Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Grace Ciampa"'
Autor:
Jinxi Wang, Qian Shi, Yihui Wang, Logan W. Dawson, Grace Ciampa, Weiyang Zhao, Guangqin Zhang, Biyi Chen, Robert M. Weiss, Chad E. Grueter, Duane D. Hall, Long-Sheng Song
Publikováno v:
Circulation research. 130(9)
Background: Transcriptional remodeling is known to contribute to heart failure (HF). Targeting stress-dependent gene expression mechanisms may represent a clinically relevant gene therapy option. We recently uncovered a salutary mechanism in the hear
Autor:
E. Dale Abel, Qian Shi, Biyi Chen, Jinxi Wang, Tianqing Peng, Long-Sheng Song, Grace Ciampa, Dong Zheng, Duane D. Hall
Publikováno v:
Biochemical Journal
Calpain proteolysis contributes to the pathogenesis of heart failure but the calpain isoforms responsible and their substrate specificities have not been rigorously defined. One substrate, Junctophilin-2 (JP2), is essential for maintaining junctional