Structures of the Foamy virus fusion protein reveal an unexpected link with the F protein of paramyxo- and pneumoviruses.

Autor: Fernández I; Institut Pasteur, Université Paris Cité, CNRS UMR3569, Unité de Virologie Structurale, 75015 Paris, France., Bontems F; Institut Pasteur, Université Paris Cité, CNRS UMR3569, Unité de Virologie Structurale, 75015 Paris, France.; Institut de Chimie des Substances Naturelles, CNRS UPR2301, Université Paris Saclay, 91190 Gif-sur-Yvette, France., Brun D; Institut Pasteur, Université Paris Cité, CNRS UMR3569, Unité de Virologie Structurale, 75015 Paris, France., Coquin Y; Institut Pasteur, Université Paris Cité, CNRS UMR3569, Unité d'Epidémiologie et Physiopathologie des Virus Oncogènes, 75015 Paris, France., Goverde CA; Institute of Bioengineering, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Correia BE; Institute of Bioengineering, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland., Gessain A; Institut Pasteur, Université Paris Cité, CNRS UMR3569, Unité d'Epidémiologie et Physiopathologie des Virus Oncogènes, 75015 Paris, France., Buseyne F; Institut Pasteur, Université Paris Cité, CNRS UMR3569, Unité d'Epidémiologie et Physiopathologie des Virus Oncogènes, 75015 Paris, France., Rey FA; Institut Pasteur, Université Paris Cité, CNRS UMR3569, Unité de Virologie Structurale, 75015 Paris, France., Backovic M; Institut Pasteur, Université Paris Cité, CNRS UMR3569, Unité de Virologie Structurale, 75015 Paris, France.

Publikováno v: Science advances [Sci Adv] 2024 Oct 11; Vol. 10 (41), pp. eado7035. Date of Electronic Publication: 2024 Oct 11.

Computational design of soluble and functional membrane protein analogues.

Autor: Goverde CA; Laboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland., Pacesa M; Laboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland., Goldbach N; Laboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland., Dornfeld LJ; Laboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland., Balbi PEM; Laboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland., Georgeon S; Laboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland., Rosset S; Laboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland., Kapoor S; Department of Structural Biology, University at Buffalo, Buffalo, NY, USA., Choudhury J; Department of Structural Biology, University at Buffalo, Buffalo, NY, USA., Dauparas J; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Schellhaas C; Laboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland., Kozlov S; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Baker D; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA., Ovchinnikov S; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA., Vecchio AJ; Department of Structural Biology, University at Buffalo, Buffalo, NY, USA., Correia BE; Laboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland. bruno.correia@epfl.ch.

Publikováno v: Nature [Nature] 2024 Jul; Vol. 631 (8020), pp. 449-458. Date of Electronic Publication: 2024 Jun 19.

An atlas of protein homo-oligomerization across domains of life.

Autor: Schweke H; Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot, Israel., Pacesa M; Laboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland., Levin T; Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot, Israel., Goverde CA; Laboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland., Kumar P; School of Chemistry, University of Bristol, Bristol BS8 1TS, UK; School of Biochemistry, University of Bristol, Bristol BS8 1TD, UK; Bristol BioDesign Institute, University of Bristol, Life Sciences Building, Bristol BS8 1TQ, UK; Max Planck-Bristol Centre for Minimal Biology, University of Bristol, Cantock's Close, Bristol BS8 1TS, UK., Duhoo Y; Protein Production and Structure Characterization Core Facility (PTPSP), School of Life Sciences, École polytechnique Fédérale de Lausanne, Lausanne, Switzerland., Dornfeld LJ; Laboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland., Dubreuil B; Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot, Israel., Georgeon S; Laboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland., Ovchinnikov S; John Harvard Distinguished Science Fellowship Program, Harvard University, Cambridge, MA, USA., Woolfson DN; School of Chemistry, University of Bristol, Bristol BS8 1TS, UK; School of Biochemistry, University of Bristol, Bristol BS8 1TD, UK; Bristol BioDesign Institute, University of Bristol, Life Sciences Building, Bristol BS8 1TQ, UK; Max Planck-Bristol Centre for Minimal Biology, University of Bristol, Cantock's Close, Bristol BS8 1TS, UK. Electronic address: d.n.woolfson@bristol.ac.uk., Correia BE; Laboratory of Protein Design and Immunoengineering, École Polytechnique Fédérale de Lausanne and Swiss Institute of Bioinformatics, Lausanne, Switzerland. Electronic address: bruno.correia@epfl.ch., Dey S; Department of Bioscience and Bioengineering, Indian Institute of Technology Jodhpur, Rajasthan, India. Electronic address: sdey@iitj.ac.in., Levy ED; Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot, Israel. Electronic address: emmanuel.levy@gmail.com.

Publikováno v: Cell [Cell] 2024 Feb 15; Vol. 187 (4), pp. 999-1010.e15. Date of Electronic Publication: 2024 Feb 06.