Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Goverdhan Surineni"'
Autor:
Xiaopeng Peng, Ziwen Yu, Goverdhan Surineni, Bulian Deng, Meizhu Zhang, Chuan Li, Zhiqiang Sun, Wanyi Pan, Yao Liu, Shenglan Liu, Bin Yu, Jianjun Chen
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
In this study, a novel series of histone deacetylases 6 (HDAC6) inhibitors containing polycyclic aromatic rings were discovered and evaluated for their pharmacological activities. The most potent compound 10c exhibited high HDAC6 inhibitory activity
Externí odkaz:
https://doaj.org/article/88ad33862024465eabf4c987c34fa3eb
Autor:
Chiranjibi Chhotaray, Shuai Wang, Yaoju Tan, Amjad Ali, Muhammad Shehroz, Cuiting Fang, Yang Liu, Zhili Lu, Xingshan Cai, H. M. Adnan Hameed, Md Mahmudul Islam, Goverdhan Surineni, Shouyong Tan, Jianxiong Liu, Tianyu Zhang
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 1, Pp 13-22 (2020)
Mycobacterium abscessus is a fast growing Mycobacterium species mainly causing skin and respiratory infections in human. M. abscessus is resistant to numerous drugs, which is a major challenge for the treatment. In this study, we have sequenced the g
Externí odkaz:
https://doaj.org/article/4af4c5e5d29744dca0678d6cd05de51f
Autor:
R. Gajendra Reddy, Goverdhan Surineni, Dwaipayan Bhattacharya, Sandeep Kumar Marvadi, Arpita Sagar, Arunasree M. Kalle, Arvind Kumar, Srinivas Kantevari, Sumana Chakravarty
Publikováno v:
ACS Omega, Vol 4, Iss 17, Pp 17279-17294 (2019)
Externí odkaz:
https://doaj.org/article/8776df72d7eb4de494462e78fc2e8c9f
Autor:
Jianxiong Liu, Xingshan Cai, Shuai Wang, Mahmudul Islam, Muhammad Shehroz, Tianyu Zhang, Goverdhan Surineni, H.M. Adnan Hameed, Yaoju Tan, Cuiting Fang, Amjad Ali, Shouyong Tan, Zhili Lu, Chiranjibi Chhotaray, Yang Liu
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 1, Pp 13-22 (2020)
Mycobacterium abscessus is a fast growing Mycobacterium species mainly causing skin and respiratory infections in human. M. abscessus is resistant to numerous drugs, which is a major challenge for the treatment. In this study, we have sequenced the g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89fbb9a0c0e05aab4c64defa06d8cae6
https://doi.org/10.1534/g3.119.400737
https://doi.org/10.1534/g3.119.400737
Autor:
Sumana Chakravarty, R. Gajendra Reddy, Arvind Kumar, Arunasree M. Kalle, Goverdhan Surineni, Arpita Sagar, Dwaipayan Bhattacharya, Sandeep Kumar Marvadi, Srinivas Kantevari
Publikováno v:
ACS Omega, Vol 4, Iss 17, Pp 17279-17294 (2019)
ACS Omega
ACS Omega
Small-molecule inhibitors of HDACs (HDACi) induce hyperacetylation of histone and nonhistone proteins and have emerged as potential therapeutic agents in most animal models tested. The established HDACi vorinostat and tubastatin-A alleviate neurodege
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa5c8626266a7416d57bb481de5f80e6
https://doaj.org/article/8776df72d7eb4de494462e78fc2e8c9f
https://doaj.org/article/8776df72d7eb4de494462e78fc2e8c9f
Autor:
Goverdhan Surineni, Yamin Gao, Mahmudul Islam, Zhiyong Liu, Chiranjibi Chhotaray, Tianyu Zhang, H.M. Adnan Hameed, Muzammal Hussain, Zhili Lu
Publikováno v:
MedChemComm. 10:49-60
Tuberculosis (TB) has become one of the most significant public health problems in recent years. Antibiotic therapy remains the mainstay of TB control strategies, but the increasing resistance of mycobacterial species has heightened alarm, requiring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f499af7f220371acca9b2c852a0d95d9
https://doi.org/10.1039/c8md00389k
https://doi.org/10.1039/c8md00389k
Autor:
Zean Zhao, Jin Liu, Peihua Kuang, Jian Luo, Goverdhan Surineni, Xiaolin Cen, Ting Wu, Ying Cao, Pingzheng Zhou, Jianxin Pang, Qun Zhang, Jianjun Chen
Publikováno v:
European Journal of Medicinal Chemistry. 229:114092
Verinurad (RDEA3170) is a selective URAT1 inhibitor under investigation for the treatment of gout and hyperuricemia. In an effort to further improve the pharmacodynamics/pharmacokinetics of verinurad and to increase the structural diversity, we desig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0857d676517939d66dc433579d024060
https://doi.org/10.1016/j.ejmech.2021.114092
https://doi.org/10.1016/j.ejmech.2021.114092
Autor:
Chiranjibi, Chhotaray, Shuai, Wang, Yaoju, Tan, Amjad, Ali, Muhammad, Shehroz, Cuiting, Fang, Yang, Liu, Zhili, Lu, Xingshan, Cai, H M Adnan, Hameed, Md Mahmudul, Islam, Goverdhan, Surineni, Shouyong, Tan, Jianxiong, Liu, Tianyu, Zhang
Publikováno v:
G3: Genes|Genomes|Genetics
Mycobacterium abscessus is a fast growing Mycobacterium species mainly causing skin and respiratory infections in human. M. abscessus is resistant to numerous drugs, which is a major challenge for the treatment. In this study, we have sequenced the g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::39e7302e8fd98d576ca5d9cee0e9d007
https://pubmed.ncbi.nlm.nih.gov/31719113
https://pubmed.ncbi.nlm.nih.gov/31719113
Autor:
B. Sridhar, Sandeep Kumar Marvadi, Dharmarajan Sriram, Goverdhan Surineni, Srinivas Kantevari, Rudraraju Srilakshmi Reshma, Vagolu Siva Krishna
Publikováno v:
Bioorganic chemistry. 96
We, herein, describe the synthesis of a series of novel aryl tethered 7,8-dihydroquinolin-5(6H)-ylidenehydrazinecarbothioamides 4a–v, which showed in vitro and in vivo antimycobacterial activity against Mycobacterium tuberculosis (Mtb) H37Rv. The i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a48e0a4265a67b37e97085531387ea
https://pubmed.ncbi.nlm.nih.gov/32007719
https://pubmed.ncbi.nlm.nih.gov/32007719
Autor:
Yaoju Tan, Zhili Lu, Huofeng Jiang, Cuiting Fang, Yang Zhou, Muzammal Hussain, Shouyong Tan, Zhijun Yu, Jinsong Liu, Gaëlle Guiewi Makafe, Yunxiang Tang, Chiwala Gift, Goverdhan Surineni, Tianyu Zhang, Mugweru Julius, Jianxiong Liu, Zhiyong Liu, Qiang Zhu, Jiancun Zhang, Lanying Liu, Nai-Kei Wong
Publikováno v:
Cell chemical biology. 26(8)
There is a great need for identification and development of new anti-tuberculosis drugs with novel targets. Recent drug-discovery efforts typically focus on identifying inhibitors but not activators that perturb metabolic enzymes' functions as a mean
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2cad0466f593003a971c9a1769a58ce
https://pubmed.ncbi.nlm.nih.gov/31204286
https://pubmed.ncbi.nlm.nih.gov/31204286