Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Gowtham Sathyanarayanan"'
Autor:
Abishek Wadhwa, Thomas R. Bobak, Lennart Bohrmann, Reka Geczy, Sathiya Sekar, Gowtham Sathyanarayanan, Jörg P. Kutter, Henrik Franzyk, Camilla Foged, Katayoun Saatchi, Urs O. Häfeli
Publikováno v:
OpenNano, Vol 13, Iss , Pp 100180- (2023)
Nanomedicines based on nanoparticles rely both on the potency of the drug as well as the efficiency of the delivery system, for which particle size plays a crucial role. For the intracellular delivery of small interference RNA (siRNA), lipid-polymer
Externí odkaz:
https://doaj.org/article/a24eb0be3e2c4dbe91a0350992d611c3
Autor:
Gowtham Sathyanarayanan, Mafalda Rodrigues, David Limón, Romén Rodriguez-Trujillo, Josep Puigmartí-Luis, Lluïsa Pérez-García, David B. Amabilino
Publikováno v:
ACS Omega, Vol 2, Iss 12, Pp 8849-8858 (2017)
Externí odkaz:
https://doaj.org/article/4a5762869b944a378f18320ac04bfe7c
Publikováno v:
Micromachines, Vol 9, Iss 12, p 649 (2018)
This work describes the interfacing of electrowetting-on-dielectric based digital microfluidic (DMF) sample preparation devices with ambient mass spectrometry (MS) via desorption atmospheric pressure photoionization (DAPPI). The DMF droplet manipulat
Externí odkaz:
https://doaj.org/article/7e046d0efdd44c7a982216783842cb8f
The superfamily of hepatic cytochrome P450 (CYP) enzymes is responsible for the intrinsic clearance of the majority of therapeutic drugs in humans. However, the kinetics of drug clearance via CYPs varies significantly among individuals due to both ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7326c5cfec2dd6a5051650c2020c2cd
http://hdl.handle.net/10138/335623
http://hdl.handle.net/10138/335623
Microfluidic sample manipulation is a key enabler in modern chemical biology research. Both discrete droplet-based digital microfluidic (DMF) assays and continuous flow in-channel assays are well established, each featuring unique advantages from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e51850e9950693e9f9e3ef5e3ca7550b
http://hdl.handle.net/10138/326664
http://hdl.handle.net/10138/326664
Autor:
Gowtham Sathyanarayanan
Publikováno v:
University of Helsinki
Drug metabolism is a detoxification process by which the body converts pharmaceuticals into more hydrophilic metabolites. Understanding of the drug metabolism process and metabolic profiling plays a vital role in drug development processes by ensurin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::aa2d5faac3251ce4c459728f6679ce94
http://hdl.handle.net/10138/318455
http://hdl.handle.net/10138/318455
Publikováno v:
Micromachines
Micromachines, Vol 9, Iss 12, p 649 (2018)
Volume 9
Issue 12
Micromachines, Vol 9, Iss 12, p 649 (2018)
Volume 9
Issue 12
This work describes the interfacing of electrowetting-on-dielectric based digital microfluidic (DMF) sample preparation devices with ambient mass spectrometry (MS) via desorption atmospheric pressure photoionization (DAPPI). The DMF droplet manipulat
Publikováno v:
Analytical and Bioanalytical Chemistry
We report the development and characterization of digital microfluidic (DMF) immobilized enzyme reactors (IMERs) for studying cytochrome P450 (CYP)-mediated drug metabolism on droplet scale. The on-chip IMERs consist of porous polymer (thiol-ene) mon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::330cc4cbda0b26f27e1543d9a112042c
http://hdl.handle.net/10138/245422
http://hdl.handle.net/10138/245422
Autor:
Josep Puigmartí-Luis, Romen Rodriguez-Trujillo, Lluïsa Pérez-García, David B. Amabilino, David Limón, Gowtham Sathyanarayanan, Mafalda Rodrigues
Publikováno v:
ACS Omega, Vol 2, Iss 12, Pp 8849-8858 (2017)
Dipòsit Digital de la UB
Universidad de Barcelona
ACS Omega, 2 (12)
ACS Omega
Dipòsit Digital de la UB
Universidad de Barcelona
ACS Omega, 2 (12)
ACS Omega
It is shown here that controlled mixing of a gelator, drug, solvent, and antisolvent in a microfluidic channel leads to faster setting gels and more robust materials with longer release profiles than the physical gels of the same composition obtained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::325134a5ec0c2adf15490c6f752a7427