Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Grace C. Roberts"'
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Chikungunya virus (CHIKV), a mosquito-borne alphavirus, causes febrile disease, muscle and joint pain, which can become chronic in some individuals. The non-structural protein 3 (nsP3) plays essential roles during infection, but a complete u
Externí odkaz:
https://doaj.org/article/cfce921af4d1466292623637d73e7a2c
Autor:
Grace C Roberts, Paul G Morris, Marcus A Moss, Sarah L Maltby, Chelsea A Palmer, Claire E Nash, Emily Smart, Deborah L Holliday, Valerie Speirs
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157004 (2016)
BACKGROUND:3D cell cultures are emerging as more physiologically meaningful alternatives to monolayer cultures for many biological applications. They are attractive because they more closely mimic in vivo morphology, especially when co-cultured with
Externí odkaz:
https://doaj.org/article/fcf8b86f83a147cc8f4ce000a15fbabf
Autor:
Ultan F. Power, Michael D. Shields, Jonathon D. Coey, Judit Barabas, Lindsay Broadbent, Grace C. Roberts
Respiratory syncytial virus (RSV) infection is the leading cause of hospitalisation in children worldwide, but there is still no vaccine or anti-viral treatment available. RSV has been implicated in the development of respiratory diseases such as ast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::026574c144f17078218c4ec5e893327e
https://doi.org/10.1101/2021.11.22.469503
https://doi.org/10.1101/2021.11.22.469503
Autor:
Ultan F. Power, James McKenna, Conall McCaughey, Guillermo Lopez Campos, Grace C. Roberts, Ken I. Mills, Lindsay Broadbent, Olivier Touzelet, Elihu Aranday-Cortes, David Simpson, David G. Courtney, Connor G. G. Bamford, Mary McCabe, Derek Fairley, Ahlam A. Ali
SARS-CoV-2 continues to evolve, resulting in several ‘variants of concern’ with novel properties. The factors driving SARS-CoV-2 fitness and evolution in the human respiratory tract remain poorly defined. Here, we provide evidence that both viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f823f681b29033bc161258811938ea96
https://doi.org/10.1101/2021.07.16.452629
https://doi.org/10.1101/2021.07.16.452629
Is the ADP ribose site of the Chikungunya virus NSP3 Macro domain a target for antiviral approaches?
Autor:
Ana Carolina Gomes Jardim, Jacqueline Farinha Shimizu, Daniel Oliveira Silva Martins, Andres Merits, Mark Harris, Martin J. McPhillie, Grace C. Roberts, Carsten Zothner
Publikováno v:
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2020-12-10T17:35:32Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-07-01 Royal Society - Newton Advanced Fellowship Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Fundação de Amparo à Pes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e61c143136f24f6972e79430b8b57d89
https://pubmed.ncbi.nlm.nih.gov/32333884
https://pubmed.ncbi.nlm.nih.gov/32333884
The role of the chikungunya virus (CHIKV) non-structural protein 3 (nsP3) in the virus lifecycle is poorly understood. The protein comprises 3 domains. The N-terminus is a macro domain, biochemically characterised to bind both RNA and ADP-ribose, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a331471efa327523d6cde4d0cdc4e4e3
Publikováno v:
The Journal of General Virology
Hepatitis C virus (HCV) genotype (GT) 3 is the second most prevalent of the seven HCV genotypes and exhibits the greatest resistance to the highly potent, direct-acting antivirals (DAAs) that are currently in use. Previously a stable cell line harbou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ccbfca413ecd21b765ba7c6ff399c7df
https://pubmed.ncbi.nlm.nih.gov/28984238
https://pubmed.ncbi.nlm.nih.gov/28984238
Autor:
Grace C, Roberts, Paul G, Morris, Marcus A, Moss, Sarah L, Maltby, Chelsea A, Palmer, Claire E, Nash, Emily, Smart, Deborah L, Holliday, Valerie, Speirs
Publikováno v:
PLoS ONE
Background 3D cell cultures are emerging as more physiologically meaningful alternatives to monolayer cultures for many biological applications. They are attractive because they more closely mimic in vivo morphology, especially when co-cultured with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::20fff12096c8b686667782eb55267ced
https://pubmed.ncbi.nlm.nih.gov/27300768
https://pubmed.ncbi.nlm.nih.gov/27300768