Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Grace Bigham"'
Publikováno v:
MedEdPORTAL, Vol 18 (2022)
Introduction Social determinants of health (SDHs) are now recognized as a major factor affecting patient health outcomes and should be addressed by the health care system. Many medical students do not receive practical training on how to assess SDH n
Externí odkaz:
https://doaj.org/article/7436e115333b4a04818e305b848e584a
Publikováno v:
Journal of the American College of Cardiology. 81:3801
Publikováno v:
MedEdPORTAL : the journal of teaching and learning resources. 18
Social determinants of health (SDHs) are now recognized as a major factor affecting patient health outcomes and should be addressed by the health care system. Many medical students do not receive practical training on how to assess SDH needs or conne
Autor:
William A. Ravekes, Brody Wehman, Casey Naughton, Nicholas Pietris, Allen D. Everett, Søren M. Bentzen, Sudhish Sharma, Helina Mehta, Aisha Khan, Darcy L. DiFede, Rachana Mishra, Sunjay Kaushal, Luca A. Vricella, Grace Bigham, Joshua M. Hare, Kristopher B. Deatrick, Sihong Huang, Naru Hibino
Publikováno v:
American Heart Journal. 192:48-56
Despite advances in surgical technique and postoperative care, long-term survival of children born with hypoplastic left heart syndrome (HLHS) remains limited, with cardiac transplantation as the only alternative for patients with failing single vent
Autor:
Sudhish Sharma, Prashanth Vallabhajosyula, Deqiang Li, Chetan Ambastha, Srinivasa Raju Datla, Andreas Habertheuer, Gregory J. Bittle, Grace Bigham, Sunjay Kaushal, Muthukumar Gunasekaran, Rachana Mishra, Robert W. Hu, Farnaz Shoja-Taheri, David L.S. Morales, Mir Yasir Arfat, Peixin Yang, Progyaparamita Saha, Manu O. Platt, Laxminarayana Korutla, Malini Sarkar, Michael Davis
Publikováno v:
Sci Transl Med
The stem cell field is hindered by its inability to noninvasively monitor transplanted cells within the target organ in a repeatable, time-sensitive, and condition-specific manner. We hypothesized that quantifying and characterizing transplanted cell
Autor:
Osama T. Siddiqui, Brody Wehman, Emily Aiello, Nicholas Pietris, Rachana Mishra, Sudhish Sharma, Mark F. Pittenger, Sarah B. Murthi, Grace Bigham, Sunjay Kaushal, Tieluo Li, Bartley P. Griffith
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 310:H1816-H1826
Limited therapies exist for patients with congenital heart disease (CHD) who develop right ventricular (RV) dysfunction. Bone marrow-derived mesenchymal stem cells (MSCs) have not been evaluated in a preclinical model of pressure overload, which simu
Autor:
Muthukumar Gunasekaran, Chetan Ambastha, Phillip Z Brohawn, Sudhish Sharma, Sunjay Kaushal, Grace Bigham, Sotirios K. Karathanasis
Publikováno v:
Circulation Research. 123
Background: We identified that human neonatal cardiac progenitor cells (CPCs) improve cardiac function and attenuate adverse left ventricular remodeling after myocardial infarction through their exosomes (nEXOs). RNAseq analysis of nEXOs identified m
Autor:
Sudhish Sharma, Grace Bigham, Progyaparamita Saha, Rachana Mishra, Sonia Draggulin-Otto, Philip Zachary-Brohawn, Laxminarayan Korutla, Prashanth Vallabhajosyula, Sotirios Karathanasis, Sunjay Kaushal
Publikováno v:
Circulation. 136
Introduction: Cardiac Progenitor cells (CPCs, identified by ckit+/CD45-/lin-) are being used in 21 clinical trials (recruiting and completed) to restore heart function and promote tissue regeneration in response to injury and their exosomes (EXO) has
Autor:
Sotirios K. Karathanasis, Sunjay Kaushal, Rachana Mishra, Peixin Yang, Grace Bigham, Progyaparamita Saha, Ling Chen, Brody Wehman, Mohan E. Tulapurkar, Young Ah Goo, Srinivasa Raju Datla, Sudhish Sharma, Mohd M. Khan, David R. Goodlett, Bradley S. Taylor, Huichun Xu
Rationale: Cardiac progenitor cells are an attractive cell type for tissue regeneration, but their mechanism for myocardial remodeling is still unclear. Objective: This investigation determines how chronological age influences the phenotypic characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f684f203d4986ffeb64f3823a116a271
https://europepmc.org/articles/PMC5834230/
https://europepmc.org/articles/PMC5834230/
Autor:
Nicholas Pietris, Wendy Wang, Sudhish Sharma, Grace Bigham, Osama T. Siddiqui, Sunjay Kaushal, Tieluo Li, Brody Wehman, Sarah B. Murthi, Godly Jack, Emily Aiello, Rachana Mishra
Publikováno v:
The Annals of thoracic surgery. 104(6)
Background C-kit + cardiac progenitor cells (CPCs) have been shown to be safe and effective in large-animal models and in an early-phase clinical trial for adult patients with ischemic heart disease. However, CPCs have not yet been evaluated in a pre