Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Graçiela Pineyro"'
Autor:
Besma Benredjem, Graciela Pineyro
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Cannabis extracts are being increasingly used to mitigate chronic pain. Current guidelines for their prescription rely on Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) content as well as the ratio of these major cannabinoids pres
Externí odkaz:
https://doaj.org/article/d6b3de9fe90f448ab8da756daf6074a8
Autor:
Besma Benredjem, Jonathan Gallion, Dennis Pelletier, Paul Dallaire, Johanie Charbonneau, Darren Cawkill, Karim Nagi, Mark Gosink, Viktoryia Lukasheva, Stephen Jenkinson, Yong Ren, Christopher Somps, Brigitte Murat, Emma Van Der Westhuizen, Christian Le Gouill, Olivier Lichtarge, Anne Schmidt, Michel Bouvier, Graciela Pineyro
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Identifying ligands which activate the specific effectors driving particular in vivo drug effects remains challenging. Here, the authors apply unsupervised clustering of pharmacodynamic parameters to classify GPCR ligands into different categories wi
Externí odkaz:
https://doaj.org/article/c0db3f1cf110426bbd5f35d40fd3681b
Autor:
Besma Benredjem, Jonathan Gallion, Dennis Pelletier, Paul Dallaire, Johanie Charbonneau, Darren Cawkill, Karim Nagi, Mark Gosink, Viktoryia Lukasheva, Stephen Jenkinson, Yong Ren, Christopher Somps, Brigitte Murat, Emma Van Der Westhuizen, Christian Le Gouill, Olivier Lichtarge, Anne Schmidt, Michel Bouvier, Graciela Pineyro
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/1f09235de66f4fc295108bc582f6d396
Autor:
Guillaume Lucas, Jenny Du, Thomas Romeas, Ouissame Mnie-Filali, Nasser Haddjeri, Graciela Piñeyro, Guy Debonnel
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9253 (2010)
We have recently reported that serotonin(4) (5-HT(4)) receptor agonists have a promising potential as fast-acting antidepressants. Here, we assess the extent to which this property may be optimized by the concomitant use of conventional antidepressan
Externí odkaz:
https://doaj.org/article/b32b363271aa408f8d9e62364c947852
Autor:
Marisol Lavertu-Jolin, Bidisha Chattopadhyaya, Pegah Chehrazi, Denise Carrier, Florian Wünnemann, Séverine Leclerc, Félix Dumouchel, Derek Robertson, Hicham Affia, Kamal Saba, Vijaya Gopal, Anant Bahadur Patel, Gregor Andelfinger, Graçiela Pineyro, Graziella Di Cristo
Publikováno v:
Molecular Psychiatry.
While persistence of fear memories is essential for survival, a failure to inhibit fear in response to harmless stimuli is a feature of anxiety disorders. Extinction training only temporarily suppresses fear memory recovery in adults, but it is highl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b0479ea456c539bb78776ba451f634a
https://doi.org/10.1038/s41380-023-02085-0
https://doi.org/10.1038/s41380-023-02085-0
Autor:
Marisol Lavertu-Jolin, Bidisha Chattopadhyaya, Pegah Chehrazi, Denise Carrier, Florian Wünnemann, Séverine Leclerc, Félix Dumouchel, Derek Robertson, Hicham Affia, Kamal Saba, Vijaya Gopal, Anant Bahadur Patel, Gregor Andelfinger, Graçiela Pineyro, Graziella Di Cristo
Failure of inhibiting fear in response to harmless stimuli contributes to anxiety disorders. Extinction training only temporarily suppresses fear memories in adults, but it is highly effective in juveniles. GABAergic parvalbumin-positive (PV+) cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34a79bcbc547cbb2b187d20f42777e22
https://doi.org/10.1101/2022.08.09.503382
https://doi.org/10.1101/2022.08.09.503382
