Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Grace Fu-Wan Sit"'
Autor:
Jacinth Wing-Sum Cheu, Derek Lee, Qidong Li, Chi Ching Goh, Macus Hao-Ran Bao, Vincent Wai-Hin Yuen, Misty Shuo Zhang, Chunxue Yang, Cerise Yuen-Ki Chan, Aki Pui-Wah Tse, Grace Fu-Wan Sit, Cindy Xinqi Liu, Irene Oi-Lin Ng, Chun-Ming Wong, Carmen Chak-Lui Wong
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 1, Pp 133-159 (2023)
Background & Aims: Hepatocellular carcinoma (HCC) is a highly aggressive malignancy with dreadful clinical outcome. Tyrosine kinase inhibitors and immune checkpoint inhibitors are the only United States Food and Drug Administration-approved therapeut
Externí odkaz:
https://doaj.org/article/23e349922f66486cae9f9e28d7a79df0
Autor:
Jacinth Wing-Sum Cheu, David Kung-Chun Chiu, Kenneth Kin-Leung Kwan, Chunxue Yang, Vincent Wai-Hin Yuen, Chi Ching Goh, Noreen Nog-Qin Chui, Wei Shen, Cheuk-Ting Law, Qidong Li, Misty Shuo Zhang, Macus Hao-Ran Bao, Bowie Po-Yee Wong, Cerise Yuen-Ki Chan, Cindy Xinqi Liu, Grace Fu-Wan Sit, Zher Yee Ooi, Haijing Deng, Aki Pui-Wah Tse, Irene Oi-Lin Ng, Carmen Chak-Lui Wong
Publikováno v:
Science Advances. 9
Hypoxia-induced adenosine creates an immunosuppressive tumor microenvironment (TME) and dampens the efficacy of immune checkpoint inhibitors (ICIs). We found that hypoxia-inducible factor 1 (HIF-1) orchestrates adenosine efflux through two steps in h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60e3d12590e8ef927219bb866c9ed471
https://doi.org/10.1126/sciadv.ade5111
https://doi.org/10.1126/sciadv.ade5111