Introduction to System Dynamics Modeling with DYNAMO

Autor: D. C. Lane, GP Richardson, AL Pugh III

Publikováno v: The Journal of the Operational Research Society. 48:1146

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ab17f49d0a4b60e3e38826ca072f8d26
https://doi.org/10.2307/3010312

Large-scale annotated dataset for cochlear hair cell detection and classification.

Autor: Buswinka CJ; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA.; Department of Otolaryngology, Head and Neck Surgery, Harvard Medical School, Boston, MA, 02114, USA.; Speech and Hearing Biosciences and Technology graduate program, Harvard University, Cambridge, MA, 02138, USA., Rosenberg DB; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA.; Department of Otolaryngology, Head and Neck Surgery, Harvard Medical School, Boston, MA, 02114, USA.; Department of Cell and Developmental Biology, University of California San Diego, La Jolla, CA, 92093, USA., Simikyan RG; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA., Osgood RT; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA.; Department of Otolaryngology, Head and Neck Surgery, Harvard Medical School, Boston, MA, 02114, USA.; Sussex Neuroscience, School of Life Sciences, University of Sussex, Brighton, UK., Fernandez K; Section on Sensory Cell Biology, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, 20814, USA., Nitta H; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA., Hayashi Y; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA.; Department of Otolaryngology, Head and Neck Surgery, Harvard Medical School, Boston, MA, 02114, USA., Liberman LW; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA.; Department of Otolaryngology, Head and Neck Surgery, Harvard Medical School, Boston, MA, 02114, USA., Nguyen E; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA., Yildiz E; Department of Otolaryngology, Head and Neck Surgery, Vienna General Hospital and Medical University of Vienna, 1090, Vienna, Austria., Kim J; Department of Otolaryngology, Washington University School of Medicine, St. Louis, MO, 63110, USA.; Department of Neuroscience, Washington University School of Medicine, St. Louis, MO, 63110, USA.; Department of Otolaryngology, Stanford University School of Medicine, Stanford, CA, 94305, USA., Jarysta A; The Jackson Laboratory, Bar Harbor, ME, 04609, USA., Renauld J; Department of Otolaryngology-Head and Neck Surgery, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Wesson E; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA., Wang H; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA.; Department of Otolaryngology, Head and Neck Surgery, Harvard Medical School, Boston, MA, 02114, USA., Thapa P; The University of Mississippi Medical Center, Department of Otolaryngology - Head and Neck Surgery, Jackson, MS, 39216, USA., Bordiga P; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA.; Department of Otolaryngology, Head and Neck Surgery, Harvard Medical School, Boston, MA, 02114, USA., McMurtry N; Department of Otolaryngology-Head and Neck Surgery, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Llamas J; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research, University of Southern California, Los Angeles, CA, 90033, USA.; Tina and Rick Caruso Department of Otolaryngology-Head and Neck Surgery, University of Southern California, Los Angeles, CA, 90033, USA., Kitcher SR; Sussex Neuroscience, School of Life Sciences, University of Sussex, Brighton, UK., López-Porras AI; Department of Physiology, University of Kentucky, Lexington, KY, 40536, USA., Cui R; Section on Sensory Physiology and Biophysics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, 20814, USA., Behnammanesh G; Department of Pharmacology and Therapeutics, University of