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Autor:
Grégoire P, Prévost, Marie O, Lonchampt, Susan, Holbeck, Samir, Attoub, Daniel, Zaharevitz, Mike, Alley, John, Wright, Marie C, Brezak, Hélène, Coulomb, Ann, Savola, Marion, Huchet, Sophie, Chaumeron, Quang-Dé, Nguyen, Patricia, Forgez, Erik, Bruyneel, Mark, Bracke, Eric, Ferrandis, Pierre, Roubert, Danièle, Demarquay, Christian, Gespach, Philip G, Kasprzyk
Publikováno v:
Cancer research. 66(18)
A large number of hormones and local agonists activating guanine-binding protein-coupled receptors (GPCR) play a major role in cancer progression. Here, we characterize the new imidazo-pyrazine derivative BIM-46174, which acts as a selective inhibito