Zobrazeno 1 - 10
of 298
pro vyhledávání: '"Gowtham K"'
Autor:
Bhargava Kotte, Naveen A, Sai Akhil V, Hema Lingireddy, Gowtham K V, Abhijeet Mudhale, Guru Sri B, Abhishek E
Publikováno v:
Environment Conservation Journal, Vol 25, Iss 1 (2024)
Providing food for the growing population is a challenging task, however, with historical agricultural practices, we can’t meet the food requirement of the world population. We are in the need to adopt modern technology to overcome adverse climatic
Externí odkaz:
https://doaj.org/article/0b6c012c7f99495a81dab69ef2bf60ae
Autor:
Heidi M. Schmidt, Evan R. DeVallance, Sara E. Lewis, Katherine C. Wood, Gowtham K. Annarapu, Mara Carreño, Scott A. Hahn, Madison Seman, Brooke A. Maxwell, Emily A. Hileman, Julia Z. Xu, Murugesan Velayutham, Werner J. Geldenhuys, Dario A. Vitturi, Sruti Shiva, Eric E. Kelley, Adam C. Straub
Publikováno v:
Redox Biology, Vol 62, Iss , Pp 102636- (2023)
Xanthine oxidase (XO) catalyzes the catabolism of hypoxanthine to xanthine and xanthine to uric acid, generating oxidants as a byproduct. Importantly, XO activity is elevated in numerous hemolytic conditions including sickle cell disease (SCD); howev
Externí odkaz:
https://doaj.org/article/fc1d13f5ed7a4f76bf1f12017427f9c4
Autor:
Deepa Gautam, Jyotsna Kailashiya, Arundhati Tiwari, Rameshwar Nath Chaurasia, Gowtham K. Annarapu, Prasenjit Guchhait, Debabrata Dash
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Prion peptide (PrP) misfolds to infectious scrapie isoform, the β pleat-rich insoluble fibrils responsible for neurodegeneration and fatal conformational diseases in humans. The amino acid sequence 106–126 from prion proteins, PrP(106–126), is h
Externí odkaz:
https://doaj.org/article/15d2f60114c8413ca5a8442bc8416b9c
Autor:
Gowtham K. Annarapu, Deirdre Nolfi-Donegan, Michael Reynolds, Yinna Wang, Lauryn Kohut, Brian Zuckerbraun, Sruti Shiva
Publikováno v:
Redox Biology, Vol 48, Iss , Pp 102205- (2021)
Hemolysis, a pathological component of many diseases, is associated with thrombosis and vascular dysfunction. Hemolytic products, including cell-free hemoglobin and free heme directly activate platelets. However, the effect of hemolysis on platelet d
Externí odkaz:
https://doaj.org/article/1ac3a0543df0448badf33ec395f68488
Autor:
Amrita Ojha, Angika Bhasym, Sriparna Mukherjee, Gowtham K. Annarapu, Teena Bhakuni, Irshad Akbar, Tulika Seth, Naval K. Vikram, Sudhanshu Vrati, Anirban Basu, Sankar Bhattacharyya, Prasenjit Guchhait
Publikováno v:
EBioMedicine, Vol 39, Iss , Pp 332-347 (2019)
Background: Activated platelets release cytokines/proteins including CXCL4 (PF4), CCL5 and fibrinopeptides, which regulate infection of several pathogenic viruses such as HIV, H1N1 and HCV in human. Since platelet activation is the hallmark of Dengue
Externí odkaz:
https://doaj.org/article/2160851007864ce5b417ce20fe394447
Autor:
Amer, Ahmed, Bhuvaneshwara, Chirag, Addluri, Gowtham K., Shaik, Mohammed M., Bonde, Vedant, Müller, Philipp
Listeners use short interjections, so-called backchannels, to signify attention or express agreement. The automatic analysis of this behavior is of key importance for human conversation analysis and interactive conversational agents. Current state-of
Externí odkaz:
http://arxiv.org/abs/2306.01656
Autor:
Gowtham K Annarapu, Rashi Singhal, Avinash Gupta, Sheetal Chawla, Harish Batra, Tulika Seth, Prasenjit Guchhait
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167899 (2016)
Intravascular hemolysis increases the risk of thrombosis in hemolytic disorders. Our previous study showed that the binding of adult hemoglobin (HbA) to glycoprotein (GP) 1bα induced the activation of platelets. The elevated plasma Hb or platelet su
Externí odkaz:
https://doaj.org/article/7e22761496874f4fa3425753b34c7168
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0154276 (2016)
Reports including our own describe that intravascular hemolysis increases the risk of thrombosis in hemolytic disorders. Our recent study shows that plasma Hb concentrations correlate directly with platelet activation in patients with paroxysmal noct
Externí odkaz:
https://doaj.org/article/49e4de4f1aad4a14b82e1ea1693ad23a
Autor:
Rashi Singhal, Gowtham K. Annarapu, Ankita Pandey, Sheetal Chawla, Amrita Ojha, Avinash Gupta, Miguel A. Cruz, Tulika Seth, Prasenjit Guchhait
Publikováno v:
Haematologica, Vol 100, Iss 12 (2015)
Intravascular hemolysis increases the risk of hypercoagulation and thrombosis in hemolytic disorders. Our study shows a novel mechanism by which extracellular hemoglobin directly affects platelet activation. The binding of Hb to glycoprotein1bα acti
Externí odkaz:
https://doaj.org/article/f6b0f74a61304c0d8fd2037e84e424d5
Autor:
Andraska, Elizabeth A., Denorme, Frederik, Kaltenmeier, Christof, Arivudainabi, Aishwarrya, Mihalko, Emily P., Dyer, Mitchell, Annarapu, Gowtham K., Zarisfi, Mohammadreza, Loughran, Patricia, Ozel, Mehves, Williamson, Kelly, Mota-Alvidrez, Roberto, Thomas, Kimberly, Shiva, Sruti, Shea, Susan, Steinman, Richard A., Campbell, Robert A., Rosengart, Matthew R., Neal, Matthew D.
Publikováno v:
In Journal of Thrombosis and Haemostasis August 2024