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pro vyhledávání: '"Govardhanan Nagaiah"'
Autor:
Govardhanan Nagaiah, Pavan Tenneti
Publikováno v:
Cureus
The prognosis of elderly patients with acute myeloid leukemia (AML) is poor. Intensive chemotherapy with the combination of cytarabine and anthracyclines is typically used as the first-line treatment in the elderly with newly diagnosed AML who are ab
Autor:
Afshin Dowlati, Govardhanan Nagaiah, Robert Chapman, Jay Wasman, Pierre Lavertu, Pingfu Fu, Panayiotis Savvides, Scot C. Remick, John J. Wright
Publikováno v:
Thyroid. 23:600-604
Anaplastic thyroid cancer (ATC) is a rare but highly aggressive malignancy with a median survival of 3-5 months. The BRAF oncogene is mutated to its active form in up to 24% of ATC cases. Sorafenib is a tyrosine kinase inhibitor that acts on the RAF-
Publikováno v:
Breast Cancer Management. 1:47-56
SUMMARY The majority of patients with breast cancer are estrogen- and progesterone-receptor positive, and have benefited from the development of anti-estrogen therapies, such as tamoxifen and aromatase inhibitors. Unfortunately, metastatic patients w
Autor:
Jame Abraham, Govardhanan Nagaiah
Publikováno v:
Advances in the Management of Triple Negative Breast Cancer. :16-23
Publikováno v:
Expert Review of Anticancer Therapy. 11:1277-1282
As mortality in breast cancer patients has improved, morbidity of treatment has become increasingly important. Cognitive dysfunction has been considered as a morbid condition that may possibly result from aromatase inhibitor therapy, the standard tre
Autor:
Scot C. Remick, Govardhanan Nagaiah
Publikováno v:
Future Oncology. 6:1219-1228
Combretastatin A4 phosphate (CA4P) is the lead compound of a relatively new class of agents termed vascular disrupting agents that target existing tumor blood vessels. Rapid tumor blood flow shutdown has been demonstrated in preclinical models and pa
Autor:
Govardhanan Nagaiah, Jame Abraham
Publikováno v:
Clinical Breast Cancer. 10:209-216
Most deaths from breast cancer are from metastatic disease. Tests that predict an individual's risk of developing metastatic disease could be useful. There is growing evidence that circulating tumor cells (CTC) could help predict recurrence and effec
Autor:
Nathan A. Berger, Kathryn E. Engelhardt, Tanyanika Phillips Towe, Govardhanan Nagaiah, Elizabeth E. O'Toole
Publikováno v:
Journal of the American Geriatrics Society. 57:s253-s258
Healthcare practice for cancer care is rapidly evolving because of advances in technology, scientific discovery, drug development, and aging demographics in America. Among the substantive changes in science and drug development is targeted therapy. T
Publikováno v:
Clinical advances in hematologyoncology : HO. 10(9)
Autor:
Govardhanan Nagaiah, Colin J. Mooney, Scot C. Remick, James Parmentier, Akm Mosharraf Hossain
Publikováno v:
Journal of Oncology
Journal of Oncology, Vol 2011 (2011)
Journal of Oncology, Vol 2011 (2011)
Anaplastic thyroid cancer (ATC) is an uncommon malignancy of the thyroid. Only 1-2% of thyroid cancers are anaplastic, but the disease contributes to 14–50% of the mortality with a median survival of 3 to 5 months. Most patients diagnosed with this