Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Gp, glycoprotein"'
Autor:
Muhammed Iraqi, Avishay Edri, Yariv Greenshpan, Kiran Kundu, Priyanka Bolel, Avishag Cahana, Aner Ottolenghi, Roi Gazit, Leslie Lobel, Alex Braiman, Angel Porgador
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
The Ebola Virus (EBOV) glycoprotein (GP) sterically shields cell-membrane ligands to immune receptors such as human leukocyte antigen class-1 (HLA-I) and MHC class I polypeptide-related sequence A (MICA), thus mediating immunity evasion. It was sugge
Externí odkaz:
https://doaj.org/article/f3f8de4b72e44b37a2d8c0c465056e59
Autor:
Esraa Aly, Willias Masocha
Publikováno v:
IBRO Neuroscience Reports, Vol 10, Iss, Pp 109-118 (2021)
IBRO Neuroscience Reports
IBRO Neuroscience Reports
Human immunodeficiency virus (HIV) infection and antiretroviral therapy can independently induce HIV-associated neuropathic pain (HIV-NP). There is a dearth of drugs or therapeutic modalities that can alleviate HIV-NP. Smoked cannabis has been report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c16db2388b6b279018947fac8a0af7f
http://www.sciencedirect.com/science/article/pii/S2667242121000051
http://www.sciencedirect.com/science/article/pii/S2667242121000051
Autor:
Deborah Pushparajah, Salma Jimenez, Shirley Wong, Hibah Alattas, Roderick A. Slavcev, Nafiseh Nafissi
Publikováno v:
Advanced Drug Delivery Reviews
The novel betacoronavirus, SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), has spread across the globe at an unprecedented rate since its first emergence in Wuhan City, China in December 2019. Scientific communities around the world hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94880f08a67e236cd51c7dda2e6ac22e
http://europepmc.org/articles/PMC7789827
http://europepmc.org/articles/PMC7789827
Autor:
Fizzah Choudry, Daniel A. Jones, Charles Knight, Krishnaraj S. Rathod, Simon Woldman, Stephen Hamshere, Ajay Jain, Mohammed M Akhtar, Anthony Mathur, Oliver P Guttmann, Andreas Baumbach, R. Andrew Archbold
Publikováno v:
Journal of the American College of Cardiology
Background Coronavirus disease-2019 (COVID-19) is thought to predispose patients to thrombotic disease. To date there are few reports of ST-segment elevation myocardial infarction (STEMI) caused by type 1 myocardial infarction in patients with COVID-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::124944661435dea4ebfa29182992d3ee
https://doi.org/10.1016/j.jacc.2020.07.022
https://doi.org/10.1016/j.jacc.2020.07.022
Autor:
Ian A. Wilson, Robyn L. Stanfield
Publikováno v:
The Journal of Biological Chemistry
Fifty years ago, the first landmark structures of antibodies heralded the dawn of structural immunology. Momentum then started to build toward understanding how antibodies could recognize the vast universe of potential antigens and how antibody-combi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::104767baebed80d10c1c993cb1944741
https://pubmed.ncbi.nlm.nih.gov/33957119
https://pubmed.ncbi.nlm.nih.gov/33957119
Autor:
Paul Gale
Publikováno v:
Microbial Risk Analysis
Highlights • Dose-response model for pathogen infection developed on basis of thermodynamic association constants. • Fraction of pathogen oral dose surviving mucus barrier to reach intestinal epithelium modelled. • Fraction of host intestinal e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faca9ed68b4ea8e4bf6d483b37b4c524
http://europepmc.org/articles/PMC7103988
http://europepmc.org/articles/PMC7103988
Publikováno v:
Cellular Immunology
Highlights • EBOV sGP inhibits cytokine production of macrophages but not monocytes. • Polarization of macrophages into M1 and M2 phenotypes are not affected by sGP. • EBOV sGP inhibits pro-inflammatory but not anti-inflammatory cytokine produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb87610592557c850a0296455261d2f9
http://europepmc.org/articles/PMC7094302
http://europepmc.org/articles/PMC7094302
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 8, Iss 2, Pp 200-208 (2018)
Acta Pharmaceutica Sinica B
Acta Pharmaceutica Sinica B, Vol 8, Iss 2, Pp 200-208 (2018)
Acta Pharmaceutica Sinica B
Filoviruses cause severe and fatal viral hemorrhagic fever in humans. Filovirus research has been extensive since the 2014 Ebola outbreak. Due to their high pathogenicity and mortality, live filoviruses require Biosafety Level-4 (BSL-4) facilities, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ec3033eee800fdb9e828320bcb0d27
http://europepmc.org/articles/PMC5925413
http://europepmc.org/articles/PMC5925413
Autor:
Christopher L. Cooper, Sina Bavari, Jesse T. Steffens, Sean A. Van Tongeren, Steven A. Kwilas, Karen A. Martins, Sarah L. Norris, Sabrina M. Stronsky, Jacqueline G. Benko
Publikováno v:
EBioMedicine, Vol 3, Iss C, Pp 67-78 (2016)
EBioMedicine
EBioMedicine
Protein-based vaccines offer a safer alternative to live-attenuated or inactivated vaccines but have limited immunogenicity. The identification of adjuvants that augment immunogenicity, specifically in a manner that is durable and antigen-specific, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee8a95f3c2fc7d0cc4ff1433fe2e9ce
Publikováno v:
Biochemical Journal
Rho GTPases are critical for platelet function. Although the roles of RhoA, Rac and Cdc42 are characterized, platelets express other Rho GTPases, whose activities are less well understood. This review summarizes our understanding of the roles of plat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8dee12c58f70730a3a55910e7d6987a6
http://europepmc.org/articles/PMC4357237
http://europepmc.org/articles/PMC4357237