Expression of CD56 by human papillomavirus E7-specific CD8+ cytotoxic T lymphocytes correlates with increased intracellular perforin expression and enhanced cytotoxicity against HLA-A2-matched cervical tumor cells

Autor: Ad, Santin, Pl, Hermonat, Antonella Ravaggi, Bellone S, Jj, Roman, Jayaprabhu S, Pecorelli S, Gp, Parham, Mj, Cannon

Publikováno v: Europe PubMed Central

Human papillomavirus (HPV) infection represents the most important risk factor for developing cervical cancer. In this study, we examine the potential of full-length E7-pulsed autologous dendritic cells (DCs) to induce antigen-specific CTL responses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9a840b3a09a48d7736722eee15e14349
http://europepmc.org/abstract/med/11300476

Development, characterization and distribution of adoptively transferred peripheral blood lymphocytes primed by human papillomavirus 18 E7--pulsed autologous dendritic cells in a patient with metastatic adenocarcinoma of the uterine cervix

Autor: Ad, Santin, Pl, Hermonat, Antonella Ravaggi, Bellone S, Cowan C, Korourian S, Pecorelli S, Mj, Cannon, Gp, Parham

Publikováno v: Europe PubMed Central

We describe a 27-year-old woman with systemic chemoresistant and radioresistant metastatic disease secondary to a recurrence of human papillomavirus (HPV) 18 infected cervical adenocarcinoma of the uterine cervix who received adoptive transfer of per

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b5785209ba0d4d70a72ba85ee2b6c421
http://europepmc.org/abstract/med/10726612

A portable thermal ablation device for cervical cancer prevention in a screen-and-treat setting: a randomized, noninferiority trial.

Autor: Basu P; Early Detection, Prevention & Infections Branch, International Agency for Research on Cancer, Lyon, France. basup@iarc.who.int., Mwanahamuntu M; Department of Obstetrics and Gynecology, University Teaching Hospital, Lusaka, Zambia., Pinder LF; Department of Obstetrics and Gynecology, University Teaching Hospital, Lusaka, Zambia., Muwonge R; Early Detection, Prevention & Infections Branch, International Agency for Research on Cancer, Lyon, France., Lucas E; Early Detection, Prevention & Infections Branch, International Agency for Research on Cancer, Lyon, France., Nyambe N; Department of Obstetrics and Gynecology, University Teaching Hospital, Lusaka, Zambia., Chisele S; Department of Obstetrics and Gynecology, University Teaching Hospital, Lusaka, Zambia., Shibemba AL; Department of Pathology, University Teaching Hospital, Lusaka, Zambia., Sauvaget C; Early Detection, Prevention & Infections Branch, International Agency for Research on Cancer, Lyon, France., Sankaranarayanan R; Karkinos Healthcare, Kerala Operations, Ernakulam, India., Prendiville W; Early Detection, Prevention & Infections Branch, International Agency for Research on Cancer, Lyon, France., Parham GP; Department of Obstetrics and Gynecology, University Teaching Hospital, Lusaka, Zambia.

Publikováno v: Nature medicine [Nat Med] 2024 Sep; Vol. 30 (9), pp. 2596-2604. Date of Electronic Publication: 2024 Jun 25.

Internal validation of Automated Visual Evaluation (AVE) on smartphone images for cervical cancer screening in a prospective study in Zambia.

Autor: Hu L; Global Health Labs, Inc., Bellevue, Washington, USA., Mwanahamuntu MH; University Teaching Hospital, Lusaka, Zambia., Sahasrabuddhe VV; National Cancer Institute, NIH, Bethesda, Maryland, USA., Barrett C; Clinton Health Access Initiative (CHAI), Inc.,, Boston, Massachusetts, USA., Horning MP; Global Health Labs, Inc., Bellevue, Washington, USA., Shah I; Global Health Labs, Inc., Bellevue, Washington, USA., Laverriere Z; Global Health Labs, Inc., Bellevue, Washington, USA., Banik D; Global Health Labs, Inc., Bellevue, Washington, USA., Ji Y; Global Health Labs, Inc., Bellevue, Washington, USA., Shibemba AL; University Teaching Hospital, Lusaka, Zambia., Chisele S; University Teaching Hospital, Lusaka, Zambia., Munalula MK; University Teaching Hospital, Lusaka, Zambia., Kaunga F; University Teaching Hospital, Lusaka, Zambia., Musonda F; University Teaching Hospital, Lusaka, Zambia., Malyangu E; University Teaching Hospital, Lusaka, Zambia., Hariharan KM; Clinton Health Access Initiative (CHAI), Inc.,, Boston, Massachusetts, USA., Parham GP; University Teaching Hospital, Lusaka, Zambia.; University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Publikováno v: Cancer medicine [Cancer Med] 2024 Jun; Vol. 13 (11), pp. e7355.

Improving access to safe, quality surgical care for gynecologic cancers through capacity-building interventions in low- and middle-income countries: A scoping review.

Autor: Hill SK; Program in Global Surgery and Social Change, Harvard Medical School, Boston, Massachusetts, USA., Bempong-Ahun N; The Global Surgery Foundation, Geneva, Switzerland., Okolo ID; Program in Global Surgery and Social Change, Harvard Medical School, Boston, Massachusetts, USA.; Royal Infirmary of Edinburgh, Edinburgh, Scotland, UK.; The Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, Massachusetts, USA., Lalla AT; The Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Obstetrics & Gynecology, Brigham and Women's Hospital, Boston, Massachusetts, USA., Worku D; Department of Obstetrics and Gynecology, University Teaching Hospital of Kigali (CHUK), Kigali, Rwanda., Asres T; Department of Obstetrics and Gynecology, Rwanda Military Hospital (RMH), Kigali, Rwanda., Philpotts L; Treadwell Library, Massachusetts General Hospital, Boston, Massachusetts, USA., Fallah PN; The Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Obstetrics & Gynecology, Brigham and Women's Hospital, Boston, Massachusetts, USA., Varallo J; The Global Surgery Foundation, Geneva, Switzerland., Corlew S; Program in Global Surgery and Social Change, Harvard Medical School, Boston, Massachusetts, USA., Kamfwa P; Department of Gynecologic Oncology, Cancer Diseases Hospital, Lusaka, Zambia., Parham GP; Women and Newborn Hospital-University Teaching Hospital, Lusaka, Zambia.; Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, USA., Hicks ML; Women and Newborn Hospital-University Teaching Hospital, Lusaka, Zambia.; Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, USA.; Department of Gynecologic Oncology, Michigan Cancer Institute, St. Joseph Mercy Oakland, Pontiac, USA., Ibbotson G; The Global Surgery Foundation, Geneva, Switzerland.; United Nations Institute for Training and Research, Geneva, Switzerland., Randall T; The Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, Massachusetts, USA.

Publikováno v: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics [Int J Gynaecol Obstet] 2024 May; Vol. 165 (2), pp. 552-561. Date of Electronic Publication: 2023 Nov 05.