Florida, Gainesville, FL, 32610, USA., Bird JE; Department of Pharmacology and Therapeutics, University of Florida, Gainesville, FL, 32610, USA., Ballesteros A; Section on Sensory Physiology and Biophysics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, 20814, USA., Vélez-Ortega AC; Department of Physiology, University of Kentucky, Lexington, KY, 40536, USA., Edge ASB; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA.; Department of Otolaryngology, Head and Neck Surgery, Harvard Medical School, Boston, MA, 02114, USA., Deans MR; Department of Neurobiology, Spencer Fox Eccles School of Medicine at the University of Utah, Salt Lake City, UT, 84112, USA.; Department of Otolaryngology - Head & Neck Surgery, Spencer Fox Eccles School of Medicine at the University of Utah, Salt Lake City, UT, 84132, USA., Gnedeva K; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research, University of Southern California, Los Angeles, CA, 90033, USA.; Tina and Rick Caruso Department of Otolaryngology-Head and Neck Surgery, University of Southern California, Los Angeles, CA, 90033, USA., Shrestha BR; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA.; Department of Otolaryngology, Head and Neck Surgery, Harvard Medical School, Boston, MA, 02114, USA., Manor U; Department of Cell and Developmental Biology, University of California San Diego, La Jolla, CA, 92093, USA.; Waitt Advanced Biophotonics Center, Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA, 92037, USA., Zhao B; Department of Otolaryngology-Head and Neck Surgery, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Ricci AJ; Department of Neuroscience, Washington University School of Medicine, St. Louis, MO, 63110, USA.; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, 94305, USA., Tarchini B; The Jackson Laboratory, Bar Harbor, ME, 04609, USA.; Tufts University School of Medicine, Boston, 02111, MA, USA.; Graduate School of Biomedical Science and Engineering (GSBSE), University of Maine, Orono, ME, 04469, USA., Basch ML; Department of Otolaryngology-Head and Neck Surgery, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Stepanyan R; Department of Otolaryngology-Head and Neck Surgery, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.; Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Landegger LD; Department of Otolaryngology, Head and Neck Surgery, Vienna General Hospital and Medical University of Vienna, 1090, Vienna, Austria.; Department of Otolaryngology, Stanford University School of Medicine, Stanford, CA, 94305, USA., Rutherford MA; Department of Otolaryngology, Washington University, 660 S. Euclid Avenue, Campus Box 8115, St. Louis, MO, 63110, USA., Liberman MC; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA.; Department of Otolaryngology, Head and Neck Surgery, Harvard Medical School, Boston, MA, 02114, USA.; Speech and Hearing Biosciences and Technology graduate program, Harvard University, Cambridge, MA, 02138, USA., Walters BJ; The University of Mississippi Medical Center, Department of Otolaryngology - Head and Neck Surgery, Jackson, MS, 39216, USA., Kros CJ; Sussex Neuroscience, School of Life Sciences, University of Sussex, Brighton, UK., Richardson GP; Sussex Neuroscience, School of Life Sciences, University of Sussex, Brighton, UK., Cunningham LL; Section on Sensory Cell Biology, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, 20814, USA., Indzhykulian AA; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA. artur_indzhykulian@hms.harvard.edu.; Department of Otolaryngology, Head and Neck Surgery, Harvard Medical School, Boston, MA, 02114, USA. artur_indzhykulian@hms.harvard.edu.; Speech and Hearing Biosciences and Technology graduate program, Harvard University, Cambridge, MA, 02138, USA. artur_indzhykulian@hms.harvard.edu.

