Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Grace Gosmann"'
Autor:
Aline Rigon Zimmer, Bianca Franco Leonardi, Eduardo Rigon Zimmer, Alexandre Pastoris Muller, Grace Gosmann, Luis Valmor Cruz Portela
Publikováno v:
Metabolites, Vol 13, Iss 3, p 385 (2023)
Metabolic syndrome is a serious health condition reaching epidemic proportions worldwide and is closely linked to an increased risk of cardiovascular problems. The lack of appropriate treatment paves the way for developing new therapeutic agents as a
Externí odkaz:
https://doaj.org/article/7c28dcbf0b434b9fbdc360811f66b515
Autor:
Bruna B. Casanova, Mauro N. Muniz, Thayse de Oliveira, Luís Flavio de Oliveira, Michel M. Machado, Alexandre M. Fuentefria, Grace Gosmann, Simone C. B. Gnoatto
Publikováno v:
Molecules, Vol 20, Iss 5, Pp 9229-9241 (2015)
Emerging yeasts are among the most prevalent causes of systemic infections with high mortality rates and there is an urgent need to develop specific, effective and non-toxic antifungal agents to respond to this issue. In this study 35 aldehydes, hydr
Externí odkaz:
https://doaj.org/article/996f7a8456d9409aae94f1811b1dc912
Autor:
Andréia Buffon, Simone C. B. Gnoatto, Guido Lenz, Eduardo C. F. Chiela, Scheron R. Giubel, Alessandra N. Bruno, Érica S. Maciel, Lucimara N. Comunello, Cristiane B. de Oliveira, Grace Gosmann
Publikováno v:
Molecules, Vol 18, Iss 9, Pp 11022-11032 (2013)
Baccharis trimera is used in folk medicine as a tea for digestive and liver diseases. It possesses anti-inflammatory and antioxidant properties that are related to the presence of phenolic compounds. The aim of this work was to investigate the anti-p
Externí odkaz:
https://doaj.org/article/fa3a9579d7264d82b1a657b8397bdcb1
Autor:
Simone C. B. Gnoatto, Célia R. S. Garcia, Grace Gosmann, Pascal Sonnet, Myna Nakabashi, Miriam S. Moraes, Laura Nogueira Cruz, Gloria N. S. Silva, Adrine M. Innocente
Publikováno v:
Molecules, Vol 17, Iss 10, Pp 12003-12014 (2012)
More than 40% of the World population is at risk of contracting malaria, which affects primarily poor populations in tropical and subtropical areas. Antimalarial pharmacotherapy has utilised plant-derived products such as quinine and artemisinin as w
Externí odkaz:
https://doaj.org/article/f0959674638f433a995977a74c424195
Phenolic Enriched Extract of Baccharis trimera Presents Anti-inflammatory and Antioxidant Activities
Autor:
Simone C. B. Gnoatto, Jarbas R. de Oliveira, Grace Gosmann, Vanusa Manfredini, Carmen Regla Vargas, Lucimara N. Comunello, Robson H. Amaral, Gabriela Lucas da Silva, Cristiane B. de Oliveira, Adroaldo Lunardelli, Melissa G. S. Pires
Publikováno v:
Molecules, Vol 17, Iss 1, Pp 1113-1123 (2012)
Baccharis trimera is a plant popularly used as a tea and to treat gastrointestinal diseases and inflammatory processes as well. The total phenolic content was determined and the antioxidant and anti-inflammatory activities of six extracts (dichlorome
Externí odkaz:
https://doaj.org/article/db0dbf27b5bb4a83848746de7c81844e
Autor:
Claiton L. Lencina, Mariana C. de Cardoso, Ivomar Zancanaro, Grace Gosmann, Viviane S. Pires, Pascal Sonnet, Dominique Guillaume, Eloir P. Schenkel
Publikováno v:
Química Nova, Vol 34, Iss 2, Pp 222-225 (2011)
Three saponins were isolated from leaves of Ilex chamaedryfolia. Their structures were established by spectroscopic and mass spectrometry data as the new saponin 3β-O-β-D-glucopyranosyl-(1-3)-α-L-arabinopyranosyl-20( S)-19α-hydroxyurs-12-en-28-oi
Externí odkaz:
https://doaj.org/article/e0581fe1ca0046549546d6a86aa378e4
Publikováno v:
Química Nova, Vol 32, Iss 5, Pp 1245-1252 (2009)
Oleanolic and ursolic acids are triterpenes that exist abundantly in the plant kingdom. They show antitumor activity and their cytotoxic activity was already evaluated against a broad range of cell lines. The inhibition of enzymes involved in the met
Externí odkaz:
https://doaj.org/article/1bcb305cccf045ae9a797c3547fe241f
Autor:
Fernanda de Costa, Anna Carolina A Yendo, Samuel P Cibulski, Juliane D Fleck, Paulo M Roehe, Fernando R Spilki, Grace Gosmann, Arthur G Fett-Neto
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105374 (2014)
Inactivated polio vaccines (IPV) have an important role at the final stages of poliomyelitis eradication programs, reducing the risks associated with the use of attenuated polio vaccine (OPV). An affordable option to enhance vaccine immunogenicity an
Externí odkaz:
https://doaj.org/article/2cc02b5e5e7242ec84b6318dd2c569a7
Autor:
Mariana Pies Gionbelli, Saulo Fernandes de Andrade, Marcela Silva Lopes, Grace Gosmann, Angélica Rocha Joaquim, Alexandre Meneghello Fuentefria
Publikováno v:
Journal of Medicinal Chemistry. 64:16349-16379
The search for new antimicrobials is imperative due to the emergent resistance of new microorganism strains. In this context, revisiting known classes like 8-hydroxyquinolines could be an interesting strategy to discover new agents. The 8-hydroxyquin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb4a71ad0f4cd265c84a642b4ae5942
https://doi.org/10.1021/acs.jmedchem.1c01318
https://doi.org/10.1021/acs.jmedchem.1c01318
Autor:
Aline Rigon Zimmer, Sergio T. Ferreira, Igor C. Fontana, Diogo O. Souza, Grace Gosmann, Andreia Silva da Rocha, Eduardo R. Zimmer, Mychael V. Lourenco
Publikováno v:
Journal of Neurochemistry. 155:348-369
Amyloid-β (Aβ) dysmetabolism is tightly associated with pathological processes in Alzheimer's disease (AD). Currently, it is thought that, in addition to Aβ fibrils that give rise to plaque formation, Aβ aggregates into non-fibrillar soluble olig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ae8dec1946ac81c75d88b1f1f45cc9
https://doi.org/10.1111/jnc.15030
https://doi.org/10.1111/jnc.15030