Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Grégory Scherrer"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract The neural substrate of pain experience has been described as a dense network of connected brain regions. However, the connectivity pattern of these brain regions remains elusive, precluding a deeper understanding of how pain emerges from th
Externí odkaz:
https://doaj.org/article/d1104b420e5f470e9728102c2d70fe79
Autor:
Rita R. Fagan, David F. Lee, Matan Geron, Grégory Scherrer, Mark von Zastrow, Aliza T. Ehrlich
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114164- (2024)
Summary: Opioid receptors are therapeutically important G protein-coupled receptors (GPCRs) with diverse neuromodulatory effects. The functional consequences of opioid receptor activation are known to depend on receptor location in the plasma membran
Externí odkaz:
https://doaj.org/article/bc53921370f5478ea5e16804e7e64541
Autor:
Amelia J. Christensen, Shrivats M. Iyer, Amaury François, Saurabh Vyas, Charu Ramakrishnan, Sam Vesuna, Karl Deisseroth, Grégory Scherrer, Scott L. Delp
Publikováno v:
Cell Reports, Vol 17, Iss 6, Pp 1699-1710 (2016)
Spinal dorsal horn circuits receive, process, and transmit somatosensory information. To understand how specific components of these circuits contribute to behavior, it is critical to be able to directly modulate their activity in unanesthetized in v
Externí odkaz:
https://doaj.org/article/e897a05e89ac4a5d94efcdeb77716b10
Publikováno v:
eLife, Vol 8 (2019)
The medial thalamus (MThal), anterior cingulate cortex (ACC) and striatum play important roles in affective-motivational pain processing and reward learning. Opioids affect both pain and reward through uncharacterized modulation of this circuitry. Th
Externí odkaz:
https://doaj.org/article/ac340174c74f4ca198676c590356d29a
Autor:
Yu-Wei Wu, Jae-Ick Kim, Vivianne L. Tawfik, Rupa R. Lalchandani, Grégory Scherrer, Jun B. Ding
Publikováno v:
Cell Reports, Vol 10, Iss 1, Pp 75-87 (2015)
Changes in basal ganglia plasticity at the corticostriatal and thalamostriatal levels are required for motor learning. Endocannabinoid-dependent long-term depression (eCB-LTD) is known to be a dominant form of synaptic plasticity expressed at these g
Externí odkaz:
https://doaj.org/article/98dd285cb55541c58e3947972235f8a8
Autor:
Amynah A A Pradhan, Jérôme A J Becker, Grégory Scherrer, Petra Tryoen-Toth, Dominique Filliol, Audrey Matifas, Dominique Massotte, Claire Gavériaux-Ruff, Brigitte L Kieffer
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5425 (2009)
GPCRs regulate a remarkable diversity of biological functions, and are thus often targeted for drug therapies. Stimulation of a GPCR by an extracellular ligand triggers receptor signaling via G proteins, and this process is highly regulated. Receptor
Externí odkaz:
https://doaj.org/article/926e75bd50c5406895c1b895f56a9c6a
Autor:
Maria Zamfir, Behrang Sharif, Samantha Locke, Aliza T. Ehrlich, Nicole E. Ochandarena, Grégory Scherrer, Alfredo Ribeiro-da-Silva, Brigitte L. Kieffer, Philippe Séguéla
Publikováno v:
Pain. 164:703-716
The anterior cingulate cortex (ACC) processes the affective component of pain, whereas the primary somatosensory cortex (S1) is involved in its sensory-discriminative component. Injection of morphine in the ACC has been reported to be analgesic, and
Autor:
Nicholas F. Hug, Nicole Mercer Lindsay, William M. McCallum, Justin Bryan, Karen Huang, Nicole Ochandarena, Adrien Tassou, Grégory Scherrer
Opioids produce profound and diverse effects on a range of behaviors, many driven by brainstem activity; however, the presence of opioid and opioid-like receptors at this level has been poorly studied outside of nociceptive structures and components
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27e1fb25e39ee8392b940b3354664f13
https://doi.org/10.1101/2022.12.24.521865
https://doi.org/10.1101/2022.12.24.521865
Autor:
Adrien Tassou, Karen Huang, Valentina Morales, Jonathan Saju, Sy'Keria Garrison, Grégory Scherrer
Publikováno v:
The Journal of Pain. 24:19-20