Zobrazeno 1 - 10
of 454
pro vyhledávání: '"Gozoh TSUJIMOTO"'
Autor:
Déborah Ancel, Arnaud Bernard, Selvakumar Subramaniam, Akira Hirasawa, Gozoh Tsujimoto, Toshihiro Hashimoto, Patricia Passilly-Degrace, Naim-Akhtar Khan, Philippe Besnard
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 2, Pp 369-378 (2015)
Implication of the long-chain fatty acid (LCFA) receptor GPR120, also termed free fatty acid receptor 4, in the taste-guided preference for lipids is a matter of debate. To further unravel the role of GPR120 in the “taste of fat”, the present stu
Externí odkaz:
https://doaj.org/article/f9e5afadd8594f378d8fa1602c04c395
Autor:
Akira Nakajima, Akiho Nakatani, Sae Hasegawa, Junichiro Irie, Kentaro Ozawa, Gozoh Tsujimoto, Takayoshi Suganami, Hiroshi Itoh, Ikuo Kimura
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0179696 (2017)
The regulation of inflammatory responses within adipose tissue by various types of immune cells is closely related to tissue homeostasis and progression of metabolic disorders such as obesity and type 2 diabetes. G-protein-coupled receptor 43 (GPR43)
Externí odkaz:
https://doaj.org/article/5a10192d6ce24ff69b207060e3b0ff60
New Frontiers in Gut Nutrient Sensor Research: Free Fatty Acid Sensing in the Gastrointestinal Tract
Publikováno v:
Journal of Pharmacological Sciences, Vol 112, Iss 1, Pp 19-24 (2010)
Utilizing the human genome database, the recently developed G-protein–coupled receptors (GPCRs) deorphanizing strategy successfully identified multiple receptors of free fatty acids (FFAs). FFAs have been demonstrated to act as ligands of several G
Externí odkaz:
https://doaj.org/article/e0b30f8da0bd4ca0ae6e7674231a490c
Autor:
Taka-aki Koshimizu, Gozoh Tsujimoto
Publikováno v:
Journal of Pharmacological Sciences, Vol 109, Iss 1, Pp 33-37 (2009)
Arginine vasopressin (AVP) activates three vasopressin receptors and it also has an agonistic activity on the oxytocin receptor. For an accurate description of the target receptor subtype(s) responsible for complex AVP and oxytocin actions, a careful
Externí odkaz:
https://doaj.org/article/cde1f6980a574c10863cbcc4e11a1f3d
Autor:
Yoshiyuki Takahara, Tomoko Kobayashi, Kazuhisa Takemoto, Tetsuya Adachi, Ken Osaki, Kozo Kawahara, Gozoh Tsujimoto
Publikováno v:
Journal of Pharmacological Sciences, Vol 107, Iss 1, Pp 1-7 (2008)
Genome-wide gene-expression data from DNA-microarray technology and molecular-network data from computational text-mining have led to a paradigm shift in biological research. However, interpretation of the huge amount of data is a bottleneck. We have
Externí odkaz:
https://doaj.org/article/1e64e5b74e204ab79bf4d96f98d84de8
Publikováno v:
Cancer Informatics, Vol 2, Pp 361-371 (2006)
An important issue in current medical science research is to find the genes that are strongly related to an inherited disease. A particular focus is placed on cancer-gene relations, since some types of cancers are inherited. As bio-medical databases
Externí odkaz:
https://doaj.org/article/466fe6a73bbb43d6823f243fb9156bee
Autor:
Yasukatsu Izumi, Yasuhiro Izumiya, Masayuki Shiota, Tokihito Yukimura, Satoshi Shiojima, Masateru Yamada, Tadashi Kadowaki, Susumu Katsuma, Akira Hirasawa, Gozoh Tsujimoto, Hiroshi Iwao
Publikováno v:
Journal of Pharmacological Sciences, Vol 96, Iss 1, Pp 91-94 (2004)
We analyzed gene expression in rat anti-Thy1 antibody-induced glomerulonephritis by using the cDNA microarray method. Ninety-seven genes that differed by more than 1.5-fold intensity in comparison with the controls were selected. Cluster analysis sho
Externí odkaz:
https://doaj.org/article/6edf9b9d08ed44e0a24a9d45676dae25
Trastuzumab produces therapeutic actions by upregulating miR-26a and miR-30b in breast cancer cells.
Autor:
Takehiro Ichikawa, Fumiaki Sato, Kazuya Terasawa, Soken Tsuchiya, Masakazu Toi, Gozoh Tsujimoto, Kazuharu Shimizu
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31422 (2012)
OBJECTIVE: Trastuzumab has been used for the treatment of HER2-positive breast cancer (BC). However, a subset of BC patients exhibited resistance to trastuzumab therapy. Thus, clarifying the molecular mechanism of trastuzumab treatment will be benefi
Externí odkaz:
https://doaj.org/article/3088fa258fa74a8a837ea4b4bf00008e
Autor:
Fumiaki Sato, Etsuro Hatano, Koji Kitamura, Akira Myomoto, Takeshi Fujiwara, Satoko Takizawa, Soken Tsuchiya, Gozoh Tsujimoto, Shinji Uemoto, Kazuharu Shimizu
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16435 (2011)
OBJECTIVE: Hepatocellular carcinoma (HCC) is difficult to manage due to the high frequency of post-surgical recurrence. Early detection of the HCC recurrence after liver resection is important in making further therapeutic options, such as salvage li
Externí odkaz:
https://doaj.org/article/28ecf2bf684b465989fbd238512c1d4b
Publikováno v:
Journal of Nucleic Acids, Vol 2011 (2011)
RNA interference (RNAi) is a powerful tool for studying gene function owing to the ease with which it can selectively silence genes of interest, and it has also attracted attention because of its potential for therapeutic applications. Chemically syn
Externí odkaz:
https://doaj.org/article/25a7a8b44cd8453d8c02522d9e4eac79