Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Grace C Verzosa"'
Autor:
Carolyn M. Roos, Bin Zhang, Michael A. Hagler, Grace C. Verzosa, Runqing Huang, Elise A. Oehler, Arman Arghami, Jordan D. Miller
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: While a small number of studies suggest that oxidative stress has an influential role in fibrocalcific aortic valve disease (FCAVD), the roles of specific antioxidant enzymes in progression of this disease remain poorly understood. Here,
Externí odkaz:
https://doaj.org/article/b957ad7c970048dcb72e78e450e48273
Autor:
Nobuyuki Kagiyama, Naveena Yanamala, Sandeep Banga, Sirish Shrestha, Grace C. Verzosa, Partho P. Sengupta
Publikováno v:
Journal of the American College of Cardiology. 79:30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c11dbd7b63b30992ebf49905abdd44b
https://doi.org/10.1016/s0735-1097(22)01021-x
https://doi.org/10.1016/s0735-1097(22)01021-x
Autor:
Vesselina M. Pearsall, Nathan K. LeBrasseur, Daniel L. Mazula, Marissa J. Schafer, Jordan D. Miller, Thomas A. White, Ashley K. Brown, Zaira Aversa, Aleksey V. Matveyenko, Grace C Verzosa, Elizabeth J. Atkinson, Leslie A. Smith
Publikováno v:
Aging Cell
Aging and obesity increase multimorbidity and disability risk, and determining interventions for reversing healthspan decline is a critical public health priority. Exercise and time‐restricted feeding (TRF) benefit multiple health parameters when i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e18a1c2683ecfbe99126b3c59675e90
https://doi.org/10.1111/acel.12966
https://doi.org/10.1111/acel.12966
Autor:
Arman Arghami, Michael A Hagler, Jordan D. Miller, Bin Zhang, Elise A. Oehler, Grace C Verzosa, Carolyn M Roos
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
The balance between local asymmetric dimethylarginine (ADMA) levels and dimethylarginine dimethylaminohydrolase 1 (DDAH1) activity is a major determinant of local nitric oxide synthase activity. Previous studies suggested that increased plasma ADMA l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb70168419e7c3ce50240a5116d29c2b
https://doi.org/10.1161/atvb.38.suppl_1.238
https://doi.org/10.1161/atvb.38.suppl_1.238
Autor:
Bettina M. Weigand, Christine M Hachfeld, Ming Xu, Joshua N. Farr, Xiaonan Hou, Vesna D. Garovic, Jennifer L Onken, Larissa G.P. Langhi, Tamar Pirtskhalava, Hajrunisa Cubro, Ravinder J. Singh, S. John Weroha, Megan M. Weivoda, Mikolaj Ogrodnik, Kurt O. Johnson, Keisuke Ejima, Gene B. Hubbard, Laura J. Niedernhofer, Grace C Verzosa, Diana Jurk, James L. Kirkland, Paul D. Robbins, Moritz Weigl, Christina L. Inman, Jordan D. Miller, Daniel G. Fraser, David B. Allison, Nino Giorgadze, Sundeep Khosla, Yuji Ikeno, Allyson K. Palmer, Tamara Tchkonia, Nathan K. LeBrasseur
Publikováno v:
Nature medicine
Physical function declines in old age, portending disability, increased health expenditures, and mortality. Cellular senescence, leading to tissue dysfunction, may contribute to these consequences of aging, but whether senescence can directly drive a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02db7172651264fd5240a5fe961df9ae
https://pubmed.ncbi.nlm.nih.gov/30292430
https://pubmed.ncbi.nlm.nih.gov/30292430
Autor:
Rebecca L Black, Carolyn M Roos, Michael A Hagler, Nassir M Thalji, Bin Zhang, Grace C Verzosa, Jordan D Miller
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Marfan syndrome is a connective tissue disorder frequently driven by mutations in the fibrillin-1 gene (Fbn1). This results in multiple aberrant cardiovascular phenotypes, including aortic aneurysm and mitral valve prolapse. While the molecular chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b8540997d2ef6a9b5848c7edbac46f5
https://doi.org/10.1161/atvb.37.suppl_1.249
https://doi.org/10.1161/atvb.37.suppl_1.249
Autor:
Carolyn M Roos, Michael A Hagler, Grace C Verzosa, Bin Zhang, Hirokazu Fujimoto, Jordan D Miller
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Increasing age is the greatest risk factor for development and progression of calcific aortic valve disease (CAVD), and mitochondrial dysfunction has been implicated in the pathogenesis of cardiovascular calcification. Previous findings by our group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::357de88a4827acba3df3bf34b9cdced3
https://doi.org/10.1161/atvb.37.suppl_1.427
https://doi.org/10.1161/atvb.37.suppl_1.427
Autor:
Cynthia J. Sieben, Khashayarsha Khazaie, Abdulmohammad Pezeshki, Jian Zhong, Rachel A. Saltness, Matej Durik, Karthik B. Jeganathan, Melinde Wijers, Darren J. Baker, Bennett G. Childs, Jan M. van Deursen, Grace C Verzosa, Jordan D. Miller
Publikováno v:
Nature, 530, 184-9
Nature, 530, 7589, pp. 184-9
Nature, 530, 7589, pp. 184-9
Item does not contain fulltext Cellular senescence, a stress-induced irreversible growth arrest often characterized by expression of p16(Ink4a) (encoded by the Ink4a/Arf locus, also known as Cdkn2a) and a distinctive secretory phenotype, prevents the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80ab943c3aa7f6d1dc8108fe08565173
http://hdl.handle.net/2066/171025
http://hdl.handle.net/2066/171025
Autor:
Allyson K. Palmer, Michael D. Jensen, Marissa J. Schafer, Michael Torbenson, Jason M. Tonne, Michael B. Stout, Thomas A. White, Glenda L. Evans, Jan M. van Deursen, Tamara Tchkonia, James L. Kirkland, Jordan D. Miller, Daniel L. Mazula, Nathan K. LeBrasseur, Grace C Verzosa, Darren J. Baker, Yasuhiro Ikeda
Publikováno v:
Diabetes, 65, 6, pp. 1606-15
Diabetes, 65, 1606-15
Diabetes
Diabetes, 65, 1606-15
Diabetes
Item does not contain fulltext Considerable evidence implicates cellular senescence in the biology of aging and chronic disease. Diet and exercise are determinants of healthy aging; however, the extent to which they affect the behavior and accretion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adce1a84d886358ff1e4a28a99e8d858
https://hdl.handle.net/2066/172511
https://hdl.handle.net/2066/172511
Autor:
Márton Tokodi, Mokoto Amaki, Grace C Verzosa, Muhammad Ashraf, Haruhiko Abe, Ali Amin, Sirish Shrestha, Partho P. Sengupta
Publikováno v:
Journal of the American College of Cardiology. 71:A1659
Recent investigations suggest a strong relation between cardiovascular diseases and blood flow patterns such as vortices. Clinical imaging of vortices is based upon manual extraction where flow fields are classified according to specific, unstandardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85cff8a7ea0fd804f6f1547267b773d5
https://doi.org/10.1016/s0735-1097(18)32200-9
https://doi.org/10.1016/s0735-1097(18)32200-9