Genetics of Latin American Diversity Project: Insights into population genetics and association studies in admixed groups in the Americas.

Autor: Borda V; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA; University of Maryland Institute for Health Computing, University of Maryland School of Medicine, North Bethesda, MD 20852, USA. Electronic address: vicbp1@gmail.com., Loesch DP; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Guo B; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Laboulaye R; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Veliz-Otani D; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA., French JN; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Leal TP; Lerner Research Institute, Genomic Medicine, Cleveland Clinic, Cleveland, OH, USA., Gogarten SM; Department of Biostatistics, University of Washington, Seattle, WA, USA., Ikpe S; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Gouveia MH; Center for Research on Genomics and Global Health, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA., Mendes M; Department of Genetics, Ecology, and Evolution, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Abecasis GR; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Alvim I; Department of Genetics, Ecology, and Evolution, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Arboleda-Bustos CE; Neuroscience and Cell Death Research Groups, Medical School and Genetic Institute, Universidad Nacional de Colombia, Bogota, Colombia., Arboleda G; Neuroscience and Cell Death Research Groups, Medical School and Genetic Institute, Universidad Nacional de Colombia, Bogota, Colombia., Arboleda H; Neuroscience and Cell Death Research Groups, Medical School and Genetic Institute, Universidad Nacional de Colombia, Bogota, Colombia., Barreto ML; Instituto de Saúde Coletiva, Universidade Federal da Bahia, Salvador, BA 40110-040, Brazil., Barwick L; LTRC Data Coordinating Center, The Emmes Company, Rockville, MD, USA., Bezzera MA; Department of Genetics, Federal University of Pernambuco, Av. Prof. Moraes Rego, 1235, Recife, PE 50670-901, Brazil., Blangero J; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., Borges V; Movement Disorders Unit, Department of Neurology and Neurosurgery, Universidade Federal de São Paulo, São Paulo, Brazil., Caceres O; Instituto Nacional de Salud, Lima, Peru; Facultad de Ciencias de la Salud, Universidad Científica del Sur, Lima, Peru., Cai J; Department of Biostatistics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Chana-Cuevas P; CETRAM, Facultad de Ciencias Médicas, Universidad de Santiago de Chile, Santiago, Chile., Chen Z; Keck School of Medicine, University of Southern California, Los Angeles, Los Angeles, CA, USA., Custer B; Vitalant Research Institute, San Francisco, CA, USA., Dean M; Laboratory of Genomic Diversity, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD, USA., Dinardo C; Instituto de Medicina Tropical, University of São Paulo, São Paulo, Brazil., Domingos I; Department of Genetics, Federal University of Pernambuco, Av. Prof. Moraes Rego, 1235, Recife, PE 50670-901, Brazil., Duggirala R; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., Dieguez E; Neurology Institute, Universidad de la República, Montevideo, Uruguay., Fernandez W; Neuroscience and Cell Death Research Groups, Medical School and Genetic Institute, Universidad Nacional de Colombia, Bogota, Colombia., Ferraz HB; Movement Disorders Unit, Department of Neurology and Neurosurgery, Universidade Federal de São Paulo, São Paulo, Brazil., Gilliland F; Keck School of Medicine, University of Southern California, Los Angeles, Los Angeles, CA, USA., Guio H; Instituto Nacional de Salud, Lima, Peru; INBIOMEDIC Research Center, Lima, Peru; Universidad de Huánuco, Huánuco, Peru., Horta B; Faculdade de Medicina, Departamento de Medicina Social, Universidade Federal de Pelotas, Pelotas, RS, Brazil., Curran