Zobrazeno 1 - 10
of 546
pro vyhledávání: '"Goutam Chakraborty"'
Autor:
Sai Harisha Rajanala, Romina Ghale, Subhiksha Nandakumar, Kalyani Chadalavada, Gwo-Shu Mary Lee, Konrad H Stopsack, Yu Chen, Gouri J Nanjangud, Goutam Chakraborty, Philip W Kantoff
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301989 (2024)
Somatic Y chromosome loss in hematopoietic cells is associated with higher mortality in men. However, the status of the Y chromosome in cancer tissue is not fully known due to technical limitations, such as difficulties in labelling and sequencing DN
Externí odkaz:
https://doaj.org/article/9f025f8d20d746c0a246657541807f95
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-4 (2023)
Prostate cancer is a highly heterogeneous disease. Progression on androgen deprivation therapy (ADT) to castration-resistant (CRPC), or neuroendocrine prostate cancer (NEPC), is associated with poor patient survival. This comment highlights recent ev
Externí odkaz:
https://doaj.org/article/63f3b1e9419446a5b86c3f8cb2f24ee2
Autor:
Yuki Yoshikawa, Konrad H. Stopsack, Xin Victoria Wang, Yu‐Hui Chen, Ying Z. Mazzu, Foster Burton, Goutam Chakraborty, Sai Harisha Rajanala, Rahim Hirani, Subhiksha Nandakumar, Gwo‐Shu Mary Lee, David Frank, Elai Davicioni, Glenn Liu, Michael A. Carducci, Haruhito Azuma, Philip W. Kantoff, Christopher J. Sweeney
Publikováno v:
Molecular Oncology, Vol 16, Iss 22, Pp 3994-4010 (2022)
Loss of the histone demethylase KDM5D (lysine‐specific demethylase 5D) leads to in vitro resistance of prostate cancer cells to androgen deprivation therapy (ADT) with and without docetaxel. We aimed to define downstream drivers of the KDM5D effect
Externí odkaz:
https://doaj.org/article/f3e5c6df0fe14e4b96ddc7e70c0635e6
Autor:
Xitong Hu, Rupom Bhattacherjee, Kodjo Botchway, Jack C. Pashin, Goutam Chakraborty, Prem Bikkina
Publikováno v:
Energies, Vol 17, Iss 6, p 1349 (2024)
The storage potential of hydrocarbon reservoirs in the central Gulf of Mexico (GOM) makes future development of CO2 storage projects in those areas promising for secure, large-scale, and long-term storage purposes. Focusing on the producing and deple
Externí odkaz:
https://doaj.org/article/5cb74f06bc394167b14d96e585d54d79
Publikováno v:
IEEE Access, Vol 10, Pp 47031-47050 (2022)
Continuum manipulators are a type of robot used for delicate applications, including safe human-robot interactions. Controlling these manipulators for an accurate trajectory, especially in the case of pneumatic actuation, is extremely challenging. Th
Externí odkaz:
https://doaj.org/article/088c1491a1a7420e90ebbf70f4b1bd6c
Autor:
Trilochan Gadly, Goutam Chakraborty, Mrityunjay Tyagi, Birija S. Patro, Bijaideep Dutta, Akhilesh Potnis, Pallavi Chandwadkar, Celin Acharya, Shishu Kant Suman, Archana Mukherjee, Suman Neogy, Amey Wadawale, Srikant Sahoo, Nitish Chauhan, Sunil K. Ghosh
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Cellular temperature and pH govern many cellular physiologies, especially of cancer cells. Besides, attaining higher cellular temperature plays key role in therapeutic efficacy of hyperthermia treatment of cancer. This requires bio-compatibl
Externí odkaz:
https://doaj.org/article/afb641219027487cb742a5ffca4889f5
Autor:
Hyunho Han, Yan Wang, Josue Curto, Sreeharsha Gurrapu, Sara Laudato, Alekya Rumandla, Goutam Chakraborty, Xiaobo Wang, Hong Chen, Yan Jiang, Dhiraj Kumar, Emily G. Caggiano, Monica Capogiri, Boyu Zhang, Yan Ji, Sankar N. Maity, Min Hu, Shanshan Bai, Ana M. Aparicio, Eleni Efstathiou, Christopher J. Logothetis, Nicholas Navin, Nora M. Navone, Yu Chen, Filippo G. Giancotti
Publikováno v:
Cell Reports, Vol 39, Iss 1, Pp 110595- (2022)
Summary: Bioinformatic analysis of 94 patient-derived xenografts (PDXs), cell lines, and organoids (PCOs) identifies three intrinsic transcriptional subtypes of metastatic castration-resistant prostate cancer: androgen receptor (AR) pathway + prostat
Externí odkaz:
https://doaj.org/article/577c4a7ae5774bfabb0ebff830f751f6
Autor:
Ying Z. Mazzu, Joshua Armenia, Subhiksha Nandakumar, Goutam Chakraborty, Yuki Yoshikawa, Lina E. Jehane, Gwo‐Shu Mary Lee, Mohammad Atiq, Nabeela Khan, Nikolaus Schultz, Philip W. Kantoff
Publikováno v:
Molecular Oncology, Vol 14, Iss 8, Pp 1881-1897 (2020)
Although there are molecularly distinct subtypes of prostate cancer, no molecular classification system is used clinically. The ribonucleotide reductase small subunit M2 (RRM2) gene plays an oncogenic role in many cancers. Our previous study elucidat
Externí odkaz:
https://doaj.org/article/a67bfa99d1ad45d6a66edcca61774047
Autor:
Sanjit Debnath, Goutam Chakraborty, Suvendhu S Dutta, Shaon Ray Chaudhury, Panna Das, Ajay Krishna Saha
Publikováno v:
Biotecnología Vegetal, Vol 20, Iss 1, Pp 01-16 (2020)
Rice (Oryza sativa L.) is one of the main staples around the world, especially in Asia, the most consuming region. Rice cultivation currently faces many environmental problems caused by the contribution of chemical fertilizers and pesticides. This re
Externí odkaz:
https://doaj.org/article/62b4a1a1e8414455bbdb50efe1f3f942
Autor:
Ying Z. Mazzu, Yuki Yoshikawa, Subhiksha Nandakumar, Goutam Chakraborty, Joshua Armenia, Lina E. Jehane, Gwo‐Shu Mary Lee, Philip W. Kantoff
Publikováno v:
Molecular Oncology, Vol 13, Iss 9, Pp 1944-1958 (2019)
Epigenetic silencing of miRNA is a primary mechanism of aberrant miRNA expression in cancer, and hypermethylation of miRNA promoters has been reported to contribute to prostate cancer initiation and progression. Recent data have shown that the miR‐
Externí odkaz:
https://doaj.org/article/68afe51bc4754a7eaf9d362267c6ab6a