Interplay between enterohaemorrhagic Escherichia coli and nitric oxide during the infectious process

Autor: Ilham Naïli, Marion Gardette, Annie Garrivier, Julien Daniel, Mickaël Desvaux, Mariagrazia Pizza, Alain Gobert, Thierry Marchal, Estelle Loukiadis, Grégory Jubelin

Publikováno v: Emerging Microbes and Infections, Vol 9, Iss 1, Pp 1065-1076 (2020)

ABSTRACTEnterohaemorrhagic Escherichia coli (EHEC) are bacterial pathogens responsible for life-threatening diseases in humans such as bloody diarrhoea and the hemolytic and uremic syndrome. To date, no specific therapy is available and treatments re

Externí odkaz: https://doaj.org/article/5b574010f23a484a98a6816889a83660

Spatially localized expression of glutamate decarboxylase gadB in Escherichia coli O157:H7 microcolonies in hydrogel matrix

Autor: Cédric Saint Martin, Nelly Caccia, Maud Darsonval, Marina Grégoire, Arthur Combeau, Grégory Jubelin, Florence Dubois-Brissonnet, Sabine Leroy, Romain Briandet, Mickaël Desvaux

Functional diversity within isogenic spatially organized bacterial populations has been shown to trigger emergent community properties such as stress tolerance. Taking advantage of confocal laser scanning microscopy combined with a transcriptional fl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d1d11113626f53d361e828a87180403
https://hal.inrae.fr/hal-03993592/document

Factors Involved in the Persistence of a Shiga Toxin-Producing Escherichia coli O157:H7 Strain in Bovine Feces and Gastro-Intestinal Content

Autor: Audrey Segura, Pauline Auffret, Delphine Bibbal, Marine Bertoni, Alexandra Durand, Grégory Jubelin, Monique Kérourédan, Hubert Brugère, Yolande Bertin, Evelyne Forano

Publikováno v: Frontiers in Microbiology, Vol 9 (2018)

Healthy cattle are the primary reservoir for O157:H7 Shiga toxin-producing E. coli responsible for human food-borne infections. Because farm environment acts as a source of cattle contamination, it is important to better understand the factors contro

Externí odkaz: https://doaj.org/article/f27550c4f1d14573a10fa2ecbff938ad

Genetic, physiological, and cellular heterogeneities of bacterial pathogens in food matrices: Consequences for food safety

Autor: Cédric Saint Martin, Grégory Jubelin, Maud Darsonval, Sabine Leroy, Charlène Leneveu‐Jenvrin, Ghaya Hmidene, Lysiane Omhover, Valérie Stahl, Laurent Guillier, Romain Briandet, Mickaël Desvaux, Florence Dubois‐Brissonnet

Publikováno v: Comprehensive Reviews in Food Science and Food Safety
Comprehensive Reviews in Food Science and Food Safety, 2022, 25 (1), pp.4294-4326. ⟨10.1111/1541-4337.13020⟩
Comprehensive Reviews in Food Science and Food Safety, Wiley, 2022, ⟨10.1111/1541-4337.13020⟩

International audience; In complex food systems, bacteria live in heterogeneous microstructures, and the population displays phenotypic heterogeneities at the single-cell level. This review provides an overview of spatiotemporal drivers of phenotypic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4972c1ffb95be9b64c7efcb4d1e2170a
https://hal.inrae.fr/hal-03762779/document

Mixed mucosal-parenteral immunizations with the broadly conserved pathogenic Escherichia coli antigen SslE induce a robust mucosal and systemic immunity without affecting the murine intestinal microbiota

Autor: Mariagrazia Pizza, Mickaël Desvaux, Grégory Jubelin, Juliette Vinot, Barbara Baudner, Ugo D'Oro, Annick Bernalier-Donadille, Cecilia Buonsanti, Ilham Naili

Publikováno v: Vaccine
Vaccine, 2019, 37 (2), pp.314-324. ⟨10.1016/j.vaccine.2018.10.008⟩
Vaccine, Elsevier, 2019, 37 (2), pp.314-324. ⟨10.1016/j.vaccine.2018.10.008⟩

International audience; Emergence and dissemination of multidrug resistance among pathogenic Escherichia coli have posed a serious threat to public health across developing and developed countries. In combination with a flexible repertoire of virulen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::491dec8874f57a985f7d1b36347f7a45
https://doi.org/10.1016/j.vaccine.2018.10.008