Semaglutide treatment attenuates vessel remodelling in ApoE−/− mice following vascular injury and blood flow perturbation

Autor: Ditte Marie Jensen, Gry Freja Skovsted, Mathilde Frederikke Bjørn Bonde, Jacob Fog Bentzon, Bidda Rolin, Grégory Franck, Maria Katarina Elm Ougaard, Louise Marie Voetmann, Julian Christoffer Bachmann, Anna Uryga, Charles Pyke, Rikke Kaae Kirk, Henning Hvid, Lotte Bjerre Knudsen, Jens Lykkesfeldt, Michael Nyberg

Publikováno v: Atherosclerosis Plus, Vol 49, Iss , Pp 32-41 (2022)

Background and aims: Randomized clinical studies have shown a reduction in cardiovascular outcomes with glucagon-like peptide 1 receptor agonist (GLP-1RA) treatment with the hypothesized mechanisms being an underlying effect on atherosclerosis. Here,

Externí odkaz: https://doaj.org/article/f47cfbc975fb429383e07990f4efcd05

Role of mechanical stress and neutrophils in the pathogenesis of plaque erosion

Autor: Grégory Franck

Publikováno v: In Atherosclerosis February 2021 318:60-69

Opposing Strain Directions on Adjacent Left Ventricular Segments Predict Fibrotic Remodeling after Acute Myocardial Infarction

Autor: Tania Dubois-Mignon, Varouna Syvannarath, Marylou Para, Sylvain Richard, Pierre Sicard, Antonino Nicoletti, Giuseppina Caligiuri, Grégory Franck

BackgroundDespite similar levels of coronary occlusion and standard of care management, the occurrence of scarring over adaptive heart repair following acute myocardial infarction (AMI) remains unpredictable. Recent studies indicate that mechanical c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f025dd5ebf6bba4e18cf244942b42e1
https://doi.org/10.1101/2023.03.20.533539

Relationship of Iron Deposition to Calcium Deposition in Human Aortic Valve Leaflets

Autor: Grégory Franck, Dimitri Arangalage, Marie-Paule Jacob-Lenet, Jean-Baptiste Michel, Christine Choqueux, Giuseppina Caligiuri, Catherine Deschildre, Antonino Nicoletti, Marion Morvan, Fanny Perez, David Messika-Zeitoun, Léa Cattan-Levy, Guillaume Even, Jamila Laschet, Magnus Bäck, Isabelle Codogno

Publikováno v: Journal of the American College of Cardiology
Journal of the American College of Cardiology, Elsevier, 2019, 73, pp.1043-1054. ⟨10.1016/j.jacc.2018.12.042⟩

Background Intraleaflet hematomas are associated with advanced stages of aortic valve calcification and suspected to be involved in disease progression. However, the mechanism by which the entry of blood cells into the valves affects the biology of a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd3750be4a68a6667a9bf2d3a2e4b95
https://doi.org/10.1016/j.jacc.2018.12.042

Synthesis of cationic quaternized pullulan derivatives for miRNA delivery

Autor: Paola Aprile, Grégory Franck, Cédric Chauvierre, Didier Letourneur, Laura Marcela Forero Ramirez, Frédéric Chaubet, Fernanda C. Moraes, Joana C. Antunes

Publikováno v: International Journal of Pharmaceutics
International Journal of Pharmaceutics, Elsevier, 2020, 577, pp.119041. ⟨10.1016/j.ijpharm.2020.119041⟩
International Journal of Pharmaceutics, 2020, 577, pp.119041. ⟨10.1016/j.ijpharm.2020.119041⟩

International audience; Pullulan is a natural polysaccharide of potential interest for biomedical applications due to its non-toxic, non-immunogenic and biodegradable properties. The aim of this work was to synthesize cationic pullulan derivatives ab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da0cac9565abbb2e1399fd791d5f1f4d
https://hal.archives-ouvertes.fr/hal-03022444