335 Cryogenic electron microscopy studies of human CFTR folding and conformational dynamics elucidate a novel potentiator binding site in the nucleotide binding domains that supports an alternative channelgating mechanism

Autor: Wang, C., Yang, Z., Aleksandrov, A., Vorobiev, S., Loughlin, B., Rich, Z., Clarke, O., Jiang, F., Brouillette, C., Urbatsch, I., Frank, J., Lukacs, G., Govaerts, C., Kappes, J., Hunt, J.

Publikováno v: In Journal of Cystic Fibrosis October 2023 22 Supplement 3:S167-S167

SESSION 4: GPCRs AND TRANSPORTERS: LIGANDS, COFACTORS, DRUG DEVELOPMENT.

Autor: VON HEIJNE, GUNNAR, GOVAERTS, C.¹, PARMENTIER, M.²

Publikováno v: New Chemistry & New Opportunities From the Expanding Protein Universe - Proceedings of the 23rd International Solvay Conference on Chemistry. 2014, p203-227. 25p.

Hyphenation of liquid chromatography to ion trap mass spectrometry to identify minor components in polypeptide antibiotics.

Autor: Govaerts, C.¹, Adams, E.¹, Van Schepdael, Ann¹ ann.vanschepdael@pharm.kuleuven.ac.be, Hoogmartens, J.¹

Publikováno v: Analytical & Bioanalytical Chemistry. Nov2003, Vol. 377 Issue 5, p909-921. 13p.

Evidence for assembly of prions with left-handed beta-helices into trimers

Autor: Govaerts, C, Wille, H, Prusiner, S B, Cohen, F E

Publikováno v: Govaerts, C; Wille, H; Prusiner, S B; & Cohen, F E. (2004). Evidence for assembly of prions with left-handed beta-helices into trimers. Proceedings of the National Academy of Sciences of the United States of America, 101(22), 8342-8347. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/56h2p2xf

Studies using low-resolution fiber diffraction, electron microscopy, and atomic force microscopy on various amyloid fibrils indicate that the misfolded conformers must be modular, compact, and adopt a cross-beta structure. In an earlier study, we use

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::0d032faa4defcecd43195c632f6b4903
http://www.escholarship.org/uc/item/56h2p2xf

Evidences for an allelic variant of the human LC/CG receptor rather than a gene duplication: functional comparison of wild-type and variant receptors

Autor: Rodien, P, Cetani, F, Costagliola, S, Tonacchera, Massimo, Duprez, L, Minegishi, T, Govaerts, C, Vassart, G.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3728::d11cd267d5a4db7ddbcd08e61911110a
http://hdl.handle.net/11568/49283