Biomarkers for hypertrophic chondrocyte differentiation are associated with spatial cellular organisation and suggest endochondral ossification-like processes in osteoarthritic cartilage: An exploratory study.

Autor: Wolfgart JM; Laboratory of Cell Biology, Department of Orthopaedic Surgery University Hospital of Tübingen, Waldhörnlestraße 22, D-72072, Tübingen, Germany.; Department of Orthopaedic, Trauma, and Reconstructive Surgery, Division of Arthroplasty, RWTH Aachen University Hospital, Pauwelsstraße 30, D-52074, Aachen, Germany., Grötzner LC; Laboratory of Cell Biology, Department of Orthopaedic Surgery University Hospital of Tübingen, Waldhörnlestraße 22, D-72072, Tübingen, Germany.; Medical Faculty of the University of Tübingen, D-72076, Tübingen, Germany., Hemayatkar-Fink S; Laboratory of Cell Biology, Department of Orthopaedic Surgery University Hospital of Tübingen, Waldhörnlestraße 22, D-72072, Tübingen, Germany.; Department of Trauma and Orthopaedic Surgery and Sports Medicine, Kreiskliniken Reutlingen, Steinenbergstraße 31, D-72764, Reutlingen, Germany., Schwitalle M; Winghofer Medicum, Röntgenstraße 38, D-72108, Rottenburg am Neckar, Germany., Bonnaire FC; Laboratory of Cell Biology, Department of Orthopaedic Surgery University Hospital of Tübingen, Waldhörnlestraße 22, D-72072, Tübingen, Germany.; Institute for Diagnostic and Interventional Radiology, Kreiskliniken Reutlingen, Steinenbergstraße 31, D-72764, Reutlingen, Germany., Feierabend M; Laboratory of Cell Biology, Department of Orthopaedic Surgery University Hospital of Tübingen, Waldhörnlestraße 22, D-72072, Tübingen, Germany.; Metabolic Reconstruction and Flux Modelling, Institue for Plant Sciences, University of Cologne, Germany., Danalache M; Laboratory of Cell Biology, Department of Orthopaedic Surgery University Hospital of Tübingen, Waldhörnlestraße 22, D-72072, Tübingen, Germany., Hofmann UK; Laboratory of Cell Biology, Department of Orthopaedic Surgery University Hospital of Tübingen, Waldhörnlestraße 22, D-72072, Tübingen, Germany.; Department of Orthopaedic, Trauma, and Reconstructive Surgery, Division of Arthroplasty, RWTH Aachen University Hospital, Pauwelsstraße 30, D-52074, Aachen, Germany.

Publikováno v: Journal of orthopaedic translation [J Orthop Translat] 2024 Sep 13; Vol. 48, pp. 232-243. Date of Electronic Publication: 2024 Sep 13 (Print Publication: 2024).