Zobrazeno 1 - 10
of 321
pro vyhledávání: '"Grace A, McComsey"'
Autor:
Nicholas T. Funderburg, Susie S. Y. Huang, Calvin Cohen, Kate Ailstock, Morgan Cummings, Jean C. Lee, Brenda Ng, Kirsten White, Jeffrey J. Wallin, Bryan Downie, Grace A. McComsey
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundHeightened levels of inflammatory markers are linked to increased morbidity/mortality in people with HIV (PWH) and often remain elevated after virologic suppression by antiretroviral therapy (ART). As new combinations of ART become availabl
Externí odkaz:
https://doaj.org/article/4c70560a0cfa454db03d0fbb5ef429d1
Autor:
Al Ozonoff, Naresh Doni Jayavelu, Shanshan Liu, Esther Melamed, Carly E. Milliren, Jingjing Qi, Linda N. Geng, Grace A. McComsey, Charles B. Cairns, Lindsey R. Baden, Joanna Schaenman, Albert C. Shaw, Hady Samaha, Vicki Seyfert-Margolis, Florian Krammer, Lindsey B. Rosen, Hanno Steen, Caitlin Syphurs, Ravi Dandekar, Casey P. Shannon, Rafick P. Sekaly, Lauren I. R. Ehrlich, David B. Corry, Farrah Kheradmand, Mark A. Atkinson, Scott C. Brakenridge, Nelson I. Agudelo Higuita, Jordan P. Metcalf, Catherine L. Hough, William B. Messer, Bali Pulendran, Kari C. Nadeau, Mark M. Davis, Ana Fernandez Sesma, Viviana Simon, Harm van Bakel, Seunghee Kim-Schulze, David A. Hafler, Ofer Levy, Monica Kraft, Chris Bime, Elias K. Haddad, Carolyn S. Calfee, David J. Erle, Charles R. Langelier, Walter Eckalbar, Steven E. Bosinger, IMPACC Network, Bjoern Peters, Steven H. Kleinstein, Elaine F. Reed, Alison D. Augustine, Joann Diray-Arce, Holden T. Maecker, Matthew C. Altman, Ruth R. Montgomery, Patrice M. Becker, Nadine Rouphael
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Post-acute sequelae of SARS-CoV-2 (PASC) is a significant public health concern. We describe Patient Reported Outcomes (PROs) on 590 participants prospectively assessed from hospital admission for COVID-19 through one year after discharge. M
Externí odkaz:
https://doaj.org/article/ec0ddc29cd90460ca1ec27bea2b831b8
Autor:
Jared C. Durieux, Sokratis N. Zisis, Christian Mouchati, Danielle Labbato, Marc Abboud, Grace A. McComsey
Publikováno v:
Viruses, Vol 16, Iss 7, p 1089 (2024)
There is limited long-term evidence on the effects of COVID-19 on vascular injury between male and female sex. An adult cohort of COVID-19 survivors (COVID+) and confirmed SARS-CoV-2 antibody-negative participants (COVID-) were prospectively enrolled
Externí odkaz:
https://doaj.org/article/617edbb55fe048c8846a6121604a6efc
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionSevere acute respiratory syndrome coronavirus-2 (SARS-CoV-2) may trigger autoimmune disease (AD) through initial innate immune activation with subsequent aberrations in adaptive immune cells leading to AD. While there are multiple reports
Externí odkaz:
https://doaj.org/article/07b03296e0254dcfb327a9271e7bcb99
Autor:
Elaine J Abrams, Jennifer Jao, Hlengiwe P Madlala, Allison Zerbe, Patrick Catalano, Mariana Gerschenson, Julia H Goedecke, Yolanda Gomba, Jami Josefson, Irwin J Kurland, Justine Legbedze, Grace A McComsey, Sandisiwe Matyesini, Elton Mukonda, Daniel Robinson, Landon Myer
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0307296 (2024)
IntroductionDolutegravir (DTG)-based antiretroviral therapy is the World Health Organization's preferred first-line regimen for all persons with HIV, including pregnant women. While DTG has been implicated as an obesogen associated with greater weigh
Externí odkaz:
https://doaj.org/article/bc5b86ee83da4a9c8e8422540cc89115
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPeople with HIV (PWH) are at higher risk of complications from acute COVID-19, but their risk of subsequent post-acute sequelae of SARS-CoV2 (PASC) remains unclear. Although vaccination is protective of PASC among survivors in the general p
Externí odkaz:
https://doaj.org/article/55bab99284d74a72a10cbe109304ccba
Autor:
Terry F Plasse, Belkis Delgado, Jeffrey Potts, Danielle Abramson, Clara Fehrmann, Reza Fathi, Grace A McComsey
Publikováno v:
International Journal of Infectious Diseases, Vol 128, Iss , Pp 148-156 (2023)
Objectives: We performed a pilot study of upamostat, a serine protease inhibitor, in outpatients with symptomatic COVID-19 before a pivotal trial. Methods: SARS-CoV-2 patients with ≥2 moderate-severe symptoms onset within 5 days were randomized to
Externí odkaz:
https://doaj.org/article/d6b8d059fd41475e8822d724894bbf91
Autor:
Charlotte Hedskog, Christoph D. Spinner, Ulrike Protzer, Dieter Hoffmann, Chunkyu Ko, Robert L. Gottlieb, Medhat Askar, Meta Roestenberg, Jutte J. C. de Vries, Ellen C. Carbo, Ross Martin, Jiani Li, Dong Han, Lauren Rodriguez, Aiyappa Parvangada, Jason K. Perry, Ricard Ferrer, Andrés Antón, Cristina Andrés, Vanessa Casares, Huldrych F. Günthard, Michael Huber, Grace A. McComsey, Navid Sadri, Judith A. Aberg, Harm van Bakel, Danielle P. Porter
Publikováno v:
Viruses, Vol 16, Iss 4, p 546 (2024)
Remdesivir (RDV) is a broad-spectrum nucleotide analog prodrug approved for the treatment of COVID-19 in hospitalized and non-hospitalized patients with clinical benefit demonstrated in multiple Phase 3 trials. Here we present SARS-CoV-2 resistance a
Externí odkaz:
https://doaj.org/article/96f39a75be5a4ab7bceddaed4be70324
Autor:
Lechuang Chen, Rui Chen, Min Yao, Zhimin Feng, Guoxiang Yuan, Fengchun Ye, Kien Nguyen, Jonathan Karn, Grace A. McComsey, Thomas M. McIntyre, Ge Jin
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Elevated serum cytokine production in COVID-19 patients is associated with disease progression and severity. However, the stimuli that initiate cytokine production in patients remain to be fully revealed. Virus-infected cells release virus-a
Externí odkaz:
https://doaj.org/article/a451518cb9a9498c9ed91d7140d9f142
Autor:
Christian Mouchati, Jared C. Durieux, Sokratis N. Zisis, Danielle Labbato, Michael A. Rodgers, Kate Ailstock, Brian L. Reinert, Nicholas T. Funderburg, Grace A. McComsey
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundPost-acute sequelae of SARS-CoV-2 (PASC) is marked by persistent or newly developing symptoms beyond 4 weeks of infection. Investigating gut integrity, oxidized lipids and inflammatory markers is important for understanding PASC pathogenesi
Externí odkaz:
https://doaj.org/article/d9cf064a67a34bddb80041cc9f6a2e7a