Synthesis and biological evaluation of vioprolide B and its dehydrobutyrine-glycine analogue.

Autor: Osorio Reineke N; Technische Universität München, School of Natural Sciences, Department of Chemistry and Catalysis Research Center, Lichtenbergstraße 4, 85747 Garching, Germany. thorsten.bach@ch.tum.de., Elsen FAV; Technische Universität München, School of Natural Sciences, Department of Bioscience and Center for Functional Protein Assemblies, Ernst-Otto-Fischer-Straße 8, 85747 Garching, Germany., Grab HA; Technische Universität München, School of Natural Sciences, Department of Chemistry and Catalysis Research Center, Lichtenbergstraße 4, 85747 Garching, Germany. thorsten.bach@ch.tum.de., Mostert D; Technische Universität München, School of Natural Sciences, Department of Bioscience and Center for Functional Protein Assemblies, Ernst-Otto-Fischer-Straße 8, 85747 Garching, Germany., Sieber SA; Technische Universität München, School of Natural Sciences, Department of Bioscience and Center for Functional Protein Assemblies, Ernst-Otto-Fischer-Straße 8, 85747 Garching, Germany., Bach T; Technische Universität München, School of Natural Sciences, Department of Chemistry and Catalysis Research Center, Lichtenbergstraße 4, 85747 Garching, Germany. thorsten.bach@ch.tum.de.

Publikováno v: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2024 Aug 01; Vol. 60 (63), pp. 8272-8275. Date of Electronic Publication: 2024 Aug 01.

Biosynthesis and Heterologous Production of Vioprolides: Rational Biosynthetic Engineering and Unprecedented 4-Methylazetidinecarboxylic Acid Formation.

Autor: Yan F; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Center for Infection Research, and Department of Pharmacy, Saarland University, Campus Building E8.1, 66123, Saarbrücken, Germany., Auerbach D; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Center for Infection Research, and Department of Pharmacy, Saarland University, Campus Building E8.1, 66123, Saarbrücken, Germany., Chai Y; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Center for Infection Research, and Department of Pharmacy, Saarland University, Campus Building E8.1, 66123, Saarbrücken, Germany., Keller L; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Center for Infection Research, and Department of Pharmacy, Saarland University, Campus Building E8.1, 66123, Saarbrücken, Germany., Tu Q; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Center for Infection Research, and Department of Pharmacy, Saarland University, Campus Building E8.1, 66123, Saarbrücken, Germany., Hüttel S; Helmholtz Centre for Infection Research, Department of Microbial Drugs, Braunschweig, Germany., Glemser A; Helmholtz Centre for Infection Research, Department of Microbial Drugs, Braunschweig, Germany., Grab HA; Lehrstuhl für Organische Chemie I, Technische Universität München, Lichtenbergstrasse 4, 85747, Garching, Germany., Bach T; Lehrstuhl für Organische Chemie I, Technische Universität München, Lichtenbergstrasse 4, 85747, Garching, Germany., Zhang Y; Shandong University-Helmholtz Joint Institute of Biotechnology, State Key Laboratory of Microbial Technology, School of Life Science, Shandong University, Qingdao, P. R. China., Müller R; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Center for Infection Research, and Department of Pharmacy, Saarland University, Campus Building E8.1, 66123, Saarbrücken, Germany.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2018 Jul 09; Vol. 57 (28), pp. 8754-8759. Date of Electronic Publication: 2018 Jun 08.