JE; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., Johnsen JM; Bloodworks Northwest Research Institute, Seattle, WA, USA., Kaplan RC; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Kelly S; Vitalant Research Institute, San Francisco, CA, USA; UCSF Benioff Children's Hospital, University of California, San Francisco, Oakland, CA, USA., Kenny EE; Icahn School of Medicine at Mount Sinai, New York, NY, USA., Konkle BA; Department of Medicine, University of Washington, Seattle, WA, USA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Lescano A; Neurology Institute, Universidad de la República, Montevideo, Uruguay., Lima-Costa MF; Instituto de Pesquisas René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, MG, Brazil., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Manichaikul A; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Meyers DA; Division of Genetics, Genomics, and Precision Medicine, University of Arizona, Tucson, AZ, USA., Naslavsky MS; Human Genome and Stem Cell Research Center, University of São Paulo, São Paulo, SP, Brazil., Nickerson DA; Department of Genome Sciences, University of Washington, Seattle, WA, USA., North KE; Department of Epidemiology, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Padilla C; Instituto Nacional de Salud, Lima, Peru., Preuss M; Icahn School of Medicine at Mount Sinai, New York, NY, USA., Raggio V; Genetics Department, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay., Reiner AP; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA; Department of Epidemiology, University of Washington, Seattle, WA, USA., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Rieder CR; Departamento de Neurologia, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil., Rienstra M; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA USA., Rundek T; Department of Neurology, Miller School of Medicine, and The Evelyn F. McKnight Brain Institute, University of Miami, Miami, FL, USA., Sacco RL; Department of Neurology, Miller School of Medicine, and The Evelyn F. McKnight Brain Institute, University of Miami, Miami, FL, USA., Sanchez C; Instituto Nacional de Salud, Lima, Peru., Sankaran VG; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Santos-Lobato BL; Instituto de Ciências da Saúde, Universidade Federal do Pará, Belém, Brazil., Schumacher-Schuh AF; Departamento de Farmacologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Serviço de Neurologia, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil., Scliar MO; Human Genome and Stem Cell Research Center, University of São Paulo, São Paulo, SP, Brazil., Silverman EK; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Sofer T; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Harvard Medical School, Boston, MA USA., Lasky-Su J; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Tumas V; Ribeirão Preto Medical School, Universidade de São Paulo, Ribeirão Preto, Brazil., Weiss ST; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Mata IF; University of Maryland Institute for Health Computing, University of Maryland School of Medicine, North Bethesda, MD 20852, USA., Hernandez RD; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA; Quantitative Biosciences Institute, University of California, San Francisco, San Francisco, CA, USA; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94143, USA., Tarazona-Santos E; Department of Genetics, Ecology, and Evolution, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; Facultad de Salud Pública y Administración. Universidad Peruana Cayetano Heredia, Lima, Peru., O'Connor TD; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA; Program in Health Equity and Population Health, University of Maryland School of Medicine, Baltimore, MD 21201, USA; Program in Personalized Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA. Electronic address: timothydoconnor@gmail.com.

