Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Grégoire Stik"'
Autor:
Marie Christou-Kent, Sergi Cuartero, Carla Garcia-Cabau, Julia Ruehle, Julian Naderi, Julia Erber, Maria Victoria Neguembor, Marcos Plana-Carmona, Marc Alcoverro-Bertran, Luisa De Andres-Aguayo, Antonios Klonizakis, Eric Julià-Vilella, Cian Lynch, Manuel Serrano, Denes Hnisz, Xavier Salvatella, Thomas Graf, Grégoire Stik
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112897- (2023)
Summary: Cell identity is orchestrated through an interplay between transcription factor (TF) action and genome architecture. The mechanisms used by TFs to shape three-dimensional (3D) genome organization remain incompletely understood. Here we prese
Externí odkaz:
https://doaj.org/article/f919872c3ea44338bf8df8ef1c78878a
Autor:
Bernard S. Stikker, Grégoire Stik, Antoinette F. van Ouwerkerk, Lianne Trap, Salvatore Spicuglia, Rudi W. Hendriks, Ralph Stadhouders
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-10 (2022)
Abstract Genome-wide association studies have identified 3p21.31 as the main risk locus for severe COVID-19, although underlying mechanisms remain elusive. We perform an epigenomic dissection of 3p21.31, identifying a CTCF-dependent tissue-specific 3
Externí odkaz:
https://doaj.org/article/c1a0d3a980af48e5a61bff91e9aff9ac
Publikováno v:
Nature reviews. Immunology.
Immune cell development and activation demand the precise and coordinated control of transcriptional programmes. Three-dimensional (3D) organization of the genome has emerged as an important regulator of chromatin state, transcriptional activity and
Autor:
Jinmi Choi, Kseniia Lysakovskaia, Gregoire Stik, Carina Demel, Johannes Söding, Tian V Tian, Thomas Graf, Patrick Cramer
Publikováno v:
eLife, Vol 10 (2021)
Enhancer activity drives cell differentiation and cell fate determination, but it remains unclear how enhancers cooperate during these processes. Here we investigate enhancer cooperation during transdifferentiation of human leukemia B-cells to macrop
Externí odkaz:
https://doaj.org/article/2e012031dc084c85b1add7b680e595bb