Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Grace E, Peng"'
Publikováno v:
Nature chemical biology
G-protein-coupled receptor-regulated cAMP production from endosomes can specify signaling to the nucleus by moving the source of cAMP without changing its overall amount. How this is possible remains unknown because cAMP gradients dissipate over the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec152045b1062e7d187e9a23c1780e47
https://doi.org/10.1038/s41589-021-00747-0
https://doi.org/10.1038/s41589-021-00747-0
Autor:
Grace E, Peng, Mark, von Zastrow
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2483
Nuclear entry of cAMP-dependent protein kinase catalytic subunits is typically inferred from changes in net protein amount or kinase activity in the nucleus. Previous methods to directly assess nuclear entry require kinase subunit overexpression and/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::332c7d9799e850ab50e5849d23dd2475
https://pubmed.ncbi.nlm.nih.gov/35286686
https://pubmed.ncbi.nlm.nih.gov/35286686
Autor:
Grace E. Peng, Mark von Zastrow
Publikováno v:
cAMP Signaling ISBN: 9781071622445
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4ecc30e47f9a69dbf63ab46c98a053a
https://doi.org/10.1007/978-1-0716-2245-2_21
https://doi.org/10.1007/978-1-0716-2245-2_21
Autor:
Billy W. Newton, Michelle Trester-Zedlitz, Mark von Zastrow, Grace E. Peng, Nikoleta G. Tsvetanova, Jeffrey R. Johnson, Nevan J. Krogan, Andrew P. Kurland, David Jimenez-Morales
Publikováno v:
The Journal of Biological Chemistry
Endosomal signaling downstream of G-protein-coupled receptors (GPCRs) has emerged as a novel paradigm with important pharmacological and physiological implications. However, our knowledge of the functional consequences of intracellular signaling is i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::712684f871ff48f7eba6676f979b6239
http://europepmc.org/articles/PMC8294583
http://europepmc.org/articles/PMC8294583
Autor:
Mark von Zastrow, Billy W. Newton, Grace E. Peng, Michelle Trester-Zedlitz, Jeffrey R. Johnson, Nikoleta G. Tsvetanova, Nevan J. Krogan, David Jimenez-Morales
Endosomal signaling downstream of G protein-coupled receptors (GPCRs) has emerged as a novel paradigm with important pharmacological and physiological implications. Yet, our knowledge of the functional consequences of intracellular signaling is incom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eadbce09c51038ecfd8f4ca75e58191f
https://doi.org/10.1101/2021.01.06.425636
https://doi.org/10.1101/2021.01.06.425636
Publikováno v:
Nature Structural & Molecular Biology. 16:130-137
The elucidation of a code for regulated splicing has been a long-standing goal in understanding the control of post-transcriptional gene expression events that are crucial for cell survival, differentiation and development. We decoded functional RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ecab34d94167d3b351cf1802a569f8
https://doi.org/10.1038/nsmb.1545
https://doi.org/10.1038/nsmb.1545
Autor:
Fred H. Gage, Jose L. Garcia-Perez, Yangling Mu, Grace E. Peng, Maria C. Marchetto, Alysson R. Muotri, Nicole G. Coufal, Christian T. Carson, Angela Macia, John V. Moran
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 108(51)
Long interspersed element-1 (L1) retrotransposons compose ∼20% of the mammalian genome, and ongoing L1 retrotransposition events can impact genetic diversity by various mechanisms. Previous studies have demonstrated that endogenous L1 retrotranspos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c83d9722665aa53a5b39f47c42c66fa3
https://pubmed.ncbi.nlm.nih.gov/22159035
https://pubmed.ncbi.nlm.nih.gov/22159035
Autor:
Fred H. Gage, Nicole G. Coufal, K. Sue O'Shea, Gene W. Yeo, Michael T. Lovci, Jose L. Garcia-Perez, John V. Moran, Maria Morell, Yangling Mu, Grace E. Peng
Publikováno v:
Nature. 460(7259)
It is known that LINE-1 (long interspersed element-1) retrotransposons can move throughout the genomes of adult rat neural progenitor cells (NPCs) in vitro and in the mouse brain. Now it is shown that NPCs isolated from human fetal brain and derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22afc4c80a53c6753bc37184b69b4d3b
https://pubmed.ncbi.nlm.nih.gov/19713921
https://pubmed.ncbi.nlm.nih.gov/19713921