Rosuvastatin / calcium carbonate co-precipitated nanoparticles: A novel synergistic approach enhancing local bone regeneration in osteoporotic rat model.

Autor: El-Salamouni NS; Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Pharos University in Alexandria, Canal El Mahmoudia Street, beside Green Plaza Complex 21648, Alexandria, Egypt. Electronic address: noha.soliman@pua.edu.eg., Gowayed MA; Department of Pharmacology & Therapeutics, Faculty of Pharmacy, Pharos University in Alexandria, Canal El Mahmoudia Street, beside Green Plaza Complex 21648, Alexandria, Egypt. Electronic address: mennatallah.gowayed@pua.edu.eg., El Achy S; Department of Pathology, Faculty of Medicine, Alexandria University, Alexandria, Egypt., El Shahawy M; Department of Oral Biology, Faculty of Dentistry, Minia University, Minia 51161, Egypt; Department of Oral Biology, Faculty of Dentistry, Kafrelsheikh University, Elgiesh street, Kafrelsheikh 33516, Egypt. Electronic address: samar.elachy@alexmed.edu.eg., Ghareeb DA; Bio-Screening and Preclinical Trial Lab, Biochemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt; Center of Excellence for Drug Preclinical Studies (CE-DPS), Pharmaceutical and Fermentation Industry Development Center, City of Scientific Research & Technological Applications (SRTA-city), New Borg El Arab, Alexandria, Egypt; Research Projects unit, Pharos University in Alexandria, Canal El Mahmoudia Street, beside Green Plaza Complex 21648, Alexandria, Egypt. Electronic address: d.ghareeb@alexu.edu.eg., Abdulmalek SA; Bio-Screening and Preclinical Trial Lab, Biochemistry Department, Faculty of Science, Alexandria University, Alexandria, Egypt. Electronic address: Shaymaa.abdulmalek@alexu.edu.eg., Kassem AA; Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Pharos University in Alexandria, Canal El Mahmoudia Street, beside Green Plaza Complex 21648, Alexandria, Egypt. Electronic address: jilabib@gmail.com., Labib GS; Faculty of Pharmacy, Alamein International University, Alamein 51718, Matrouh, Egypt. Electronic address: glabib@aiu.edu.eg.

Publikováno v: International journal of pharmaceutics [Int J Pharm] 2024 Nov 21, pp. 124977. Date of Electronic Publication: 2024 Nov 21.

Morin suppresses mTORc1/IRE-1α/JNK and IP3R-VDAC-1 pathways: Crucial mechanisms in apoptosis and mitophagy inhibition in experimental Huntington's disease, supported by in silico molecular docking simulations.

Autor: El-Emam MA; Department of Pharmacology and Therapeutics, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt., Sheta E; Department of Pathology, Faculty of Medicine, Alexandria University, Alexandria, Egypt., El-Abhar HS; Department of Pharmacology, Toxicology and Biochemistry, Faculty of Pharmacy, Future University in Egypt, Cairo, Egypt., Abdallah DM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt. Electronic address: dalaal.abdallah@pharma.cu.edu.eg., El Kerdawy AM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt; School of Pharmacy, College of Health and Science, University of Lincoln, Joseph Banks Laboratories, Green Lane, Lincoln, United Kingdom., Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt; School of Biotechnology, Badr University in Cairo, Badr City, Cairo, Egypt., Gowayed MA; Department of Pharmacology and Therapeutics, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt.

Publikováno v: Life sciences [Life Sci] 2024 Feb 01; Vol. 338, pp. 122362. Date of Electronic Publication: 2023 Dec 21.

Hyaluronic acid/diminazene aceturate combination ameliorates osteoarthritic anomalies in a rodent model: a role of the ACE2/Ang1-7/MasR axis.

Autor: Habib YH; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt., Sheta E; Department of Pathology, Faculty of Medicine, Alexandria University, Alexandria, Egypt., Khattab M; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt., Gowayed MA; Department of Pharmacology and Therapeutics, Faculty of Pharmacy, Pharos University in Alexandria, Canal El-Mahmoudia Str., Smouha Alexandria, Egypt. mennatallah.gowayed@pua.edu.eg.

Publikováno v: Inflammopharmacology [Inflammopharmacology] 2023 Dec; Vol. 31 (6), pp. 3263-3279. Date of Electronic Publication: 2023 Sep 19.

Propolis-loaded nanostructured lipid carriers halt breast cancer progression through miRNA-223 related pathways: an in-vitro/in-vivo experiment.

Autor: Shaker SA; Department of Biochemistry, Medical Research Institute, Alexandria University, Alexandria, Egypt., Alshufta SM; Department of Clinical Pathology, Faculty of Medicine, Aden University, Aden, Yemen., Gowayed MA; Department of Pharmacology and Therapeutics, Faculty of Pharmacy, Pharos University in Alexandria, Canal El-Mahmoudia Str., Smouha, Alexandria, Egypt. mennatallah.gowayed@pua.edu.eg., El-Salamouni NS; Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt., Bassam SM; Department of Pharmacognosy and Natural Products, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt., Megahed MA; Department of Biochemistry, Medical Research Institute, Alexandria University, Alexandria, Egypt., El-Tahan RA; Department of Biochemistry, Medical Research Institute, Alexandria University, Alexandria, Egypt.

Publikováno v: Scientific reports [Sci Rep] 2023 Sep 21; Vol. 13 (1), pp. 15752. Date of Electronic Publication: 2023 Sep 21.

The antidiabetic effect of superparamagnetic iron oxide nanoparticles highlights the role of WNT/AMPK/mTOR/FOXO1/mitochondrial DNA in muscle and kidney.

Autor: Gowayed MA; Department of Pharmacology & Therapeutics, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, 21311, Egypt., Ma Ali L; IBMM, Université Montpellier, CNRS, ENSCM, Montpellier, 34000, France.; Department of Biochemistry, Medical Research Institute, Alexandria University, Alexandria, 165, Egypt., Kamel MA; Department of Biochemistry, Medical Research Institute, Alexandria University, Alexandria, 165, Egypt., Oriquat GA; Department of Medical Laboratory Sciences, Faculty of Allied Medical Sciences, Al-Ahliyya Amman University, Amman, 19328, Jordan., Piñol R; Instituto de Nanociencia y Materiales de Aragón (INMA), CSIC-Universidad de Zaragoza, Zaragoza, 50009, Spain.; Departamento de Física de la Materia Condensada, Universidad de Zaragoza, Zaragoza, 50009, Spain., Millán A; Instituto de Nanociencia y Materiales de Aragón (INMA), CSIC-Universidad de Zaragoza, Zaragoza, 50009, Spain.; Departamento de Física de la Materia Condensada, Universidad de Zaragoza, Zaragoza, 50009, Spain., El-Tahan RA; Department of Biochemistry, Medical Research Institute, Alexandria University, Alexandria, 165, Egypt.

Publikováno v: Nanomedicine (London, England) [Nanomedicine (Lond)] 2023 Feb; Vol. 18 (5), pp. 417-435. Date of Electronic Publication: 2023 May 11.