Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Govind V. Kaigala"'
Autor:
Anna Fomitcheva-Khartchenko, Maria Anna Rapsomaniki, Bettina Sobottka, Peter Schraml, Govind V. Kaigala
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
A new workflow for protein-based tumor heterogeneity probing in tissues is here presented. Tumor heterogeneity is believed to be key for therapy failure and differences in prognosis in cancer patients. Comprehending tumor heterogeneity, especially at
Externí odkaz:
https://doaj.org/article/c5e6f35250e14d7eb9904b8e02f65774
Publikováno v:
The Analyst. 147:2040-2047
We propose microfluidic add-ons that can be easily added onto standard assay labware such as microwells and slides to enhance the kinetics of immunoassays. We design these monolithic devices having structures that leverage the pipetting step to deliv
Autor:
Prerit Mathur, Anna Fomitcheva Khartchenko, Stavros Stavrakis, Govind V. Kaigala, Andrew J. deMello
Publikováno v:
Analytical Chemistry, 94 (31)
We present a method for monitoring spatially localized antigen–antibody binding events on physiologically relevant substrates (cell and tissue sections) using fluorescence lifetime imaging. Specifically, we use the difference between the fluorescen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23cc9d6a6c15b12905339dcb9af3f5b7
https://hdl.handle.net/20.500.11850/569905
https://hdl.handle.net/20.500.11850/569905
Autor:
Federico Paratore, Baruch Rofman, Moran Bercovici, Vesna Bacheva, Maya Dolev, Govind V. Kaigala
Publikováno v:
Analytical chemistry. 94(30)
We present a microfluidic device for selective separation and extraction of molecules based on their diffusivity. The separation relies on electroosmotically-driven bidirectional flows in which high diffusivity species experience a net-zero velocity,
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176691 (2017)
We present a new concept, termed tissue lithography (TL), and its implementation which enables retrospective studies on formalin-fixed paraffin-embedded tissue sections. Tissue lithography uses a microfluidic probe to remove microscale areas of the p
Externí odkaz:
https://doaj.org/article/84c1d580a439444fb30a798341a740af
Publikováno v:
Trends in cancer. 8(12)
Tumor cells present complex behaviors in their interactions with other cells. This intricate behavior is driving the need to develop new tools to understand these ecosystems. The surge of spatial technologies allows evaluation of the complexity of re
Surface assays such as ELISA are pervasive in clinics and research and predominantly standardized in microtiter plates (MTP). MTPs provide many advantages but are often detrimental to surface assay efficiency due to inherent mass transport limitation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d1fb3403d4ca417eef3bc73303234e
Publikováno v:
Angewandte Chemie. 132:12994-12999
We present a new concept for on-chip separation that leverages bidirectional flow, to tune the dispersion regime of molecules and particles. The system can be configured so that low diffusivity species experience a ballistic transport regime and are
Autor:
Orcun Goksel, Nuri Murat Arar, Anna Fomitcheva Khartchenko, Pushpak Pati, Govind V. Kaigala, Aditya Kashyap, Maria Gabrani
Publikováno v:
IEEE Transactions on Biomedical Engineering, 66 (10)
IEEE Transactions on Biomedical Engineering, 66 (10)
ISSN:0018-9294
ISSN:1558-2531
ISSN:0018-9294
ISSN:1558-2531
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 37(32)
Patterning biomolecules on surfaces provides numerous opportunities for miniaturizing biological assays; biosensing; studying proteins, cells, and tissue sections; and engineering surfaces that include biological components. In this Feature Article,