Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Govert Hoogland"'
Autor:
Niels Knippenberg, Matthias Bauwens, Olaf Schijns, Govert Hoogland, Alexandru Florea, Kim Rijkers, Thomas J. Cleij, Kasper Eersels, Bart van Grinsven, Hanne Diliën
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-21 (2023)
Abstract By clearing GABA from the synaptic cleft, GABA transporters (GATs) play an essential role in inhibitory neurotransmission. Consequently, in vivo visualization of GATs can be a valuable diagnostic tool and biomarker for various psychiatric an
Externí odkaz:
https://doaj.org/article/b64430080ced41669b512618149e6f45
Autor:
Sander van Kuijk, Ghislaine A P G van Mastrigt, Govert Hoogland, Kim Rijkers, Jim Dings, Sandra M A van der Salm, Ilse E C W van Straaten, Julia T F Kellenaers, Olaf E M G Schijns, Marielle C G Vlooswijk, Louis G L Wagner, Sander Idema, Marian H J M Majoie
Publikováno v:
BMJ Open, Vol 13, Iss 7 (2023)
Introduction Resective epilepsy surgery is often seen as a last resort when treating drug-resistant epilepsy. Positive results on quality of life (QoL) and economic benefits after surgery argue for a less restrictive attitude towards epilepsy surgery
Externí odkaz:
https://doaj.org/article/78c582513195490d990483043d7a83a0
Autor:
Michel H. Y. Hu, Jean-Philippe Frimat, Kim Rijkers, Olaf E. M. G. Schijns, Arn M. J. M. van den Maagdenberg, Jim T. A. Dings, Regina Luttge, Govert Hoogland
Publikováno v:
Applied Sciences, Vol 13, Iss 3, p 1432 (2023)
A growing societal awareness is calling upon scientists to reconsider the use of animals in research, which stimulates the development of translational in vitro models. The physiological and architectural interactions between different cell types wit
Externí odkaz:
https://doaj.org/article/326a75b1c75f40a1b234e2fd548a4c1e
Autor:
Hanna Schenck, Eliisa Netti, Onno Teernstra, Inger De Ridder, Jim Dings, Mika Niemelä, Yasin Temel, Govert Hoogland, Roel Haeren
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The glycocalyx is an important constituent of blood vessels located between the bloodstream and the endothelium. It plays a pivotal role in intercellular interactions in neuroinflammation, reduction of vascular oxidative stress, and provides a barrie
Externí odkaz:
https://doaj.org/article/27edff2751e34da0af24f76c002d7d82
Autor:
Judith M. Lionarons, Govert Hoogland, Rutger J. Slegers, Hellen Steinbusch, Sandra M. H. Claessen, Johan S. H. Vles
Publikováno v:
Life, Vol 11, Iss 11, p 1155 (2021)
Background: Gastrointestinal (GI) complaints are frequently noted in aging dystrophinopathy patients, yet their underlying molecular mechanisms are largely unknown. As dystrophin protein isoform 71 (Dp71) is particularly implicated in the development
Externí odkaz:
https://doaj.org/article/1c3819d046fa4aecaafbe6c47f2824c4
Autor:
Luqman Khan, Rick van Lanen, Govert Hoogland, Olaf Schijns, Kim Rijkers, Dimitrios Kapsokalyvas, Marc van Zandvoort, Roel Haeren
Publikováno v:
Applied Sciences, Vol 11, Iss 5, p 2404 (2021)
Despite extensive research, the exact pathomechanisms associated with epileptic seizure formation and propagation have not been elucidated completely. Two-photon imaging (2PI) is a fluorescence-based microscopy technique that, over the years, has bee
Externí odkaz:
https://doaj.org/article/56ee51c24d3a4bfc97ec1b5d60a4b204
Autor:
Angelisa Frasca, Marlien Aalbers, Federica Frigerio, Fabio Fiordaliso, Monica Salio, Marco Gobbi, Alfredo Cagnotto, Fabrizio Gardoni, Giorgio S. Battaglia, Govert Hoogland, Monica Di Luca, Annamaria Vezzani
Publikováno v:
Neurobiology of Disease, Vol 43, Iss 2, Pp 507-515 (2011)
Pharmacological blockade of NR2B-containing N-methyl-d-aspartate receptors (NMDARs) during epileptogenesis reduces neurodegeneration provoked in the rodent hippocampus by status epilepticus. The functional consequences of NMDAR activation are crucial
Externí odkaz:
https://doaj.org/article/3f0f40636e4a4358968774125fd03b17
Autor:
Jacobus F.A. Jansen, Evi M.P. Lemmens, Gustav J. Strijkers, Jeanine J. Prompers, Olaf E.M.G. Schijns, M. Eline Kooi, Emile A.M. Beuls, Klaas Nicolay, Walter H. Backes, Govert Hoogland
Publikováno v:
Neurobiology of Disease, Vol 32, Iss 2, Pp 293-301 (2008)
Experimental febrile seizures (FS) are known to promote hyperexcitability of the limbic system and increase the risk for eventual temporal lobe epilepsy (TLE). Early markers of accompanying microstructural and metabolic changes may be provided by in
Externí odkaz:
https://doaj.org/article/61969a4d672f4503b70ce86a811170ef
LIM and SH3 protein 1 (LASP1) differentiates malignant chordomas from less malignant chondrosarcomas
Autor:
Cas Vanderheijden, Thomas Vaessen, Youssef Yakkioui, Robert Riedl, Yasin Temel, Koos Hovinga, Govert Hoogland
Publikováno v:
Journal of Neuro-Oncology, 158(1), 81-88. Springer, Cham
Purpose Chordomas are malignant tumors that develop along the neuraxis between skull-base and sacrum. Chondrosarcomas show similarities with chordomas, yet show less malignant behavior. LIM and SH3 protein 1 (LASP1) is a cytoskeletal protein known to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::552a96cb857b0308bf4dab09f5927b33
https://cris.maastrichtuniversity.nl/en/publications/2d323ebb-a5fa-486d-b76d-b92557891f97
https://cris.maastrichtuniversity.nl/en/publications/2d323ebb-a5fa-486d-b76d-b92557891f97
Autor:
Youssef Yakkioui, Cas Vanderheijden, Koos Hovinga, Thomas Vaessen, Govert Hoogland, Yasin Temel
Publikováno v:
World Neurosurgery. 156:125-132
Purpose A chordoma is a slow-growing, invasive neoplasm in the neuraxis, thought to arise from notochordal cells. At 10-year follow-up, the average survival rate is 50%, though the interindividual prognosis varies substantially. Here, we aim to provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b57ddfb868f5e67799030da4b67d857
https://doi.org/10.1016/j.wneu.2021.09.027
https://doi.org/10.1016/j.wneu.2021.09.027