Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Grabowsky, JA"'
Autor:
Munster, Pamela, Bergsland, Emily, Kelley, Robin Kate, Bendell, JC, Kelley, RK, Shih, KC, Grabowsky, JA, Jones, S, Martin, T, Infante, JR, Mischel, PS, Matsutani, T
Publikováno v:
Munster, Pamela; Bergsland, Emily; Kelley, Robin Kate; Bendell, JC; Kelley, RK; Shih, KC; et al.(2015). A phase i dose-escalation study to assess safety, tolerability, pharmacokinetics, and preliminary efficacy of the dual mTORC1/mTORC2 kinase inhibitor CC-223 in patients with advanced solid tumors or multiple myeloma. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/9sq7h6jn
© 2015 American Cancer Society.BACKGROUND The mammalian target of rapamycin (mTOR) pathway is essential for tumor development, yet mTOR inhibitors have yielded modest results. This phase 1 study investigated the mTORC1/mTORC2 inhibitor CC-223 in pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::fb775ecc20d69b0d8a5e91c37bed7555
http://www.escholarship.org/uc/item/9sq7h6jn
http://www.escholarship.org/uc/item/9sq7h6jn
Autor:
Dhawan MS; University of California, San Francisco, San Francisco, CA., Bartelink IH; University of California, San Francisco, San Francisco, CA., Aggarwal RR; University of California, San Francisco, San Francisco, CA., Leng J; University of California, San Francisco, San Francisco, CA., Zhang JZ; University of California, San Francisco, San Francisco, CA., Pawlowska N; University of California, San Francisco, San Francisco, CA., Terranova-Barberio M; University of California, San Francisco, San Francisco, CA., Grabowsky JA; University of California, San Francisco, San Francisco, CA., Gewitz A; University of California, San Francisco, San Francisco, CA., Chien AJ; University of California, San Francisco, San Francisco, CA., Moasser M; University of California, San Francisco, San Francisco, CA., Kelley RK; University of California, San Francisco, San Francisco, CA., Maktabi T; University of California, San Francisco, San Francisco, CA., Thomas S; University of California, San Francisco, San Francisco, CA., Munster PN; University of California, San Francisco, San Francisco, CA. pamela.munster@ucsf.edu.
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2017 Nov 01; Vol. 23 (21), pp. 6400-6410. Date of Electronic Publication: 2017 Aug 08.
Autor:
Thomas S; Department of Medicine/Hematology and Oncology, University of California, San Francisco, San Francisco, USA., Aggarwal R; Department of Medicine/Hematology and Oncology, University of California, San Francisco, San Francisco, USA., Jahan T; Department of Medicine/Hematology and Oncology, University of California, San Francisco, San Francisco, USA., Ryan C; Department of Medicine/Hematology and Oncology, University of California, San Francisco, San Francisco, USA., Troung T; Department of Medicine/Hematology and Oncology, University of California, San Francisco, San Francisco, USA., Cripps AM; Department of Medicine/Hematology and Oncology, University of California, San Francisco, San Francisco, USA., Raha P; Department of Medicine/Hematology and Oncology, University of California, San Francisco, San Francisco, USA., Thurn KT; Department of Medicine/Hematology and Oncology, University of California, San Francisco, San Francisco, USA., Chen S; Department of Medicine/Hematology and Oncology, University of California, San Francisco, San Francisco, USA., Grabowsky JA; Department of Medicine/Hematology and Oncology, University of California, San Francisco, San Francisco, USA., Park J; Department of Medicine/Hematology and Oncology, University of California, San Francisco, San Francisco, USA., Hwang J; Department of Medicine/Hematology and Oncology, University of California, San Francisco, San Francisco, USA., Daud A; Department of Medicine/Hematology and Oncology, University of California, San Francisco, San Francisco, USA., Munster PN; Department of Medicine/Hematology and Oncology, University of California, San Francisco, San Francisco, USA pamela.munster@ucsf.edu.
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2016 May; Vol. 27 (5), pp. 947-52. Date of Electronic Publication: 2016 Feb 21.
Autor:
Bendell JC; Sarah Cannon Research Institute, Nashville, Tennessee., Kelley RK; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California., Shih KC; Sarah Cannon Research Institute, Nashville, Tennessee., Grabowsky JA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California., Bergsland E; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California., Jones S; Sarah Cannon Research Institute, Nashville, Tennessee., Martin T; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California., Infante JR; Sarah Cannon Research Institute, Nashville, Tennessee., Mischel PS; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, California., Matsutani T; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, California., Xu S; Celgene Corporation, San Diego, California., Wong L; Celgene Corporation, San Diego, California., Liu Y; Celgene Corporation, Summit, New Jersey., Wu X; Celgene Corporation, Berkeley Heights, New Jersey., Mortensen DS; Celgene Corporation, San Diego, California., Chopra R; Celgene Corporation, Summit, New Jersey., Hege K; Celgene Corporation, San Francisco, California., Munster PN; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California.
