Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Grażyna E. Sroga"'
Publikováno v:
JBMR Plus, Vol 6, Iss 2, Pp n/a-n/a (2022)
ABSTRACT Obesity is a common comorbidity of type 2 diabetes (T2D). Therefore, increased risk of fragility fractures in T2D is often confounded by the effects of obesity. This study was conducted to elucidate the mechanistic basis by which T2D alone l
Externí odkaz:
https://doaj.org/article/aa580991c5e04f2a93fd918fa6e64e39
Autor:
Grażyna E. Sroga, Deepak Vashishth
Publikováno v:
JBMR Plus, Vol 5, Iss 11, Pp n/a-n/a (2021)
ABSTRACT It has been a challenge to establish a link between specific advanced glycation end products (AGEs) as causal agents of different pathologies and age‐related diseases, primarily because of the lack of suitable in vitro experimental strateg
Externí odkaz:
https://doaj.org/article/d08c99eedae841db8cb94346a00ca5cc
Publikováno v:
Current Opinion in Endocrinology, Diabetes & Obesity. 29:333-342
Multiple biochemical and biophysical approaches have been broadly used for detection and quantitation of posttranslational protein modifications associated with diabetic bone, yet these techniques present a variety of challenges. In this review, we d
Publikováno v:
JBMR Plus. 6
Obesity is a common comorbidity of type 2 diabetes (T2D). Therefore, increased risk of fragility fractures in T2D is often confounded by the effects of obesity. This study was conducted to elucidate the mechanistic basis by which T2D alone leads to s
Autor:
Deepak Vashishth, Grażyna E. Sroga
Publikováno v:
JBMR Plus, Vol 5, Iss 11, Pp n/a-n/a (2021)
JBMR Plus
JBMR Plus
It has been a challenge to establish a link between specific advanced glycation end products (AGEs) as causal agents of different pathologies and age‐related diseases, primarily because of the lack of suitable in vitro experimental strategies facil
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117240 (2015)
To better understand some aspects of bone matrix glycation, we used an in vitro glycation approach. Within two weeks, our glycation procedures led to the formation of advanced glycation end products (AGEs) at the levels that corresponded to approx. 2
Externí odkaz:
https://doaj.org/article/1aa5ebe7e1044ada82c4593c0226e0bc
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0117046 (2015)
Despite our extensive knowledge of insulin-like growth factor 1 (IGF1) action on the growing skeleton, its role in skeletal homeostasis during aging and age-related development of certain diseases is still unclear. Advanced glycation end products (AG
Externí odkaz:
https://doaj.org/article/4aea37fc72db46e2b2c0d50c81e19a32
Publikováno v:
FASEB J
Biological functions, including glycemic control and bone metabolism, are highly influenced by the body's internal clock. Circadian rhythms are biological rhythms that run with a period close to 24 hours and receive input from environmental stimuli,