A high cell density perfusion process for Modified Vaccinia virus Ankara production: Process integration with inline DNA digestion and cost analysis.

Autor: Gränicher G; Bioprocess Engineering Group, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany., Babakhani M; Bioprocess Engineering Group, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.; Chair for Bioprocess Engineering, Faculty of Process- and Systems Engineering, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany., Göbel S; Bioprocess Engineering Group, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.; Institute of Biochemical Engineering, Faculty 4 - Energy-, Process- and Bio-Engineering, University of Stuttgart, Stuttgart, Germany., Jordan I; ProBioGen AG, Berlin, Germany., Marichal-Gallardo P; Bioprocess Engineering Group, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany., Genzel Y; Bioprocess Engineering Group, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany., Reichl U; Bioprocess Engineering Group, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.; Chair for Bioprocess Engineering, Faculty of Process- and Systems Engineering, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.

Publikováno v: Biotechnology and bioengineering [Biotechnol Bioeng] 2021 Dec; Vol. 118 (12), pp. 4720-4734. Date of Electronic Publication: 2021 Sep 23.

Application of an Inclined Settler for Cell Culture-Based Influenza A Virus Production in Perfusion Mode

Autor: Coronel, J., Gränicher, G., Sandig, V., Noll, T., Genzel, Y., Reichl, U.

Publikováno v: Frontiers in Bioengineering and Biotechnology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1874::cf2f15c4462ec052d36954c95ecd5e43
https://hdl.handle.net/21.11116/0000-0006-DF07-821.11116/0000-0006-DF09-6

Application of an Inclined Settler for Cell Culture-Based Influenza A Virus Production in Perfusion Mode.

Autor: Coronel J; Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany., Gränicher G; Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany., Sandig V; ProBioGen AG, Berlin, Germany., Noll T; Institute of Cell Culture Technology, Bielefeld University, Bielefeld, Germany., Genzel Y; Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany., Reichl U; Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.; Bioprocess Engineering, Otto von Guericke University Magdeburg, Magdeburg, Germany.

Publikováno v: Frontiers in bioengineering and biotechnology [Front Bioeng Biotechnol] 2020 Jul 02; Vol. 8, pp. 672. Date of Electronic Publication: 2020 Jul 02 (Print Publication: 2020).

Perfusion Control for High Cell Density Cultivation and Viral Vaccine Production.

Autor: Nikolay A; Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany. a.nikolay@univercells.com., Bissinger T; Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany., Gränicher G; Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany., Wu Y; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China., Genzel Y; Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany., Reichl U; Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.; Bioprocess Engineering, Otto von Guericke University Magdeburg, Magdeburg, Germany.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2020; Vol. 2095, pp. 141-168.

Efficient influenza A virus production in high cell density using the novel porcine suspension cell line PBG.PK2.1.

Autor: Gränicher G; Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Sandtorstr. 1, 39106 Magdeburg, Germany. Electronic address: graenicher@mpi-magdeburg.mpg.de., Coronel J; Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Sandtorstr. 1, 39106 Magdeburg, Germany., Pralow A; Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Sandtorstr. 1, 39106 Magdeburg, Germany., Marichal-Gallardo P; Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Sandtorstr. 1, 39106 Magdeburg, Germany., Wolff M; Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Sandtorstr. 1, 39106 Magdeburg, Germany; Institute of Bioprocess Engineering and Pharmaceutical Technology, University of Applied Sciences Mittelhessen, Wiesenstrasse 14, 35390 Gießen, Germany., Rapp E; Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Sandtorstr. 1, 39106 Magdeburg, Germany., Karlas A; ProBioGen AG, Goethestr. 54, 13086 Berlin, Germany., Sandig V; ProBioGen AG, Goethestr. 54, 13086 Berlin, Germany., Genzel Y; Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Sandtorstr. 1, 39106 Magdeburg, Germany., Reichl U; Max Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, Sandtorstr. 1, 39106 Magdeburg, Germany; Chair for Bioprocess Engineering, Otto-von-Guericke-University Magdeburg, Universitätsplatz 2, 39106 Magdeburg, Germany.

Publikováno v: Vaccine [Vaccine] 2019 Nov 08; Vol. 37 (47), pp. 7019-7028. Date of Electronic Publication: 2019 Apr 17.