Publikováno v:
Cancer [Cancer] 2015 Oct 01; Vol. 121 (19), pp. 3481-90. Date of Electronic Publication: 2015 Jul 15.
Autor:
Daud AI; Adil I. Daud, Michelle T. Ashworth, Alan P. Venook, Jennifer A. Grabowsky, and Pamela N. Munster, University of California, San Francisco, San Francisco; Jonathan W. Goldman and Lee S. Rosen, University of California, Los Angeles, Santa Monica, CA; Jonathan Strosberg and Gregory Springett, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; David Mendelson, Pinnacle Oncology Hematology, Scottsdale, AZ; and Sabine Loechner, Frances Shanahan, David Parry, Stuart Shumway, Tomoko Freshwater, Christopher Sorge, Soonmo Peter Kang, and Randi Isaacs, Merck, Whitehouse Station, NJ. adaud@medicine.ucsf.edu., Ashworth MT; Adil I. Daud, Michelle T. Ashworth, Alan P. Venook, Jennifer A. Grabowsky, and Pamela N. Munster, University of California, San Francisco, San Francisco; Jonathan W. Goldman and Lee S. Rosen, University of California, Los Angeles, Santa Monica, CA; Jonathan Strosberg and Gregory Springett, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; David Mendelson, Pinnacle Oncology Hematology, Scottsdale, AZ; and Sabine Loechner, Frances Shanahan, David Parry, Stuart Shumway, Tomoko Freshwater, Christopher Sorge, Soonmo Peter Kang, and Randi Isaacs, Merck, Whitehouse Station, NJ., Strosberg J; Adil I. Daud, Michelle T. Ashworth, Alan P. Venook, Jennifer A. Grabowsky, and Pamela N. Munster, University of California, San Francisco, San Francisco; Jonathan W. Goldman and Lee S. Rosen, University of California, Los Angeles, Santa Monica, CA; Jonathan Strosberg and Gregory Springett, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; David Mendelson, Pinnacle Oncology Hematology, Scottsdale, AZ; and Sabine Loechner, Frances Shanahan, David Parry, Stuart Shumway, Tomoko Freshwater, Christopher Sorge, Soonmo Peter Kang, and Randi Isaacs, Merck, Whitehouse Station, NJ., Goldman JW; Adil I. Daud, Michelle T. Ashworth, Alan P. Venook, Jennifer A. Grabowsky, and Pamela N. Munster, University of California, San Francisco, San Francisco; Jonathan W. Goldman and Lee S. Rosen, University of California, Los Angeles, Santa Monica, CA; Jonathan Strosberg and Gregory Springett, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; David Mendelson, Pinnacle Oncology Hematology, Scottsdale, AZ; and Sabine Loechner, Frances Shanahan, David Parry, Stuart Shumway, Tomoko Freshwater, Christopher Sorge, Soonmo Peter Kang, and Randi Isaacs, Merck, Whitehouse Station, NJ., Mendelson D; Adil I. Daud, Michelle T. Ashworth, Alan P. Venook, Jennifer A. Grabowsky, and Pamela N. Munster, University of California, San Francisco, San Francisco; Jonathan W. Goldman and Lee S. Rosen, University of California, Los Angeles, Santa Monica, CA; Jonathan Strosberg and Gregory Springett, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; David Mendelson, Pinnacle Oncology Hematology, Scottsdale, AZ; and Sabine Loechner, Frances Shanahan, David Parry, Stuart Shumway, Tomoko Freshwater, Christopher Sorge, Soonmo Peter Kang, and Randi Isaacs, Merck, Whitehouse Station, NJ., Springett G; Adil I. Daud, Michelle T. Ashworth, Alan P. Venook, Jennifer A. Grabowsky, and Pamela N. Munster, University of California, San Francisco, San Francisco; Jonathan W. Goldman and Lee S. Rosen, University of California, Los Angeles, Santa Monica, CA; Jonathan Strosberg and Gregory Springett, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; David Mendelson, Pinnacle Oncology Hematology, Scottsdale, AZ; and Sabine Loechner, Frances Shanahan, David Parry, Stuart Shumway, Tomoko Freshwater, Christopher Sorge, Soonmo Peter Kang, and Randi Isaacs, Merck, Whitehouse Station, NJ., Venook AP; Adil I. Daud, Michelle T. Ashworth, Alan P. Venook, Jennifer A. Grabowsky, and Pamela N. Munster, University of California, San Francisco, San Francisco; Jonathan W. Goldman and Lee S. Rosen, University of California, Los Angeles, Santa Monica, CA; Jonathan Strosberg and Gregory Springett, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; David Mendelson, Pinnacle Oncology Hematology, Scottsdale, AZ; and Sabine Loechner, Frances Shanahan, David Parry, Stuart Shumway, Tomoko Freshwater, Christopher Sorge, Soonmo Peter Kang, and Randi Isaacs, Merck, Whitehouse Station, NJ., Loechner