Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Grace A. Hernandez"'
Autor:
Joyce V. Lee, Filomena Housley, Christina Yau, Rachel Nakagawa, Juliane Winkler, Johanna M. Anttila, Pauliina M. Munne, Mariel Savelius, Kathleen E. Houlahan, Daniel Van de Mark, Golzar Hemmati, Grace A. Hernandez, Yibing Zhang, Susan Samson, Carole Baas, Laura J. Esserman, Laura J. van ‘t Veer, Hope S. Rugo, Christina Curtis, Juha Klefström, Mehrdad Matloubian, Andrei Goga
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The oncoprotein c-Myc is often overexpressed in triple negative breast cancer and has a role in tumor progression and resistance to therapy. Here the authors show that elevated MYC expression is correlated with low immune infiltration, diminished MHC
Externí odkaz:
https://doaj.org/article/5ba305a5a1f9497c9247af3f00c75bef
Autor:
Dennis Ma, Grace A. Hernandez, Austin E. Y. T. Lefebvre, Hamad Alshetaiwi, Kerrigan Blake, Kushal R. Dave, Maha Rauf, Justice W. Williams, Ryan T. Davis, Katrina T. Evans, Aaron Longworth, Madona Y. G. Masoud, Regis Lee, Robert A. Edwards, Michelle A. Digman, Kai Kessenbrock, Devon A. Lawson
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Ma, Hernandez et al develop a 3D culture-transplant system to enable studies of cancer metastasis using patient-derived xenograft (PDX) tumor cells. Using this system, they find that OXPHOS inhibition attenuates the lung metastatic capacity of breast
Externí odkaz:
https://doaj.org/article/b3b006f381d643aa8b2f8e3e8294d505
Autor:
Joyce V. Lee, Filomena Housley, Christina Yau, Rachel Nakagawa, Juliane Winkler, Johanna M. Anttila, Pauliina M. Munne, Mariel Savelius, Kathleen E. Houlahan, Daniel Van de Mark, Golzar Hemmati, Grace A. Hernandez, Yibing Zhang, Susan Samson, Carole Baas, Marleen Kok, Laura J. Esserman, Laura J. van ‘t Veer, Hope S. Rugo, Christina Curtis, Juha Klefström, Mehrdad Matloubian, Andrei Goga
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/c4c95fa626f54c138a7df8b82c363e2c
Autor:
Grace A. Hernandez, Rushika M. Perera
Publikováno v:
Mol Cell
Molecular cell, vol 82, iss 8
Molecular cell, vol 82, iss 8
As one of the two highly conserved cellular degradation systems, autophagy plays a critical role in regulation of protein, lipid, and organelle quality control and cellular homeostasis. This evolutionarily conserved pathway singles out intracellular
Autor:
Ryan T. Davis, Grace A. Hernandez, Michelle A. Digman, Kushal R. Dave, Aaron Longworth, Devon A. Lawson, Kerrigan Blake, Justice W. Williams, Hamad Alshetaiwi, Katrina Evans, Regis Lee, Maha Rauf, Dennis Ma, Madona Y.G. Masoud, Robert Edwards, Austin E. Y. T. Lefebvre, Kai Kessenbrock
Publikováno v:
Communications biology, vol 4, iss 1
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications Biology
Metastasis is a fatal disease where research progress has been hindered by a lack of authentic experimental models. Here, we develop a 3D tumor sphere culture-transplant system that facilitates the growth and engineering of patient-derived xenograft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc1c9d48e143558dd1afa25db56c5c42
https://escholarship.org/uc/item/4489t47r
https://escholarship.org/uc/item/4489t47r
Autor:
Kai Kessenbrock, Dennis Ma, Justice W. Williams, Qing Nie, Quy H. Nguyen, Anush Markaryan, Robert Edwards, Kushal R. Dave, Yanwen Gong, Ritesh Parajuli, Nicholas Pervolarakis, Grace A. Hernandez, Maha Rauf, Christian Calderon, Maren Pein, Sundus Shalabi, Jacob Insua-Rodríguez, Kevin Nee, Hamad Alshetaiwi, Keerti Boyapati, Erin Lin, Mark A. LaBarge, Peijie Zhou
SummaryWomen with germline mutations in BRCA1 (BRCA1+/mut) have increased risk for developing hereditary breast cancer1, 2. Cancer initiation in BRCA1+/mut is associated with pre-malignant changes in the breast epithelium including altered differenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1dce99d86c30481daf1bafd5cbdb389
https://doi.org/10.1101/2021.10.20.465221
https://doi.org/10.1101/2021.10.20.465221
Autor:
Roselito E. Tolentino, Janielle D. Antiporta, Carlo G. Coste, Ariane Grace B. Hernandez, John Carlos H. Garro, Mariela A. Pasamba
Publikováno v:
2021 IEEE Madras Section Conference (MASCON).
The study aimed to apply the Microsoft Kinect for Xbox One with the use of Convolution Neural Network and Adaptive Boosting to be able to recognize the hazardous object and threatening gestures. Microsoft Kinect for XBOX One and Visual Gesture Builde
Autor:
Rachel Nakagawa, Yibing Zhang, Joyce V. Lee, Filomena Housley, Carole Baas, Daniel Van de Mark, Susan Samson, Laura J. van't Veer, Golzar Hemmati, Mehrdad Matloubian, Grace A. Hernandez, Laura J. Esserman, Juliane Winkler, Andrei Goga, Hope S. Rugo, Christina Yau
For many human cancers, including triple negative breast cancer (TNBC), a modest number of patients benefit from immune checkpoint inhibitors, and few experience cancer remission1. Expression of programed death-ligand 1 (PD-L1), tumor immune infiltra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96ef66abcc1f9601a37b22188d5d307c
https://doi.org/10.1101/2021.05.07.442684
https://doi.org/10.1101/2021.05.07.442684
Autor:
Dennis Ma, Kerrigan Blake, Grace A. Hernandez, Devon A. Lawson, Austin E.Y.T. Lefebvre, Michelle A. Digman, Kai Kessenbrock, Katrina T. Evans, Maha Rauf, Justice W. Williams, Hamad Alshetaiwi, Kushal R. Dave, Ryan T. Davis, Madona Y.G. Masoud, Regis Lee, Robert A. Edwards
Metastasis is a fatal disease where research progress has been hindered by a lack of authentic experimental models. Here, we develop a 3D tumor sphere culture-transplant system that facilitates the expansion and engineering of patient-derived xenogra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::280a26d66dc40d46bd3a7dfbb0fcf59e
https://doi.org/10.1101/2020.06.25.172056
https://doi.org/10.1101/2020.06.25.172056
Autor:
Grace A. Hernandez, Kevin Nee, Katrina Evans, Hamad Alshetaiwi, Dennis Ma, Leona Torosian, Laura L. McIntyre, Jan A. Rath, Craig M. Walsh, Nicholas Pervolarakis, Kai Kessenbrock, Quy H. Nguyen, Anushka Silva
Publikováno v:
Science immunology, vol 5, iss 44
Sci Immunol
Sci Immunol
Myeloid-derived suppressor cells (MDSCs) are innate immune cells that acquire the capacity to suppress adaptive immune responses during cancer. It remains elusive how MDSCs differ from their normal myeloid counterparts, which limits our ability to sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::410dc051e6d61471f060c9673ea61193
https://escholarship.org/uc/item/0k8003jg
https://escholarship.org/uc/item/0k8003jg