Publikováno v: Scientific data [Sci Data] 2024 Apr 23; Vol. 11 (1), pp. 416. Date of Electronic Publication: 2024 Apr 23.

Large-scale annotated dataset for cochlear hair cell detection and classification.

Autor: Buswinka CJ; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA.; Department of Otolaryngology, Head and Neck Surgery, Harvard Medical School, Boston, MA, 02114, USA.; Speech and Hearing Biosciences and Technology graduate program, Harvard University, Cambridge, MA, 02138, USA., Rosenberg DB; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA., Simikyan RG; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA., Osgood RT; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA.; Department of Otolaryngology, Head and Neck Surgery, Harvard Medical School, Boston, MA, 02114, USA.; Sussex Neuroscience, School of Life Sciences, University of Sussex, Brighton, United Kingdom., Fernandez K; Section on Sensory Cell Biology, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, 20814, USA., Nitta H; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA., Hayashi Y; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA.; Department of Otolaryngology, Head and Neck Surgery, Harvard Medical School, Boston, MA, 02114, USA., Liberman LW; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA.; Department of Otolaryngology, Head and Neck Surgery, Harvard Medical School, Boston, MA, 02114, USA., Nguyen E; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA., Yildiz E; Department of Otolaryngology, Head and Neck Surgery, Vienna General Hospital and Medical University of Vienna, 1090 Vienna, Austria., Kim J; Department of Otolaryngology, Washington University School of Medicine, St. Louis, MO, USA.; Department of Neuroscience, Washington University School of Medicine, St. Louis, MO, USA.; Department of Otolaryngology, Stanford University School of Medicine, Stanford, CA, 94305, USA., Jarysta A; The Jackson Laboratory, Bar Harbor, ME, 04609, USA., Renauld J; Department of Otolaryngology-Head and Neck Surgery, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Wesson E; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA., Thapa P; The University of Mississippi Medical Center, Dept. of Otolaryngology - Head and Neck Surgery, Jackson, MS, USA., Bordiga P; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA.; Department of Otolaryngology, Head and Neck Surgery, Harvard Medical School, Boston, MA, 02114, USA., McMurtry N; Department of Otolaryngology-Head and Neck Surgery, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Llamas J; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research, University of Southern California, Los Angeles, CA, 90033, USA.; Tina and Rick Caruso Department of Otolaryngology-Head and Neck Surgery, University of Southern California, Los Angeles, CA, 90033, USA., Kitcher SR; Sussex Neuroscience, School of Life Sciences, University of Sussex, Brighton, United Kingdom., López-Porras AI; Department of Physiology, University of Kentucky, Lexington, KY, 40536, USA., Cui R; Section on Sensory Physiology and Biophysics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, 20814, USA., Behnammanesh G; Department of Pharmacology and Therapeutics, University of Florida, Gainesville, FL, 32610, USA; Myology Institute, University of Florida, Gainesville, FL, 32610, USA., Bird JE; Department of Pharmacology and Therapeutics, University of Florida, Gainesville, FL, 32610, USA; Myology Institute, University of Florida, Gainesville, FL, 32610, USA., Ballesteros A; Section on Sensory Physiology and Biophysics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, 20814, USA., Vélez-Ortega AC; Department of Physiology, University of Kentucky, Lexington, KY, 40536, USA., Edge AS; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA.; Department of Otolaryngology, Head and Neck Surgery, Harvard Medical School, Boston, MA, 02114, USA., Deans MR; Department of Neurobiology, Spencer Fox Eccles School of Medicine at the University of Utah, Salt Lake City, UT 84112, USA.; Department of Otolaryngology - Head & Neck Surgery, Spencer Fox Eccles School of Medicine at the University of Utah, Salt Lake City, UT, 84132, USA., Gnedeva K; Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research, University of Southern California, Los Angeles, CA, 90033, USA.; Tina and Rick Caruso Department of Otolaryngology-Head and Neck Surgery, University of Southern California, Los Angeles, CA, 90033, USA., Shrestha BR; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA.; Department of Otolaryngology, Head and Neck Surgery, Harvard Medical School, Boston, MA, 02114, USA., Manor U; Waitt Advanced Biophotonics Center, Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA, 92037, USA.; Department of Cell and Developmental Biology, University of California San Diego, La Jolla, CA, 92093., Zhao B; Department of Otolaryngology-Head and Neck Surgery, Indiana University School of Medicine, Indianapolis, IN, 46202, USA., Ricci AJ; Department of Otolaryngology, Stanford University School of Medicine, Stanford, CA, 94305, USA.; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, 94305, USA., Tarchini B; The Jackson Laboratory, Bar Harbor, ME, 04609, USA.; Department of Medicine, Tufts University, Boston, 02111, MA, USA.; Graduate School of Biomedical Science and Engineering (GSBSE), University of Maine, Orono, ME, 04469, USA., Basch M; Department of Otolaryngology-Head and Neck Surgery, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Stepanyan RS; Department of Otolaryngology-Head and Neck Surgery, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.; Department of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Landegger LD; Department of Otolaryngology, Head and Neck Surgery, Vienna General Hospital and Medical University of Vienna, 1090 Vienna, Austria., Rutherford M; Department of Otolaryngology, Washington University, 660 S. Euclid Avenue, Campus Box 8115, St. Louis, MO, 63110, USA., Liberman MC; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA.; Department of Otolaryngology, Head and Neck Surgery, Harvard Medical School, Boston, MA, 02114, USA.; Speech and Hearing Biosciences and Technology graduate program, Harvard University, Cambridge, MA, 02138, USA., Walters BJ; The University of Mississippi Medical Center, Dept. of Otolaryngology - Head and Neck Surgery, Jackson, MS, USA., Kros CJ; Sussex Neuroscience, School of Life Sciences, University of Sussex, Brighton, United Kingdom., Richardson GP; Sussex Neuroscience, School of Life Sciences, University of Sussex, Brighton, United Kingdom., Cunningham LL; Section on Sensory Cell Biology, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, MD, 20814, USA., Indzhykulian AA; Eaton Peabody Laboratories, Mass Eye and Ear, Boston, MA, 02114, USA.; Department of Otolaryngology, Head and Neck Surgery, Harvard Medical School, Boston, MA, 02114, USA.; Speech and Hearing Biosciences and Technology graduate program, Harvard University, Cambridge, MA, 02138, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Sep 01. Date of Electronic Publication: 2023 Sep 01.