S; Adil I. Daud, Michelle T. Ashworth, Alan P. Venook, Jennifer A. Grabowsky, and Pamela N. Munster, University of California, San Francisco, San Francisco; Jonathan W. Goldman and Lee S. Rosen, University of California, Los Angeles, Santa Monica, CA; Jonathan Strosberg and Gregory Springett, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; David Mendelson, Pinnacle Oncology Hematology, Scottsdale, AZ; and Sabine Loechner, Frances Shanahan, David Parry, Stuart Shumway, Tomoko Freshwater, Christopher Sorge, Soonmo Peter Kang, and Randi Isaacs, Merck, Whitehouse Station, NJ., Rosen LS; Adil I. Daud, Michelle T. Ashworth, Alan P. Venook, Jennifer A. Grabowsky, and Pamela N. Munster, University of California, San Francisco, San Francisco; Jonathan W. Goldman and Lee S. Rosen, University of California, Los Angeles, Santa Monica, CA; Jonathan Strosberg and Gregory Springett, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; David Mendelson, Pinnacle Oncology Hematology, Scottsdale, AZ; and Sabine Loechner, Frances Shanahan, David Parry, Stuart Shumway, Tomoko Freshwater, Christopher Sorge, Soonmo Peter Kang, and Randi Isaacs, Merck, Whitehouse Station, NJ., Shanahan F; Adil I. Daud, Michelle T. Ashworth, Alan P. Venook, Jennifer A. Grabowsky, and Pamela N. Munster, University of California, San Francisco, San Francisco; Jonathan W. Goldman and Lee S. Rosen, University of California, Los Angeles, Santa Monica, CA; Jonathan Strosberg and Gregory Springett, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; David Mendelson, Pinnacle Oncology Hematology, Scottsdale, AZ; and Sabine Loechner, Frances Shanahan, David Parry, Stuart Shumway, Tomoko Freshwater, Christopher Sorge, Soonmo Peter Kang, and Randi Isaacs, Merck, Whitehouse Station, NJ., Parry D; Adil I. Daud, Michelle T. Ashworth, Alan P. Venook, Jennifer A. Grabowsky, and Pamela N. Munster, University of California, San Francisco, San Francisco; Jonathan W. Goldman and Lee S. Rosen, University of California, Los Angeles, Santa Monica, CA; Jonathan Strosberg and Gregory Springett, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; David Mendelson, Pinnacle Oncology Hematology, Scottsdale, AZ; and Sabine Loechner, Frances Shanahan, David Parry, Stuart Shumway, Tomoko Freshwater, Christopher Sorge, Soonmo Peter Kang, and Randi Isaacs, Merck, Whitehouse Station, NJ., Shumway S; Adil I. Daud, Michelle T. Ashworth, Alan P. Venook, Jennifer A. Grabowsky, and Pamela N. Munster, University of California, San Francisco, San Francisco; Jonathan W. Goldman and Lee S. Rosen, University of California, Los Angeles, Santa Monica, CA; Jonathan Strosberg and Gregory Springett, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; David Mendelson, Pinnacle Oncology Hematology, Scottsdale, AZ; and Sabine Loechner, Frances Shanahan, David Parry, Stuart Shumway, Tomoko Freshwater, Christopher Sorge, Soonmo Peter Kang, and Randi Isaacs, Merck, Whitehouse Station, NJ., Grabowsky JA; Adil I. Daud, Michelle T. Ashworth, Alan P. Venook, Jennifer A. Grabowsky, and Pamela N. Munster, University of California, San Francisco, San Francisco; Jonathan W. Goldman and Lee S. Rosen, University of California, Los Angeles, Santa Monica, CA; Jonathan Strosberg and Gregory Springett, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; David Mendelson, Pinnacle Oncology Hematology, Scottsdale, AZ; and Sabine Loechner, Frances Shanahan, David Parry, Stuart Shumway, Tomoko Freshwater, Christopher Sorge, Soonmo Peter Kang, and Randi Isaacs, Merck, Whitehouse Station, NJ., Freshwater T; Adil I. Daud, Michelle T. Ashworth, Alan P. Venook, Jennifer A. Grabowsky, and Pamela N. Munster, University of California, San Francisco, San Francisco; Jonathan W. Goldman and Lee S. Rosen, University of California, Los Angeles, Santa Monica, CA; Jonathan Strosberg and Gregory Springett, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; David Mendelson, Pinnacle Oncology Hematology, Scottsdale, AZ; and Sabine Loechner, Frances Shanahan, David Parry, Stuart Shumway, Tomoko Freshwater, Christopher Sorge, Soonmo Peter Kang, and Randi Isaacs, Merck, Whitehouse Station, NJ., Sorge C; Adil I. Daud, Michelle T. Ashworth, Alan P. Venook, Jennifer A. Grabowsky, and Pamela N. Munster, University of California, San Francisco, San