Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gowri, Kalugotla"'
Autor:
Forrest C Walker, Ebrahim Hassan, Stefan T Peterson, Rachel Rodgers, Lawrence A Schriefer, Cassandra E Thompson, Yuhao Li, Gowri Kalugotla, Carla Blum-Johnston, Dylan Lawrence, Broc T McCune, Vincent R Graziano, Larissa Lushniak, Sanghyun Lee, Alexa N Roth, Stephanie M Karst, Timothy J Nice, Jonathan J Miner, Craig B Wilen, Megan T Baldridge
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009402 (2021)
Interferons (IFNs) are key controllers of viral replication, with intact IFN responses suppressing virus growth and spread. Using the murine norovirus (MNoV) system, we show that IFNs exert selective pressure to limit the pathogenic evolutionary pote
Externí odkaz:
https://doaj.org/article/90fb07bf8a2e40fb883cfc49c1867b66
Autor:
Sabine Daemen, Anastasiia Gainullina, Gowri Kalugotla, Li He, Mandy M. Chan, Joseph W. Beals, Kim H. Liss, Samuel Klein, Ariel E. Feldstein, Brian N. Finck, Maxim N. Artyomov, Joel D. Schilling
Publikováno v:
Cell Reports, Vol 34, Iss 2, Pp 108626- (2021)
Summary: Macrophage-mediated inflammation is critical in the pathogenesis of non-alcoholic steatohepatitis (NASH). Here, we describe that, with high-fat, high-sucrose-diet feeding, mature TIM4pos Kupffer cells (KCs) decrease in number, while monocyte
Externí odkaz:
https://doaj.org/article/2d415d29b48b4ca78ceb4721531288bc
Autor:
Gowri Kalugotla, Harshad Ingle, Belgacem Mihi, Megan T. Baldridge, Misty Good, Michael S. Diamond, Rodney D. Newberry, Keely G. McDonald, Yuhao Li, Pritesh Desai, Sanghyun Lee, Ebrahim Hassan, Jana Gawron, Elizabeth A. Kennedy, Heyde Makimaa
Publikováno v:
Mucosal immunology
Although they globally cause viral gastroenteritis in children, astroviruses are understudied due to the lack of well-defined animal models. While murine astroviruses (muAstVs) chronically infect immunodeficient mice, a culture system and understandi
Autor:
Sanghyun, Lee, Gowri, Kalugotla, Harshad, Ingle, Rachel, Rodgers, Chunyan, Wu, Yating, Wang, Yuhao, Li, Xia, Yang, Jin, Zhang, Nicolette R, Borella, Hongju, Deng, Lindsay, Droit, Ryan, Hill, Stefan T, Peterson, Chandni, Desai, Dylan, Lawrence, Qun, Lu, Megan T, Baldridge
Publikováno v:
Autophagy. 18(5)
Mutations in the macroautophagy/autophagy gene
Autor:
Gowri Kalugotla, Sanghyun Lee, Lawrence Schriefer, Luis Alberto Casorla Perez, Huiyan Huang, Qun Lu, Anthony Orvedahl, Gary Silverman, Stephen Pak, David Wang, Megan T Baldridge
Publikováno v:
The Journal of Immunology. 208:114.13-114.13
Mutations in the autophagy gene EPG5 are responsible for Vici syndrome, a multisystem human genetic disease with a combined immunodeficiency component. However, the mechanism(s) by which EPG5 regulates immune signaling are incompletely understood. Pr
Autor:
Madeline Sauer, Eric Tycksen, Li He, Babak Razani, Joel D. Schilling, Gowri Kalugotla, Kassandra J. Weber
Publikováno v:
The Journal of Immunology. 201:2054-2069
Obesity and diabetes modulate macrophage activation, often leading to prolonged inflammation and dysfunctional tissue repair. Increasing evidence suggests that the NLRP3 inflammasome plays an important role in obesity-associated inflammation. We have
Autor:
Rachel Rodgers, Harshad Ingle, Gowri Kalugotla, Xia Yang, Qun Lu, Chandni Desai, Sanghyun Lee, Nicolette R. Borella, Lindsay Droit, Ryan Hill, Megan T. Baldridge, Stefan T. Peterson, Chunyan Wu, Yuhao Li, Hongju Deng, Dylan Lawrence, Ya-Ting Wang, Jin Zhang
Mutations in the macroautophagy/autophagy gene EPG5 are responsible for Vici syndrome, a human genetic disease characterized by combined immunodeficiency. Previously, we found that epg5−/- mice exhibit hyperinflammation in the lungs mediated by IL1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b7003222bb447a5961904bad5671c8d
Autor:
Alexa N. Roth, Lawrence A. Schriefer, Cassandra E Thompson, Rachel Rodgers, Megan T. Baldridge, Jonathan J. Miner, Yuhao Li, Ebrahim Hassan, Stephanie M. Karst, Forrest C. Walker, Dylan Lawrence, Carla Blum-Johnston, Sanghyun Lee, Vincent R. Graziano, Broc T. McCune, Gowri Kalugotla, Larissa Lushniak, Stefan T. Peterson, Craig B. Wilen, Timothy J. Nice
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 3, p e1009402 (2021)
PLoS Pathogens, Vol 17, Iss 3, p e1009402 (2021)
Interferons (IFNs) are key controllers of viral replication, with intact IFN responses suppressing virus growth and spread. Using the murine norovirus (MNoV) system, we show that IFNs exert selective pressure to limit the pathogenic evolutionary pote
Autor:
Abigail Reller, Joel D. Schilling, Gowri Kalugotla, Babak Razani, Li He, Kassandra J. Weber, Sabine Daemen
Obesity and diabetes are associated with macrophage dysfunction and increased NLRP3 inflammasome activation. Saturated fatty acids (FAs) are abundant in these metabolic disorders and have been associated with lysosome dysfunction and inflammasome act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d348ae607262d7ea6cf89cdfde8e8cd1
https://europepmc.org/articles/PMC7039344/
https://europepmc.org/articles/PMC7039344/
Autor:
Gowri Kalugotla, Anastasiia Gainullina, Joseph W. Beals, Kim H.H. Liss, Mandy M. Chan, Li He, Maxim N. Artyomov, Sabine Daemen, Ariel E. Feldstein, Joel D. Schilling, Samuel Klein, Brian N. Finck
Publikováno v:
Cell Reports, Vol 34, Iss 2, Pp 108626-(2021)
Cell reports
Cell reports
Summary: Macrophage-mediated inflammation is critical in the pathogenesis of non-alcoholic steatohepatitis (NASH). Here, we describe that, with high-fat, high-sucrose-diet feeding, mature TIM4pos Kupffer cells (KCs) decrease in number, while monocyte