A critical period of prehearing spontaneous Ca ²⁺ spiking is required for hair-bundle maintenance in inner hair cells.

Autor: Carlton AJ; School of Biosciences, University of Sheffield, Sheffield, UK., Jeng JY; School of Biosciences, University of Sheffield, Sheffield, UK., Grandi FC; Gladstone Institute of Neurological Disease, San Francisco, CA, USA., De Faveri F; School of Biosciences, University of Sheffield, Sheffield, UK., Ceriani F; School of Biosciences, University of Sheffield, Sheffield, UK., De Tomasi L; School of Biosciences, University of Sheffield, Sheffield, UK., Underhill A; School of Biosciences, University of Sheffield, Sheffield, UK., Johnson SL; School of Biosciences, University of Sheffield, Sheffield, UK.; Neuroscience Institute, University of Sheffield, Sheffield, UK., Legan KP; School of Life Sciences, University of Sussex, Falmer, Brighton, UK., Kros CJ; School of Life Sciences, University of Sussex, Falmer, Brighton, UK., Richardson GP; School of Life Sciences, University of Sussex, Falmer, Brighton, UK., Mustapha M; School of Biosciences, University of Sheffield, Sheffield, UK.; Neuroscience Institute, University of Sheffield, Sheffield, UK., Marcotti W; School of Biosciences, University of Sheffield, Sheffield, UK.; Neuroscience Institute, University of Sheffield, Sheffield, UK.

Publikováno v: The EMBO journal [EMBO J] 2023 Feb 15; Vol. 42 (4), pp. e112118. Date of Electronic Publication: 2023 Jan 03.

Identification of a series of hair-cell MET channel blockers that protect against aminoglycoside-induced ototoxicity.

Autor: Kenyon EJ; Sussex Neuroscience and., Kirkwood NK; Sussex Neuroscience and., Kitcher SR; Sussex Neuroscience and., Goodyear RJ; Sussex Neuroscience and., Derudas M; Sussex Drug Discovery Centre, School of Life Sciences, and., Cantillon DM; Global Health and Infection, Brighton and Sussex Medical School, University of Sussex, Brighton, United Kingdom., Baxendale S; Bateson Centre and Department of Biomedical Science, and., de la Vega de León A; Information School, University of Sheffield, Sheffield, United Kingdom., Mahieu VN; Sussex Neuroscience and., Osgood RT; Sussex Neuroscience and., Wilson CD; Sussex Neuroscience and., Bull JC; Department of Biosciences, College of Science, Swansea University, Swansea, United Kingdom., Waddell SJ; Global Health and Infection, Brighton and Sussex Medical School, University of Sussex, Brighton, United Kingdom., Whitfield TT; Bateson Centre and Department of Biomedical Science, and., Ward SE; Medicines Discovery Institute, Cardiff University, Cardiff, United Kingdom., Kros CJ; Sussex Neuroscience and., Richardson GP; Sussex Neuroscience and.

Publikováno v: JCI insight [JCI Insight] 2021 Apr 08; Vol. 6 (7). Date of Electronic Publication: 2021 Apr 08.