Publikováno v: Cell genomics [Cell Genom] 2024 Nov 13; Vol. 4 (11), pp. 100692. Date of Electronic Publication: 2024 Oct 31.

Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas.

Autor: Hughes O; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK., Bentley AR; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Breeze CE; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department Health and Human Services, Bethesda, MD, USA; UCL Cancer Institute, University College London, London, UK., Aguet F; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Xu X; Division of Cardiovascular Sciences, Faculty of Biology, Medicine, and Health, The University of Manchester, Manchester, UK., Nadkarni G; The Charles Bronfman Institute of Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Sun Q; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Lin BM; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Gilliland T; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA; Program in Medical and Population Genetics and the Cardiovascular Disease Initiative, Broad Institute, Cambridge, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA., Meyer MC; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Du J; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Raffield LM; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Kramer H; Division of Nephrology and Hypertension, Loyola University Chicago, Maywood, IL, USA., Morton RW; Population Health Research Institute, Hamilton, ON, Canada; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada., Gouveia MH; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Atkinson EG; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Valladares-Salgado A; Unidad de Investigación Médica en Bioquímica, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico., Wacher-Rodarte N; Unidad de Investigación Médica en Epidemiologia Clinica, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico., Dueker ND; John P Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA USA., Hai Y; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA USA., Adeyemo A; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Best LG; Missouri Breaks Industries Research Inc., Eagle Butte, SD, USA., Cai J; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Chen G; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Chong M; Population Health Research Institute, Hamilton, ON, Canada; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada., Doumatey A; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Eales J; Division of Cardiovascular Sciences, Faculty of Biology, Medicine, and Health, The University of Manchester, Manchester, UK., Goodarzi MO; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Ipp E; Division of Endocrinology and Metabolism, Department of Medicine, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Irvin MR; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA., Jiang M; Department of Applied Physical Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Jones AC; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Krieger JE; Laboratório de Genética e Cardiologia Molecular do Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Lange EM; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Lanktree MB; Division of Nephrology, Department of Medicine, McMaster University, Hamilton, ON, Canada., Lash JP; Division of Nephrology, Department of Medicine, University of Illinois, Chicago, IL, USA., Lotufo PA; Center for Clinical and Epidemiological Research, Hospital Universitário, Universidade de São Paulo (USP), São Paulo, Brazil., Loos RJF; The Charles Bronfman Institute of Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Ha My VT; The Charles Bronfman Institute of Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Peralta-Romero J; Unidad de Investigación Médica en Bioquímica, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico., Qi L; Department of Public Health Sciences, School of Medicine, University of California Davis, Davis, CA, USA., Raffel LJ; Department of Pediatrics, Genetic and Genomic Medicine, University of California, Irvine, Irvine, CA, USA., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Rodriquez EJ; Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA., Tarazona-Santos E; Departamento de Genética, Ecologia e Evolução, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Taylor KD; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA USA., Umans JG; MedStar Health Research Institute, Hyattsville MD and Georgetown-Howard Universities Center for Clinical and Translational Science, Washington, DC, USA., Wen J; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Young BA; University of Washington School of Medicine, Seattle, WA, USA; Office of Healthcare Equity, UW Justice, Equity, Diversity, and Inclusion Center for Transformational Research (UW JEDI-CTR), University of Washington, Seattle, WA, USA; Division of Nephrology, Department of Medicine, University of Washington, Seattle, WA, USA; Kidney Research Institute, Department of Medicine, University of Washington, Seattle, WA, USA., Yu Z; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA; Program in Medical and Population Genetics and the Cardiovascular Disease Initiative, Broad Institute, Cambridge, MA, USA., Zhang Y; Center for American Indian Health Research, Department of Biostatistics and Epidemiology, Hudson College of Public Health, The University of Oklahoma Health Sciences Center, Oklahoma, OK, USA., Ida Chen YD; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA USA., Rundek T; Department of Neurology, Epidemiology and Public Health, Miller School of Medicine, University of Miami, Miami, FL, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA USA., Cruz M; Unidad de Investigación Médica en Bioquímica, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico., Fornage M; Brown Foundation Institute of Molecular Medicine, Houston, TX, USA., Lima-Costa MF; Instituto René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, Brazil., Pereira AC; Laboratório de Genética e Cardiologia Molecular do Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Aging Division, Brigham Women's Hospital, Department of Medicine, Harvard Medical School, Boston, MA, USA., Paré G; Population Health Research Institute, Hamilton, ON, Canada; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada., Natarajan P; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA; Program in Medical and Population Genetics and the Cardiovascular Disease Initiative, Broad Institute, Cambridge, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA., Cole SA; Texas Biomedical Research Institute, San Antonio, TX, USA., Carson AP; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Lange LA; Department of Biomedical Informatics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Li Y; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Perez-Stable EJ; National Institute on Minority Health and Health Disparities, National Institutes of Health, Bethesda, MD, USA., Do R; The Charles Bronfman Institute of Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Charchar FJ; School of Science, Psychology and Sport, Federation University, Ballarat, VIC, Australia; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK; Department of Physiology, University of Melbourne, Melbourne, VIC, Australia., Tomaszewski M; Division of Cardiovascular Sciences, Faculty of Biology, Medicine, and Health, The University of Manchester, Manchester, UK; Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Mychaleckyj JC; Department of Public Health Sciences, School of Medicine, University of California Davis, Davis, CA, USA., Rotimi C; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Morris AP; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK. Electronic address: andrew.morris-5@manchester.ac.uk., Franceschini N; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: noraf@unc.edu.

Publikováno v: Cell genomics [Cell Genom] 2024 Jan 10; Vol. 4 (1), pp. 100468. Date of Electronic Publication: 2023 Dec 22.

Sickle cell allele HBB-rs334(T) is associated with decreased risk of childhood Burkitt lymphoma in East Africa.