Francisco; Jonathan W. Goldman and Lee S. Rosen, University of California, Los Angeles, Santa Monica, CA; Jonathan Strosberg and Gregory Springett, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; David Mendelson, Pinnacle Oncology Hematology, Scottsdale, AZ; and Sabine Loechner, Frances Shanahan, David Parry, Stuart Shumway, Tomoko Freshwater, Christopher Sorge, Soonmo Peter Kang, and Randi Isaacs, Merck, Whitehouse Station, NJ., Kang SP; Adil I. Daud, Michelle T. Ashworth, Alan P. Venook, Jennifer A. Grabowsky, and Pamela N. Munster, University of California, San Francisco, San Francisco; Jonathan W. Goldman and Lee S. Rosen, University of California, Los Angeles, Santa Monica, CA; Jonathan Strosberg and Gregory Springett, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; David Mendelson, Pinnacle Oncology Hematology, Scottsdale, AZ; and Sabine Loechner, Frances Shanahan, David Parry, Stuart Shumway, Tomoko Freshwater, Christopher Sorge, Soonmo Peter Kang, and Randi Isaacs, Merck, Whitehouse Station, NJ., Isaacs R; Adil I. Daud, Michelle T. Ashworth, Alan P. Venook, Jennifer A. Grabowsky, and Pamela N. Munster, University of California, San Francisco, San Francisco; Jonathan W. Goldman and Lee S. Rosen, University of California, Los Angeles, Santa Monica, CA; Jonathan Strosberg and Gregory Springett, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; David Mendelson, Pinnacle Oncology Hematology, Scottsdale, AZ; and Sabine Loechner, Frances Shanahan, David Parry, Stuart Shumway, Tomoko Freshwater, Christopher Sorge, Soonmo Peter Kang, and Randi Isaacs, Merck, Whitehouse Station, NJ., Munster PN; Adil I. Daud, Michelle T. Ashworth, Alan P. Venook, Jennifer A. Grabowsky, and Pamela N. Munster, University of California, San Francisco, San Francisco; Jonathan W. Goldman and Lee S. Rosen, University of California, Los Angeles, Santa Monica, CA; Jonathan Strosberg and Gregory Springett, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; David Mendelson, Pinnacle Oncology Hematology, Scottsdale, AZ; and Sabine Loechner, Frances Shanahan, David Parry, Stuart Shumway, Tomoko Freshwater, Christopher Sorge, Soonmo Peter Kang, and Randi Isaacs, Merck, Whitehouse Station, NJ.
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2015 Mar 20; Vol. 33 (9), pp. 1060-6. Date of Electronic Publication: 2015 Jan 20.
Autor:
Kelley RK; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco (UCSF), San Francisco. Electronic address: katie.kelley@ucsf.edu., Nimeiri HS; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago., Munster PN; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco (UCSF), San Francisco., Vergo MT; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago., Huang Y; Drug Studies Unit, Department of Bioengineering & Therapeutic Sciences., Li CM; Drug Studies Unit, Department of Bioengineering & Therapeutic Sciences., Hwang J; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco (UCSF), San Francisco., Mulcahy MF; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago., Yeh BM; Department of Radiology, UCSF, San Francisco., Kuhn P; Department of Cell Biology, The Scripps Research Institute, La Jolla, USA., Luttgen MS; Department of Cell Biology, The Scripps Research Institute, La Jolla, USA., Grabowsky JA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco (UCSF), San Francisco., Stucky-Marshall L; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago., Korn WM; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco (UCSF), San Francisco., Ko AH; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco (UCSF), San Francisco., Bergsland EK; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco (UCSF), San Francisco., Benson AB 3rd; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago., Venook AP; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco (UCSF), San Francisco.
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2013 Jul; Vol. 24 (7), pp. 1900-1907. Date of Electronic Publication: 2013 Mar 21.
Autor:
Grabowsky JA; Early Phase Investigational Therapeutics, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, USA. Jennifer.Grabowsky@ucsfmedctr.org
Publikováno v:
The Annals of pharmacotherapy [Ann Pharmacother] 2013 Jul-Aug; Vol. 47 (7-8), pp. 1055-63. Date of Electronic Publication: 2013 Jun 11.