans has been extensively studied and a variety of Toll-independent immune response pathways have been identified. Surprisingly little, however, is known about how pathogens activate the C.
Externí odkaz:
https://doaj.org/article/b7aa0223f6c246db8676c0f4d2a7c045
Autor:
Shiv Pillai, Samuel J.H. Murphy, Vinay Mahajan, Hugues Allard-Chamard, Na Sun, Grace J. Yuen, Hamid Mattoo, Annaiah Cariappa, Vinayak Viswanadham, Maimuna Ahmad, Yesim Tuncay
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications
Nature Communications
The B1 and B2 lineages of B cells contribute to protection from pathogens in distinct ways. The role of the DNA CpG methylome in specifying these two B-cell fates is still unclear. Here we profile the CpG modifications and transcriptomes of peritonea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0eee239ff6bbfae29faa7deb0e91b9c
https://doaj.org/article/3f5d4b4a728a40e5ad631b0536b74c49
https://doaj.org/article/3f5d4b4a728a40e5ad631b0536b74c49
Autor:
Na Sun, Vinay Mahajan, Grace J. Yuen, Jishnu Das, Syed Ashiqur Rahman, Hamid Mattoo, Vinayak Viswanadham, Shiv Pillai
T follicular helper (Tfh) cells play a critical role in T-dependent humoral immune responses. While genetic programs controlling Tfh cell differentiation have been extensively studied using murine models, studies in humans have been hampered by the l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58de1ad871772077decb9a0548b17d4f
https://doi.org/10.1101/2021.05.19.444859
https://doi.org/10.1101/2021.05.19.444859
Autor:
Hugues Allard-Chamard, Na Sun, Samuel J.H. Murphy, Vinay Mahajan, Yesim Tuncay, Maimuna Ahmad, Shiv Pillai, Vinayak Viswanadham, Cariappa Annaiah, Hamid Mattoo, Grace J. Yuen
We show that DNA methylation is a layered process in B lymphocytes. An underlying foundational methylome is stably established during B lineage commitment and overlaid with a DNMT3A-maintained dynamic methylome which is sculpted in distinct ways in B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c69b5ef2679ec31e6f52a552542c4afb
Autor:
Sudha Kumari, Vinay Mahajan, James J. Moon, Andrew Huang, Vinayak Viswanadham, Ezana Demissie, Darrell J. Irvine, Shiv Pillai, Johnson Q. Tran, Grace J. Yuen, Faisal Alsufyani
Publikováno v:
J Immunol
PMC
PMC
Copyright © 2019 by The American Association of Immunologists, Inc. The control of cytoskeletal dynamics by dedicator of cytokinesis 2 (DOCK2), a hematopoietic cell-specific actin effector protein, has been implicated in TCR signaling and T cell mig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d946e31aca62bc6a776bab984e73d79a
https://europepmc.org/articles/PMC6920543/
https://europepmc.org/articles/PMC6920543/
Autor:
Shiv Pillai, Jolan E. Walter, Jocelyn R. Farmer, Robert E. Gerszten, Hugues Allard-Chamard, Sara Barmettler, Samuel J.H. Murphy, Maimuna Ahmad, Vinay Mahajan, Mark D. Benson, Toby Aicher, Na Sun, Musie Ghebremichael, Alex K. Shalek, Grace J. Yuen, Facundo D. Batista, Alice Bertocchi, Johan Arnold, Jordan Morningstar
Publikováno v:
Sci Signal
Transitional B cells must actively undergo selection for self-tolerance before maturing into their resting follicular B cell successors. We found that metabolic quiescence was acquired at the follicular B cell stage in both humans and mice. In follic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2788d61f5921365480a902dd9bf8faa1
https://europepmc.org/articles/PMC7301641/
https://europepmc.org/articles/PMC7301641/
Autor:
Grace J, Yuen
Publikováno v:
Clin Immunol
In Western countries, about 5% of the population is affected by an autoimmune disease; in the United States, up to 23.5 million Americans suffer from autoimmune disorders(1). Women comprise over 80% of the affected individuals for many autoimmune con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8d41ffb7edc1d8dab7ebda49d8497796
https://pubmed.ncbi.nlm.nih.gov/31669190
https://pubmed.ncbi.nlm.nih.gov/31669190
Autor:
Shiv Pillai, Vinay Mahajan, James J. Moon, Johnson Q. Tran, Sudha Kumari, Ezana Demissie, Grace J. Yuen, Faisal Alsufyani, Darrell J. Irvine, Vinayak Viswanadham
The control of cytoskeletal dynamics by Dedicator of cytokinesis 2 (DOCK2), a hematopoietic cell-specific actin effector protein, has been implicated in TCR signaling and T cell migration. Biallelic mutations in Dock2 have been identified in patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff2c56cd5ed867e3351761167eb401f6