Autor: Hong HG; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland, USA., Gouveia MH; Center for Research on Genomics and Global Health, NHGRI, National Institutes of Health, Bethesda, Maryland, USA., Ogwang MD; EMBLEM Study, St. Mary's Hospital Lacor, Gulu, Uganda.; EMBLEM Study, African Field Epidemiology Network, Kampala, Uganda., Kerchan P; EMBLEM Study, African Field Epidemiology Network, Kampala, Uganda.; EMBLEM Study, Kuluva Hospital, Arua, Uganda., Reynolds SJ; Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA., Tenge CN; EMBLEM Study, Moi University College of Health Sciences, Eldoret, Kenya., Were PA; EMBLEM Study, Academic Model Providing Access To Healthcare (AMPATH), Eldoret, Kenya., Kuremu RT; EMBLEM Study, Moi University College of Health Sciences, Eldoret, Kenya., Wekesa WN; EMBLEM Study, Moi University College of Health Sciences, Eldoret, Kenya., Masalu N; EMBLEM Study, Bugando Medical Center, Mwanza, Tanzania., Kawira E; EMBLEM Study, Shirati Health, Education, and Development Foundation, Shirati, Tanzania., Kinyera T; EMBLEM Study, St. Mary's Hospital Lacor, Gulu, Uganda.; EMBLEM Study, African Field Epidemiology Network, Kampala, Uganda., Wang X; Sickle Cell Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA., Zhou J; Department of Statistics and Probability, Michigan State University, East Lansing, Michigan, USA., Leal TP; Lerner Research Institute, Genomic Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA., Otim I; EMBLEM Study, St. Mary's Hospital Lacor, Gulu, Uganda.; EMBLEM Study, African Field Epidemiology Network, Kampala, Uganda., Legason ID; EMBLEM Study, African Field Epidemiology Network, Kampala, Uganda.; EMBLEM Study, Kuluva Hospital, Arua, Uganda., Nabalende H; EMBLEM Study, St. Mary's Hospital Lacor, Gulu, Uganda.; EMBLEM Study, African Field Epidemiology Network, Kampala, Uganda., Dhudha H; EMBLEM Study, Bugando Medical Center, Mwanza, Tanzania., Mumia M; EMBLEM Study, Academic Model Providing Access To Healthcare (AMPATH), Eldoret, Kenya., Baker FS; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland, USA., Okusolubo T; Sickle Cell Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA., Ayers LW; Department of Pathology, The Ohio State University, Columbus, Ohio, USA., Bhatia K; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland, USA., Goedert JJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland, USA., Woo J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland, USA., Manning M; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA., Cole N; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA., Luo W; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA., Hicks B; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA., Chagaluka G; Departments of Pediatrics and Surgery, College of Medicine, University of Malawi, Blantyre, Malawi., Johnston WT; Epidemiology and Cancer Statistics Group, Department of Health Sciences, University of York, York, UK., Mutalima N; Epidemiology and Cancer Statistics Group, Department of Health Sciences, University of York, York, UK.; Cancer Epidemiology Unit, University of Oxford, Oxford, UK., Borgstein E; Departments of Pediatrics and Surgery, College of Medicine, University of Malawi, Blantyre, Malawi., Liomba GN; Departments of Pediatrics and Surgery, College of Medicine, University of Malawi, Blantyre, Malawi., Kamiza S; Departments of Pediatrics and Surgery, College of Medicine, University of Malawi, Blantyre, Malawi., Mkandawire N; Departments of Pediatrics and Surgery, College of Medicine, University of Malawi, Blantyre, Malawi., Mitambo C; Research Department, Ministry of Health, Lilongwe, Malawi., Molyneux EM; Departments of Pediatrics and Surgery, College of Medicine, University of Malawi, Blantyre, Malawi., Newton R; Epidemiology and Cancer Statistics Group, Department of Health Sciences, University of York, York, UK., Hutchinson A; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA., Yeager M; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA., Adeyemo AA; Center for Research on Genomics and Global Health, NHGRI, National Institutes of Health, Bethesda, Maryland, USA., Thein SL; Sickle Cell Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA., Rotimi CN; Center for Research on Genomics and Global Health, NHGRI, National Institutes of Health, Bethesda, Maryland, USA., Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland, USA., Prokunina-Olsson L; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland, USA., Mbulaiteye SM; Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland, USA.

Publikováno v: American journal of hematology [Am J Hematol] 2024 Jan; Vol. 99 (1), pp. 113-123. Date of Electronic Publication: 2023 Nov 27.

Random forest classifiers trained on simulated data enable accurate short read-based genotyping of structural variants in the alpha globin region at Chr16p13.3.

Autor: Hansen NF; Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA., Wang X; Sickle Cell Branch, National Heart, Lung and Blood Institute, NIH, Bethesda, MD 20892, USA., Tegegn MB; Sickle Cell Branch, National Heart, Lung and Blood Institute, NIH, Bethesda, MD 20892, USA., Liu Z; Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA., Gouveia MH; Center for Research on Genomics and Global Health, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA., Hill G; Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA., Lin JC; Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA., Okulosubo T; Sickle Cell Branch, National Heart, Lung and Blood Institute, NIH, Bethesda, MD 20892, USA., Shriner D; Center for Research on Genomics and Global Health, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA., Thein SL; Sickle Cell Branch, National Heart, Lung and Blood Institute, NIH, Bethesda, MD 20892, USA., Mullikin JC; Cancer Genetics and Comparative Genomics Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Nov 27. Date of Electronic Publication: 2023 Nov 27.

Universal genome-wide association studies: Powerful joint ancestry and association testing.

Autor: Shriner D; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD 20892, USA., Bentley AR; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD 20892, USA., Gouveia MH; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD 20892, USA., Heuston EF; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD 20892, USA., Doumatey AP; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD 20892, USA., Chen G; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD 20892, USA., Zhou J; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD 20892, USA., Adeyemo A; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD 20892, USA., Rotimi CN; Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, MD 20892, USA. Electronic address: rotimic@mail.nih.gov.

Publikováno v: HGG advances [HGG Adv] 2023 Oct 12; Vol. 4 (4), pp. 100235. Date of Electronic Publication: 2023 Aug 30.