Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Graça Lobo"'
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
Background The measures implemented by governments worldwide to control and prevent the spread of the COVID-19 have impacted the populations and directly influenced individuals’ quality of life and consumption habits. Objective This work investigat
Externí odkaz:
https://doaj.org/article/04edf54b6d61451cb0f16a9f6ec94960
Autor:
Bárbara Guerra Leal, Aurora Barros-Barbosa, Fátima Ferreirinha, João Chaves, Rui Rangel, Agostinho Santos, Cláudia Carvalho, Ricardo Martins-Ferreira, Raquel Samões, Joel Freitas, João Lopes, João Ramalheira, Maria Graça Lobo, António Martins da Silva, Paulo P. Costa, Paulo Correia-de-Sá
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Objective: ATP-gated ionotropic P2X7 receptors (P2X7R) actively participate in epilepsy and other neurological disorders. Neocortical nerve terminals of patients with Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis (MTLE-HS) express higher P
Externí odkaz:
https://doaj.org/article/1edfa87c130f455db19fd31818e2efb9
Relation of COVID-19 with liver diseases and their impact on healthcare systems: The Portuguese case
Publikováno v:
World Journal of Gastroenterology. 29:1109-1122
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Corticosteroids exert a dual role in eukaryotic cells through their action via (1) intracellular receptors (slow genomic responses), or (2) membrane-bound receptors (fast non-genomic responses). Highly vulnerable regions of the brain, like the hippoc
Externí odkaz:
https://doaj.org/article/57e2517e50744428bc9f642105c85141
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0260322 (2021)
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE
Background The measures implemented by governments worldwide to control and prevent the spread of the COVID-19 have impacted the populations and directly influenced individuals’ quality of life and consumption habits. Objective This work investigat
Autor:
Aurora Barros-Barbosa, Paulo Correia-de-Sá, J. Miguel Cordeiro, M. Graça Lobo, Ângela Oliveira
Publikováno v:
Neurochemistry International. 112:81-95
γ-Aminobutyric acid (GABA) and glutamate (Glu) are the main inhibitory and excitatory neurotransmitters in the central nervous system (CNS), respectively. Fine tuning regulation of extracellular levels of these amino acids is essential for normal br
Akademický článek
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Autor:
Fátima Ferreirinha, M. Graça Lobo, Paulo Correia-de-Sá, Marina Mendes, Jean Sévigny, Ângela Oliveira, Julie Pelletier, J. Miguel Cordeiro, Rui Rangel, Agostinho Santos, Aurora Barros-Barbosa
Refractoriness to existing medications of up to 80 % of the patients with mesial temporal lobe epilepsy (MTLE) prompts for finding new antiepileptic drug targets. The adenosine A2A receptor emerges as an interesting pharmacological target since its e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff198f045815514e5c9ce27e604b7c6
https://europepmc.org/articles/PMC5124012/
https://europepmc.org/articles/PMC5124012/
Autor:
Rui Rangel, Agostinho Santos, J. Miguel Cordeiro, Fátima Ferreirinha, Sónia Guerra-Gomes, Aurora Barros-Barbosa, Ana L. Fonseca, M. Graça Lobo, Paulo Correia-de-Sá
Publikováno v:
Epilepsia. 57(1)
Summary Objective Thirty percent of patients with epilepsy are refractory to medication. The majority of these patients have mesial temporal lobe epilepsy (MTLE). This prompts for new pharmacologic targets, like ATP-mediated signaling pathways, since
Akademický článek
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