Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Grace Forsyth"'
Autor:
Gabriele Matilionyte, Grace Forsyth, Jingtao Guo, Michael P. Rimmer, Brian P. Hermann, Richard A. Anderson, Rod T. Mitchell
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Currently there are no established fertility preservation options for pre-pubertal boys facing cancer treatment. Granulocyte-colony stimulating factor (G-CSF) treatment has been proposed to be chemoprotective against spermatogonia
Externí odkaz:
https://doaj.org/article/b30c250c7d104be2b459f638c8170cdc
Autor:
Denise Beaudequin, Adem T. Can, Megan Dutton, Monique Jones, Cyrana Gallay, Paul Schwenn, Cian Yang, Grace Forsyth, Gabrielle Simcock, Daniel F. Hermens, Jim Lagopoulos
Publikováno v:
BMC Psychiatry, Vol 20, Iss 1, Pp 1-15 (2020)
Abstract Background The glutamatergic modulator ketamine has been shown to result in rapid reductions in both suicidal ideation (SI) and depressive symptoms in clinical trials. There is a practical need for identification of pre-treatment predictors
Externí odkaz:
https://doaj.org/article/14d4e19fb87647c8bea0089221aac802
Treatment response with ketamine in chronic suicidality: An open label functional connectivity study
Autor:
Adem T. Can, Daniel F. Hermens, Abdalla Z. Mohamed, Zack Y. Shan, Megan Dutton, Cyrana Gallay, Grace Forsyth, Daniel Jamieson, Jim Lagopoulos
Publikováno v:
Journal of Affective Disorders. 331:92-100
Autor:
Megan Dutton, Adem T. Can, Denise Beaudequin, Emma Jensen, Monique Jones, Cyrana C. Gallay, Paul E. Schwenn, Jennifer K. Scherman, Cian Yang, Grace Forsyth, Jim Lagopoulos, Daniel F. Hermens
Publikováno v:
Journal of Affective Disorders. 300:410-417
Stress is prevalent in people experiencing suicidality and is a major contributor to the development of mental disorders. Evidence suggests ketamine shows capacity to reverse stress-induced brain changes. Though stress and ketamine have been explored
Autor:
Juan-Manuel Schvartzman, Grace Forsyth, Henry Walch, Walid Chatila, Anthony Santella, Kamal Menghrajani, Francisco Sánchez-Vega, Richard Koche, Craig B. Thompson
SummaryOncogenic mutations in the metabolic enzyme isocitrate dehydrogenase 1 and 2 (IDH1/2) have been found in a number of liquid and solid tumors. Their pathogenic mechanism of action involves production of 2-hydroxyglutarate (2HG), an oncometaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a9fad6de66368ad17ee885d249a7b74
https://doi.org/10.1101/2022.08.04.502834
https://doi.org/10.1101/2022.08.04.502834
Electrophysiological phenotypes of suicidality predict prolonged response to oral ketamine treatment
Autor:
Adem T. Can, Paul E. Schwenn, Ben Isbel, Denise Beaudequin, Ana P. Bouças, Megan Dutton, Monique Jones, Cyrana C. Gallay, Grace Forsyth, Maxwell R. Bennett, Jim Lagopoulos, Daniel F. Hermens
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 123
Oral ketamine has shown to be a rapid-acting antidepressant and a potential treatment option for suicidality, however, repeated doses are often required. Objective markers of prolonged treatment response are needed to help individuals and clinicians
Autor:
Juan Manuel Schvartzman, Grace Forsyth, Henry Walch, Walid Chatila, Anthony Santella, Kamal Menghrajani, Francisco Sanchez-Vega, Richard Koche, Craig Thompson
Publikováno v:
SSRN Electronic Journal.
Autor:
Gabrielle Simcock, Cyrana C. Gallay, Denise Beaudequin, Daniel F. Hermens, Grace Forsyth, Adem Can, Monique Jones, Megan Dutton, Paul E. Schwenn, Jim Lagopoulos, Cian Yang
Publikováno v:
BMC Psychiatry
BMC Psychiatry, Vol 20, Iss 1, Pp 1-15 (2020)
BMC Psychiatry, Vol 20, Iss 1, Pp 1-15 (2020)
Background The glutamatergic modulator ketamine has been shown to result in rapid reductions in both suicidal ideation (SI) and depressive symptoms in clinical trials. There is a practical need for identification of pre-treatment predictors of ketami
Autor:
Daniel F. Hermens, Megan Dutton, Emma Jensen, Daniel Jamieson, Jim Lagopoulos, Grace Forsyth, Adem Can, Max R. Bennett, Cyrana C. Gallay
Publikováno v:
Psychiatry Research: Neuroimaging. 317:111369
Chronic suicidality has been associated with neuronal atrophy in cortico-striato-limbic regions and is thought to be mediated via a glutamatergic imbalance. Ketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, has been posited to exert anti-
Autor:
Jennifer K. Scherman, Cyrana Gallay Grace Forsyth, Cian Yang, Megan Dutton, Jim Lagopoulos, Daniel F. Hermens, Denise Beaudequin, Adem Can, Emma Jensen, Paul E. Schwenn, Monique Jones
Publikováno v:
Psychiatry Research. 305:114212
Recovery of functioning is integral to successful treatment outcomes in depressive illness. Optimal antidepressant treatment results in both symptomatic remission and functional recovery. Oral ketamine rapidly reduces suicidality and depression; howe