Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Gpr65"'
Autor:
Shamin Li, Fabien Melchiore, Chahrazade Kantari-Mimoun, Aurore Mouton, Samantha Knockaert, Wendy Philippon, Benjamin Chanrion, Christophe Bourgeois, Céline Lefebvre, Jamila Elhmouzi-Younes, Véronique Blanc, Fernando Ramon Olayo, Bruno Laugel
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The success of cancer immunotherapies such as immune checkpoint inhibitors, CAR T-cells and immune cell engagers have provided clinicians with tools to bypass some of the limitations of cancer immunity. However, numerous tumour factors curtail the im
Externí odkaz:
https://doaj.org/article/f077140e624c4dffa6743541f972e6ea
Autor:
Chaolong Yan, Zijiang Yang, Pin Chen, Yuyang Yeh, Chongjing Sun, Tao Xie, Wei Huang, Xiaobiao Zhang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background Lactate has emerged as a critical regulator within the tumor microenvironment, including glioma. However, the precise mechanisms underlying how lactate influences the communication between tumor cells and tumor-associated macropha
Externí odkaz:
https://doaj.org/article/d8462d44bc8c4c69908356dc9618f57f
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background GPR65 is a pH-sensing G-protein-coupled receptor that acts as a key innate immune checkpoint in the human tumor microenvironment, inhibiting the release of inflammatory factors and inducing significant upregulation of tissue repai
Externí odkaz:
https://doaj.org/article/9b67b974fca3403dbd2503fbcfc973e2
Autor:
Kun Zhang, Meng-Xia Zhang, Xiao-Xiang Meng, Jing Zhu, Jia-Jun Wang, Yi-Fan He, Ye-Hua Li, Si-Cong Zhao, Zhe-Min Shi, Li-Na Zheng, Tao Han, Wei Hong
Publikováno v:
Military Medical Research, Vol 10, Iss 1, Pp 1-21 (2023)
Abstract Background G-protein coupled receptors (GPCRs) are recognized as attractive targets for drug therapy. However, it remains poorly understood how GPCRs, except for a few chemokine receptors, regulate the progression of liver fibrosis. Here, we
Externí odkaz:
https://doaj.org/article/246eabfc1d1440e5a16cbdf89e355e28
Autor:
Jia Mao, Ying Feng, Yayun Zheng, Yaqiu Gao, Linyu Zhang, Xinrui Sun, Yilun Wu, Xiaofeng Zhu, Fang Ma
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Extravillous trophoblasts (EVTs) are essential cells during the formation of the placenta, with the major function of invading the maternal decidua, anchoring the developing placenta to the uterus, remodeling uterine arteries, and
Externí odkaz:
https://doaj.org/article/b8da16a0edef4f77ae2a63eebb285679
Autor:
Gengfeng Li, Jian Lin, Xiang Gao, Huiling Su, Ritian Lin, Han Gao, Zhongsheng Feng, Huili Wu, Baisui Feng, Keqiang Zuo, Yingchuan Li, Wei Wu, Leilei Fang, Zhanju Liu
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTIntestinal epithelial cell (IEC) regulation of barrier function and mucosal homeostasis enables the establishment of a harmonious gut microenvironment. However, host-derived regulatory networks that modulate intestinal antimicrobial defenses
Externí odkaz:
https://doaj.org/article/b6d071b3a3144e2b808f120118e04a6e
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Liangliang Wang, Lele Sun, Hao Sun, Yunhong Xing, Shidong Zhou, Guoshuai An, Jian Li, Kang Ren, Junhong Sun
Publikováno v:
Heliyon, Vol 9, Iss 2, Pp e13617- (2023)
It has been reported that inhibition of GPR65 may be effective for the treatment of certain cancers. Nevertheless, the role of GPR65 in various cancers remains unknown. We conducted an exhaustive pan-cancer analysis of GPR65 using multiple databases,
Externí odkaz:
https://doaj.org/article/a27339adf52a4bb7b9e267d6bb615525