Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Goutham B. Manjunath"'
Autor:
Divakara S S M Uppu, Goutham B Manjunath, Venkateswarlu Yarlagadda, Jyothi E Kaviyil, Raju Ravikumar, Krishnamoorthy Paramanandham, Bibek R Shome, Jayanta Haldar
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0126757 (2015)
Gram-negative 'superbugs' such as New Delhi metallo-beta-lactamase-1 (blaNDM-1) producing pathogens have become world's major public health threats. Development of molecular strategies that can rehabilitate the 'old antibiotics' and halt the antibiot
Externí odkaz:
https://doaj.org/article/38adfd1742c640d09264ccf0d9c16558
Autor:
Chandradhish Ghosh, Goutham B Manjunath, Mohini M Konai, Divakara S S M Uppu, Jiaul Hoque, Krishnamoorthy Paramanandham, Bibek R Shome, Jayanta Haldar
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144094 (2015)
Development of synthetic strategies to combat Staphylococcal infections, especially those caused by methicillin resistant Staphyloccus aureus (MRSA), needs immediate attention. In this manuscript we report the ability of aryl-alkyl-lysines, simple me
Externí odkaz:
https://doaj.org/article/92683e8727d74c06af8e26c84ca16f94
Autor:
Divakara S S M Uppu, Goutham B Manjunath, Venkateswarlu Yarlagadda, Jyothi E Kaviyil, Raju Ravikumar, Krishnamoorthy Paramanandham, Bibek R Shome, Jayanta Haldar
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119422 (2015)
Gram-negative 'superbugs' such as New Delhi metallo-beta-lactamase-1 (blaNDM-1) producing pathogens have become world's major public health threats. Development of molecular strategies that can rehabilitate the 'old antibiotics' and halt the antibiot
Externí odkaz:
https://doaj.org/article/e93ac867485d472b910f2a93b310b621
Autor:
Mohini M. Konai, Jayanta Haldar, Krishnamoorthy Paramanandham, Raju Ravikumar, Goutham B. Manjunath, Bibek Ranjan Shome, Chandradhish Ghosh, Divakara S. S. M. Uppu
Publikováno v:
ACS Infectious Diseases. 2:111-122
Infections caused by drug-resistant Gram-negative pathogens continue to be significant contributors to human morbidity. The recent advent of New Delhi metallo-β-lactamase-1 (blaNDM-1) producing pathogens, against which few drugs remain active, has a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3986cdce1bcd46739aa308b7c7be39cb
https://doi.org/10.1021/acsinfecdis.5b00092
https://doi.org/10.1021/acsinfecdis.5b00092
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:5477-5480
Antibiotic-resistant superbugs such as vancomycin-resistant Enterococci (VRE) and Staphylococci have become a major global health hazard. To address this issue, we synthesized vancomycin aglycon dimers to systematically probe the impact of a linker o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c6466fc95524414b7eec09a7c49f47
https://doi.org/10.1016/j.bmcl.2015.10.083
https://doi.org/10.1016/j.bmcl.2015.10.083
Autor:
Venkateswarlu Yarlagadda, Krishnamoorthy Paramanandham, Susweta Das Mitra, Bibek Ranjan Shome, Jayanta Haldar, Paramita Sarkar, Sandip Samaddar, Goutham B. Manjunath
Publikováno v:
ACS infectious diseases. 4(7)
New Delhi metallo-β-lactamase-1 (NDM-1) is the major contributor to the emergence of carbapenem resistance in Gram-negative pathogens (GNPs) and has caused many clinically available β-lactam antibiotics to become obsolete. A clinically approved inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22bd367f909924a5c94d545b0f6ec0d3
https://pubmed.ncbi.nlm.nih.gov/29726673
https://pubmed.ncbi.nlm.nih.gov/29726673
Autor:
Goutham B. Manjunath, Krishnamoorthy Paramanandham, Jayanta Haldar, Raju Ravikumar, Paramita Sarkar, Venkateswarlu Yarlagadda, Bibek Ranjan Shome, Padma Akkapeddi
Publikováno v:
ACS Infectious Diseases. 2:132-139
The emergence of drug resistance along with a declining pipeline of clinically useful antibiotics has made it vital to develop more effective antimicrobial therapeutics, particularly against difficult-to-treat Gram-negative pathogens (GNPs). Many ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf0ecc026ccd011dca8dbb77b2ddb0b
https://doi.org/10.1021/acsinfecdis.5b00114
https://doi.org/10.1021/acsinfecdis.5b00114
Autor:
Jayanta Haldar, Spandhana Gonuguntla, Sandip Samaddar, Mohini M. Konai, Venkateswarlu Yarlagadda, Goutham B. Manjunath, Jiaul Hoque
Publikováno v:
Journal of Medicinal Chemistry. 58:5486-5500
Treating bacterial biofilms with conventional antibiotics is limited due to ineffectiveness of the drugs and higher propensity to develop bacterial resistance. Development of new classes of antibacterial therapeutics with alternative mechanisms of ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c66686c3399e2ff653b8eb3fb00a818
https://doi.org/10.1021/acs.jmedchem.5b00443
https://doi.org/10.1021/acs.jmedchem.5b00443
Autor:
Raju Ravikumar, Subhankari Prasad Chakraborty, Jayanta Haldar, Bhuvana Mani, Goutham B. Manjunath, Krishnamoorthy Paramanandham, Venkateswarlu Yarlagadda, Mohini M. Konai, Relekar G. Prakash, Shome B. Ranjan, Somenath Roy
Publikováno v:
International Journal of Antimicrobial Agents. 45:627-634
The membrane-active glycopeptide antibiotic YV11455 is a lipophilic cationic vancomycin analogue that demonstrates rapid and concentration-dependent killing of clinically relevant multidrug-resistant (MDR) Gram-positive bacteria in vitro. YV11455 was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c508527303d92e971ebd6dd61d12c21
https://doi.org/10.1016/j.ijantimicag.2015.02.013
https://doi.org/10.1016/j.ijantimicag.2015.02.013
Autor:
Jayanta Haldar, Jiaul Hoque, Padma Akkapeddi, Kaustuv Sanyal, Venkateswarlu Yarlagadda, Divakara S. S. M. Uppu, Mohini M. Konai, Vikas Yadav, Goutham B. Manjunath
Publikováno v:
ACS Applied Materials & Interfaces. 7:1804-1815
Microbial attachment and subsequent colonization onto surfaces lead to the spread of deadly community-acquired and hospital-acquired (nosocomial) infections. Noncovalent immobilization of water insoluble and organo-soluble cationic polymers onto a su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394a39d61c87291de4720be128a41180
https://doi.org/10.1021/am507482y
https://doi.org/10.1021/am507482y