Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Gowramma Byran"'
Autor:
Kalirajan Rajagopal, Anandarajagopal Kalusalingam, Anubhav Raj Bharathidasan, Aadarsh Sivaprakash, Krutheesh Shanmugam, Monall Sundaramoorthy, Gowramma Byran
Publikováno v:
Molecules, Vol 28, Iss 10, p 4175 (2023)
Cancer is a condition marked by abnormal cell proliferation that has the potential to invade or indicate other health issues. Human beings are affected by more than 100 different types of cancer. Some cancer promotes rapid cell proliferation, whereas
Externí odkaz:
https://doaj.org/article/492737bf97584ce8bb08efc1162df551
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 6, Iss 1, Pp 1-10 (2020)
Abstract Background In early 2020, many scientists are rushing to discover novel drugs and vaccines against the coronavirus, and treatments for COVID-19, because coronavirus disease 2019 (COVID-19), a life-threatening viral disease, affected first in
Externí odkaz:
https://doaj.org/article/9cc991ace9a5444ca3505e9137faae06
Autor:
Potlapati Varakumar, Kalirajan Rajagopal, Baliwada Aparna, Kannan Raman, Gowramma Byran, Clara Mariana Gonçalves Lima, Salma Rashid, Mohammed H. Nafady, Talha Bin Emran, Sławomir Wybraniec
Publikováno v:
Molecules, Vol 28, Iss 1, p 193 (2022)
This review summarized the current breakthroughs in the chemistry of acridines as anti-cancer agents, including new structural and biologically active acridine attributes. Acridine derivatives are a class of compounds that are being extensively resea
Externí odkaz:
https://doaj.org/article/6878b1de2c624a45b0847b8c6a6b16dd
Publikováno v:
Journal of Biomolecular Structure & Dynamics; 2024, Vol. 42 Issue 20, p10824-10834, 11p
Akademický článek
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Publikováno v:
Mini-Reviews in Medicinal Chemistry. 22:2769-2798
Abstract: Acridine derivatives have been thoroughly investigated and discovered to have multitarget qualities, inhibiting topoisomerase enzymes that regulate topological changes in DNA and interfering with DNA's vital biological function. This articl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9097498bd57d1541cec763ce16df4950
https://doi.org/10.2174/1389557522666220511125744
https://doi.org/10.2174/1389557522666220511125744
Publikováno v:
Applied Biochemistry and Biotechnology. 195:1014-1041
The clinically used glitazones (rosiglitazone and pioglitazone) for type 2 diabetes mellitus therapy have been linked to serious side effects such as fluid retention, congestive heart failure, weight gain, bone loss, and an increased risk of bladder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca1795aa0e029920d357f4c821db3bc8
https://doi.org/10.1007/s12010-022-04190-2
https://doi.org/10.1007/s12010-022-04190-2
Autor:
Gowramma Byran, Pulla Prudvi Raj, Kaviarasan Lakshmanan, Kalirajan Rajagopal, Praveen Thaggikuppe Krishnamurthy, Divya Jyothi Palati
Publikováno v:
Current Enzyme Inhibition. 18:92-104
Abstract: Poly [ADP-ribose] polymerase-1 [PARP-1] is a chromatin-bound nuclear enzyme that gets activated by DNA damage. It facilitates DNA repair by binding to DNA breaks and attracting DNA repair proteins to the site of damage. Increased PARP-1 exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac665a8a8ed4c030284747bfad7ebea2
https://doi.org/10.2174/1573408018666220321115033
https://doi.org/10.2174/1573408018666220321115033
Autor:
Gomathy Subramanian, Farhath Sherin, Naina Merin Joy, Ashish D Wadhwan, Gowramma Byran, A Shanish Antony
Publikováno v:
Rasayan Journal of Chemistry. 15:483-496
Seven protein families known as class III histone deacetylase for their characteristic features have been reported in mammals. Sirtuin3 (SIRT3) has gained considerable attention among the sirtuin members for its role in neurodegenerative disease. A n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b7e4ece14f4e61ab217f9f99832eba0
https://doi.org/10.31788/rjc.2022.1516628
https://doi.org/10.31788/rjc.2022.1516628
Autor:
Kantabathina Hemanth, Kaviarasan Lakshmanan, Kalirajan Rajagopal, null Piyongsola, Gowramma Byran
Publikováno v:
RASAYAN Journal of Chemistry. 15:1573-1587
Thiadiazole is a heterocyclic molecule made up of one sulphur atom, two nitrogen atoms, and two double-bonded 5- membered ring systems. Heterocyclic compounds having biological activity serve a significant role in medicinal chemistry. More than one o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c4e43edd3babd0202322ae7d4df79bd
https://doi.org/10.31788/rjc.2022.1516443
https://doi.org/10.31788/rjc.2022.1516443