Výsledky vyhledávání - "Gout/metabolism"

Inflammation in gout: mechanisms and therapeutic targets

Autor: So, A.K., Martinon, F.

Publikováno v: Nature Reviews. Rheumatology, vol. 13, no. 11, pp. 639-647

The acute symptoms of gout are triggered by the inflammatory response to monosodium urate crystals, mediated principally by macrophages and neutrophils. Innate immune pathways are of key importance in the pathogenesis of gout, in particular the activ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1900::5d25e74aab8c1d99877467dac1d0af6d
https://serval.unil.ch/resource/serval:BIB_F8C4ACBA5649.P001/REF.pdf

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Autor: Holzinger Dirk, Nippe Nadine, Vogl Thomas, Marketon Kristina, Mysore Vijayashree, Weinhage Toni, Dalbeth Nicola, Pool Bregina, Merriman Tony, Baeten Dominique, Ives Annette, Busso Nathalie, Foell Dirk, Bas Sylvette, Gabay Cem, Roth Johannes

Publikováno v: Arthritis and rheumatology, Vol. 66, No 5 (2014) pp. 1327-39
Arthritis & rheumatology (Hoboken, N.J.), 66(5), 1327-1339. John Wiley and Sons Ltd
Arthritis & rheumatology (Hoboken N.J.)

Monosodium urate monohydrate (MSU) crystal-induced interleukin-1β (IL-1β) secretion is a critical factor in the pathogenesis of gout. However, without costimulation by a proIL-1β-inducing factor, MSU crystals alone are insufficient to induce IL-1�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e85bc2ccbc892736d70804877ef4b9cb
https://archive-ouverte.unige.ch/unige:45956

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High-density lipoproteins downregulate CCL2 production in human fibroblast-like synoviocytes stimulated by urate crystals

Autor: Leonardo Punzi, Anna Scanu, Carlo Agostini, Danielle Burger, Federica Frezzato, Assunta Pozzuoli, Lyssia Gruaz, Paolo Sfriso, Francesca Oliviero

Publikováno v: Arthritis Research & Therapy
Arthritis Research and Therapy, Vol. 12, No 1 (2010) P. R23

INTRODUCTION: To investigate whether monosodium urate (MSU) crystals induce the production of CCL2 (monocyte chemoattractant protein-1; MCP-1) in human fibroblast-like synoviocytes (FLS) and whether this mechanism would be affected by high-density li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bdbc2540601df1edac7bab4c8b7775b
https://doi.org/10.1186/ar2930

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Lactate levels in Brucella arthritis

Autor: Mavridis, A. K., Drosos, A. A., Tsolas, O., Moutsopoulos, H. M.

In this study the synovial fluid cell types and the synovial fluid lactate levels of patients with Brucella, septic rheumatoid, gouty and osteoarthritic mono-arthritis are presented. It is shown that lactate levels coupled with the clinical picture a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10561::306e01bb272867041c551d15b657194f
http://olympias.lib.uoi.gr/jspui/handle/123456789/20513

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