Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Grażyna Chwatko"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Cysteine and glutathione can be applied as therapeutic targets in civilization diseases such as diabetes mellitus and cancers. On the other hand, an elevated concentration of homocysteine, and its metabolites such as homocysteine thiolactone
Externí odkaz:
https://doaj.org/article/dd839015bdd74480be3d91d5f536f5f7
Autor:
Justyna Piechocka, Natalia Matwiej, Marta Gaweł, Michał Matyjaszczyk, Rafał Głowacki, Grażyna Chwatko
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract The report presents robust and high throughput methods, based on liquid chromatography coupled with evaporative light scattering detection (HPLC-ELSD), for the simultaneous determination of major metabolites of ibuprofen (IBU), namely 2-hydr
Externí odkaz:
https://doaj.org/article/0a59940182224a0c9c9dbb869c0e5443
Autor:
Katarzyna Kurpet, Grażyna Chwatko
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The aim of this study was to develop and validate a simple, fast, and universal reversed-phase high-performance liquid chromatography method with fluorescence detection for the quantitation and evaluation of the stability of bakuchiol in cos
Externí odkaz:
https://doaj.org/article/a9e60402e7fb415dbfb657cc5f8fc6c7
Autor:
Grażyna Chwatko, Marta Krawczyk, Małgorzata Iciek, Adrianna Kamińska, Anna Bilska-Wilkosz, Bernadeta Marcykiewicz, Rafał Głowacki
Publikováno v:
Arabian Journal of Chemistry, Vol 12, Iss 8, Pp 4878-4886 (2019)
This paper describes the development and validation of an HPLC method for the determination of protein bound and total lipoic acid in human plasma. The essential steps in the total lipoic acid assay include reduction of disulfide bridge with tris(2-c
Externí odkaz:
https://doaj.org/article/202c6edf235b4a96bc94e560d0452633
Autor:
Katarzyna Kurpet, Grażyna Chwatko
Publikováno v:
Molecules, Vol 27, Iss 19, p 6640 (2022)
Psoriasis is one of the most common inflammatory skin diseases affecting about 1–3% of the population. One of the characteristic abnormalities in psoriasis is the excessive production of antimicrobial peptides and proteins, which play an essential
Externí odkaz:
https://doaj.org/article/e42ef3d140a74e8b95bcc9e1de1e9ca5
Publikováno v:
Molecules, Vol 26, Iss 11, p 3321 (2021)
Biothiols are extremely powerful antioxidants that protect cells against the effects of oxidative stress. They are also considered relevant disease biomarkers, specifically risk factors for cardiovascular disease. In this paper, a new procedure for t
Externí odkaz:
https://doaj.org/article/3cdf797269204b8fa0ba50991ae496a4
Autor:
Patrycja Olejarz, Grażyna Chwatko, Paweł Kubalczyk, Krystian Purgat, Rafał Głowacki, Kamila Borowczyk
Publikováno v:
Pharmaceuticals, Vol 13, Iss 11, p 367 (2020)
Tenofovir disoproxil fumarate is widely used in the therapy of human immunodeficiency virus and hepatitis B virus; however, a high concentration of the prodrug effects kidney function damage. To control the effectiveness of kidney functions in treate
Externí odkaz:
https://doaj.org/article/fb931bf4537b47aeba01f8629163c5ec
Autor:
Magdalena Górny, Anna Bilska-Wilkosz, Małgorzata Iciek, Marta Hereta, Kinga Kamińska, Adrianna Kamińska, Grażyna Chwatko, Zofia Rogóż, Elżbieta Lorenc-Koci
Publikováno v:
Antioxidants, Vol 9, Iss 6, p 538 (2020)
The aim of the present study was to assess the effects of l-buthionine-(S,R)-sulfoximine (BSO), a glutathione (GSH) synthesis inhibitor, and GBR 12909, a dopamine reuptake inhibitor, administered alone or in combination to Sprague-Dawley rats during
Externí odkaz:
https://doaj.org/article/ec15f9e84106426b8d629183ffeb05a5
Autor:
Magdalena Górny, Agnieszka Wnuk, Adrianna Kamińska, Kinga Kamińska, Grażyna Chwatko, Anna Bilska-Wilkosz, Małgorzata Iciek, Małgorzata Kajta, Zofia Rogóż, Elżbieta Lorenc-Koci
Publikováno v:
Molecules, Vol 24, Iss 23, p 4253 (2019)
Impaired glutathione (GSH) synthesis and dopaminergic transmission are important factors in the pathophysiology of schizophrenia. Our research aimed to assess the effects of l-buthionine-(S,R)-sulfoximine (BSO), a GSH synthesis inhibitor, and GBR 129
Externí odkaz:
https://doaj.org/article/11478aaae0f0430cab0b0cdb6dff8941
Publikováno v:
The European Zoological Journal, Vol 88, Iss 1, Pp 328-339 (2021)
The fecundity and sexual structure of weatherfish (Misgurnus fossilis) population, an inperilled and protected freshwater fish with a poorly known life history, was studied in three waterbodies: the River Ner, the Południowy canal and the Nowy Rów